A fully automatic sampling mechanism for flow cytometer

Abstract

The invention discloses a fully automatic sample feeding mechanism for a flow cytometer, which comprises a rotating disc with a number of test tube mounting holes distributed radially, and a fixed plate on one side of the rotating disc. X to the drive mechanism, and with X The sampling needle connected to the drive mechanism and Z to the drive mechanism, X The drive mechanism includes a X to the slide rail, set at X To the sampling needle drive plate on the slide rail, and for driving the sampling needle drive plate along the X The steering gear link drive mechanism that makes horizontal reciprocating motion to the slide rail, and at the same time Z Connect the base of the rotating disk to the driving mechanism through the connecting plate and drive the rotating disk to make Z Reciprocate vertically, and the connecting plate is connected with the base through the rotating telescopic shaft arranged radially along the rotating disk, and the connecting plate is connected with the base by means of X Drive the sampling needle edge on the sampling needle drive plate to the slide rail and the steering gear linkage drive mechanism X The horizontal reciprocating movement toward the slide rail not only has a simple structure, but also takes up less space, and the horizontal movement of the sampling needle is also more stable.

Description

technical field [0001] The invention relates to a sample feeding mechanism, in particular to a fully automatic sample feeding mechanism for a flow cytometer. Background technique [0002] Flow cytometry is a device for automatic analysis and sorting of cells. It can quickly measure, store and display a series of important biophysical and biochemical characteristic parameters of dispersed cells suspended in liquid, and can sort out specified cell subpopulations according to the preselected parameter range. [0003] The flow cytometer in the prior art has an important link before measurement, that is, the sampling link. For the sampling mechanism of the flow cytometer in the prior art, a driving motor is used to drive the sampling needle for sampling, which not only increases the overall flow cytometer Occupies space, and is directly driven by a drive motor, which may easily cause unstable movement of the sampling needle and low sampling accuracy; at the same time, because th...

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Problems solved by technology

[0003] In the prior art, the flow cytometer has an important link before measurement, that is, the sampling link. For the sampling mechanism of the flow cytometer in the prior art, a The driving motor drives the sampling needle to take samples, which not only increases the overall space occupied by the flow cytometer, but also directly drives the driving motor, which may easily cause unstable movement of the sampling needle and low sampling accuracy; at the same time, because the flow cytometer samples from the test tube, However, the caliber of the test tubes used in the prior art is generally narrow, and it is impossible to add a stirring mechanism when extracting the liquid to be tested, resulting in inaccurate detected data. In view of the above technical problems, the prior art also proposes an integrated sampling and stirring mechanism. The sampling mechanism includes a vibrating plate that swings left and right. The vibrating plate is connected to the sampling needle, and the vibrating plate drives the sampling needle to swing left and right or back and forth. The swing direction is single, the stirring effect is not good, and the swing range is not easy to control. In the process of swinging, it is easy to touch the inner wall of the test tube, and even damage the test tube and sampling needle

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