Preparation method of ageratum conyzoides volatile oil microcapsule and antibacterial application thereof

A technology for volatile oil and Agaricus vulgaris, which is applied in the field of preparation of volatile oil microcapsules of Agaricus vulgaris, can solve problems such as unpublished literature reports and the like, and achieves the effects of simple and feasible technical route, good reactivity, and avoiding oxidation and volatilization.

Inactive Publication Date: 2014-10-01
NANJING ZELANG MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0006] Through literature search, do not see the public

Method used

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  • Preparation method of ageratum conyzoides volatile oil microcapsule and antibacterial application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Add 66g of maltodextrin and gelatin with a mass ratio of 2:1 to 132mL of water, stir and dissolve to obtain a wall material solution; add 4g of emulsifier Tween-20 and 30g of Ageratum volatile oil to the wall material solution , stirred at 10000r / min at high speed for 10min, then passed into a high-pressure homogenizer, and homogenized three times at a temperature of 70°C and a pressure of 20MPa to form a mixture with uniform particle size to obtain an emulsion; °C, air outlet temperature of 80 °C, and atomization pressure of 0.5 MPa to obtain ageratum volatile oil microcapsules with an average particle size of 15 μm.

Embodiment 2

[0035] Add 74g of maltodextrin and gelatin with a mass ratio of 2:1 to 74mL of water, stir and dissolve to obtain a wall material solution; add 2g of emulsifier Tween-20 and 24g of Ageratum volatile oil to the wall material solution , stirred at a high speed of 15000r / min for 10min, then passed into a high-pressure homogenizer, and homogenized three times at a temperature of 80°C and a pressure of 40MPa to form a mixture with uniform particle size to obtain an emulsion; °C, air outlet temperature of 100 °C, and atomization pressure of 0.2 MPa to obtain ageratum volatile oil microcapsules with an average particle size of 50 μm.

Embodiment 3

[0037] Add 70g of maltodextrin and gelatin with a mass ratio of 2:1 to 210mL of water, stir and dissolve to obtain a wall material solution; add 3g of emulsifier Tween-20 and 27g of ageratum volatile oil to the wall material solution , stirred at a high speed of 12000r / min for 10min, then passed into a high-pressure homogenizer, and homogenized three times at a temperature of 70°C and a pressure of 20MPa to form a mixture with uniform particle size to obtain an emulsion; °C, air outlet temperature of 90 °C, and atomization pressure of 0.3 MPa to obtain ageratum volatile oil microcapsules with an average particle size of 30 μm.

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Abstract

The invention discloses a preparation method of an ageratum conyzoides volatile oil microcapsule and an antibacterial application thereof. The preparation method comprises the following steps: dissolving maltodextrin and gelatin by water, and evenly agitating to obtain a wall solution; adding an emulsifier and ageratum conyzoides volatile oil to the wall material, and homogenizing to obtain an emulsion; and carrying out spray drying on the emulsion, so as to obtain the ageratum conyzoides volatile oil microcapsule. The obtained ageratum conyzoides volatile oil microcapsule forms a powder form, is good in water solubility and stability, high in embedding rate and slow to release, has significant antibacterial activity, and can be applied to the fields such as household necessities, medicines and the like.

Description

technical field [0001] The invention relates to a preparation method of ageratum volatile oil microcapsules and its antibacterial application. Background technique [0002] Ageratum thistle, also known as red thistle, is an annual herb of the genus Ageratum in the family Asteraceae. It has anti-inflammatory and bactericidal, heat-clearing and detoxifying, hemostatic, and analgesic effects. It is a traditional folk medicinal plant in various countries in the world. It is used by folks in southern China to treat colds and fevers, sore throat, ulcers, and traumatic bleeding. [0003] Volatile oil is a class of active ingredients in traditional Chinese medicine, widely distributed in the plant kingdom, and has a variety of pharmacological activities and a wide range of uses. At present, most of the researches on the volatile oil of ageratum are the antioxidant activity of the volatile oil, but there is no research on its antibacterial activity. Therefore, the research on the a...

Claims

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Application Information

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IPC IPC(8): A61K36/28A61K9/50A61P31/04
Inventor 刘东锋杨成东
Owner NANJING ZELANG MEDICAL TECH
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