Traditional Chinese medicine composition for treating rheumatism bone disease, and preparation method and application of Chinese patent medicines
A technology for rheumatic bone disease and Chinese patent medicine, which is applied in the field of Chinese patent medicine, can solve the problems of large dosage, high potential safety risks, toxic and side effects, etc. Ability, TNF-α-promoting effect
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Embodiment 1
[0067] A traditional Chinese medicine prescription for treating rheumatic bone disease, the formula mass percentage of each active part is as follows:
[0068] Glycyrrhizin 54%;
[0069] Licorice Flavonoids 18%;
[0070] Ephedra alkaloids 12 %;
[0071] Achyranthes saponins 9%;
[0072] Nuxychon alkaloids 7%.
[0073] The method for preparing the Chinese patent medicine for the treatment of rheumatic bone disease according to the Chinese medicine prescription of the present invention, comprises the following steps:
[0074] (1) Preparation of Glycyrrhizin
[0075] ① Extract licorice powder with 0.5% ammoniacal 70% ethanol (the percentages of the reagents mentioned below are all mass percentages) and ultrasonically extract twice, each time for 1 hour;
[0076] ② Extract by filtration and centrifugation, rotary steam to about 300mL, add deionized water, let stand overnight, and centrifuge;
[0077] ③ Pass through the HZ-816 macroporous resin column (use 1200mL deionized wa...
Embodiment 2
[0103] According to the Chinese medicine prescription of the present invention, the method for preparing a Chinese patent medicine for the treatment of rheumatic bone disease comprises the following steps:
[0104] Preparation method and step are substantially the same as Example 1, and the difference from Example 1 is:
[0105] Glycyrrhizin, licorice flavonoids, ephedra alkaloids, achyranthes saponins and strychnium alkaloids prepared in steps (1)-(5) were prepared according to the traditional Chinese medicine prescription for treating rheumatic bone disease, and the quality of each active part The percentage is:
[0106] Glycyrrhizin 40%;
[0107] Licorice Flavonoids 10%;
[0108] Ephedra alkaloids 20%;
[0109] Sichuan achyranthes saponins 20%;
[0110] Nuxychon alkaloids 10%.
Embodiment 3
[0112] According to the Chinese medicine prescription of the present invention, the method for preparing a Chinese patent medicine for the treatment of rheumatic bone disease comprises the following steps:
[0113] Preparation method and step are substantially the same as Example 1, and the difference from Example 1 is:
[0114] Glycyrrhizin, licorice flavonoids, ephedra alkaloids, achyranthes saponins and strychnium alkaloids prepared in steps (1)-(5) were prepared according to the traditional Chinese medicine prescription for treating rheumatic bone disease, and the quality of each active part The percentage is:
[0115] Glycyrrhizin 60%;
[0116] Licorice Flavonoids 20%;
[0117] Ephedra alkaloids 10%;
[0118] Achyranthes saponins 5%;
[0119] Nuxychon alkaloids 5%.
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