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Antibacterial healing-functional dressing and preparation method thereof

A functional and raw material technology, applied in medical science, bandages, absorbent pads, etc., can solve the problems of unsatisfactory requirements, poor mechanical properties of the gel, unsuitable for use, etc., achieve excellent antibacterial properties, prevent agglomeration or sedimentation, and enhance mechanical properties intensity effect

Active Publication Date: 2014-05-21
WUHAN LANGQI BIOLOGICAL SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It forms a gel around the wound, which can quickly absorb a large amount of wound exudate, but it should not be used on dry and hard wounds
[0005] A Chinese invention patent application with application number 201310520955.5 discloses a functional dressing and its preparation method, which consists of 2-6 parts of bioactive glass, 12-20 parts of alginate, 4-12 parts of chitosan, and 100-100 parts of water. 200 parts were formulated, but the mechanical properties of the formed gel were poor and could not meet the requirements

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Every 100g product contains 0.1g of chitosan quaternary ammonium salt, 1g of bean and cereal extract, wherein the bean and cereal extract is prepared by soybean extract and corn extract according to the ratio of parts by weight of 1:1, glycerin 10g, and the balance is water.

[0026] The preparation method is as follows: uniformly disperse 0.1 g of chitosan quaternary ammonium salt in 10 g of glycerin, and fully dissolve to obtain a phase A solution; fully dissolve 1 g of bean and cereal extracts in purified water to obtain a B phase solution; Mix well and stir for 30 minutes.

Embodiment 2

[0028] Every 100g product contains 1g of chitosan quaternary ammonium salt, 2g of bean and cereal extract, wherein the bean and cereal extract is soybean extract, 20g of glycerin, and the balance is water.

[0029] The preparation method is as follows: uniformly disperse 1g of chitosan quaternary ammonium salt in 20g of glycerin, and fully dissolve to obtain a phase A solution; fully dissolve 2g of bean and cereal extracts in purified water to obtain a B phase solution; Mix well and stir for 30 minutes.

Embodiment 3

[0031] Every 100g product contains 1.5g of chitosan quaternary ammonium salt, 2.5g of bean and cereal extract, wherein the bean and cereal extract is prepared from soybean extract and sorghum extract according to the weight and number ratio of 2:3, glycerin 20g, and the balance is water.

[0032] The preparation method is as follows: uniformly disperse 1.5g of chitosan quaternary ammonium salt in 20g of glycerin, and fully dissolve to obtain a phase A solution; fully dissolve 2.5g of bean and grain extracts in purified water to obtain a B phase solution; The phase solution was uniformly mixed and stirred for 30 minutes.

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Abstract

The invention discloses antibacterial healing-functional dressing and a preparation method thereof. The antibacterial healing-functional dressing is characterized by being prepared by mixing the following raw material components by weight: 0.1-3g of chitosan quaternary ammonium salt, 0.1-5g of a bean and grain type extractive, 1-30g of glycerinum and the balance of purified water in every 100g of a finished product. The chitosan quaternary ammonium salt can be adopted to form an isolating membrane on the surface of a wound to realize antibacterial action and bacteriostatic action; the bean and grain type extractive is a pure natural plant extractive which contains an interfacial agent and is a powerful bactericide. The antibacterial healing-functional dressing disclosed by the invention has the advantages of being safe, efficient and free of stimulation as well as toxic and side effects, and is convenient and simple to use, so the antibacterial healing-functional dressing is a novel wound surface disinfection and sterilization healing product worth of popularization.

Description

technical field [0001] The invention relates to a biological dressing, in particular to a kind of wound surface used for surgical incision wounds and mechanical traumas. Background technique [0002] In the process of wound healing, in order to accelerate wound healing and reduce wound infection, it is necessary to cover the wound with an appropriate dressing, so the medical dressing should have good permeability, absorb the exudate of the wound, be easy to remove, and be non-toxic. It has the characteristics of non-toxic, non-irritating, good mechanical properties, and less scars after healing. [0003] The Chinese invention patent application with the application number 200510134590.8 discloses a medical dressing, which is characterized by an inner layer containing chitosan fibers and an outer layer containing polytetrafluoroethylene film, but because the surface of the inner layer chitosan fibers is rough, and The elasticity is poor, and it is easy to cause secondary dam...

Claims

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Application Information

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IPC IPC(8): A61L15/40A61L15/28A61L15/44
Inventor 李燃
Owner WUHAN LANGQI BIOLOGICAL SCI & TECH
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