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A kind of pharmaceutical composition for treating dry eye syndrome and application thereof

A dry eye syndrome and composition technology, which is applied in the direction of drug combination, drug delivery, medical preparations of non-active ingredients, etc., can solve the problems of no radical cure, unsatisfactory curative effect, easy recurrence, etc., and achieve remarkable curative effect , Prolong tear film break-up time, increase the effect of tear secretion

Inactive Publication Date: 2016-03-09
NANTONG QIWU AGRI PROD CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, artificial tears can only relieve local dryness and astringency symptoms, and cannot achieve a radical effect. It is very easy to relapse after stopping the drug, so the curative effect is not ideal.

Method used

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  • A kind of pharmaceutical composition for treating dry eye syndrome and application thereof
  • A kind of pharmaceutical composition for treating dry eye syndrome and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Weigh 250g of ginkgo leaves, 250g of ghost needle grass, 380g of emblica, 250g of mulberry leaves, and 100g of golden cherry seeds and combine them. Add water to be 8 times the weight of the medicinal materials, decoct for 1.5 hours, combine the decoctions, concentrate under reduced pressure at 0.08MPa and 70°C until the relative density is 1.15 at 70°C, add 95% (v / v) ethanol to make the alcohol content reach 75% (v / v), stirred, stood overnight, filtered, and the filtrate was concentrated under reduced pressure at 0.08MPa and 65°C to contain 3.5g / mL of the original drug, and 0.25% preservative potassium sorbate was added. Bottled.

Embodiment 2

[0018] Weigh 285g of ginkgo leaves, 210g of ghost needle grass, 350g of emblica, 220g of mulberry leaves, and 130g of golden cherry seeds and combine them, add water to decoct twice, add water for the first time to 10 times the weight of the medicinal materials, decoct for 2 hours, and decoct for the second time Add water to be 8 times the weight of the medicinal materials, decoct for 1.5 hours, combine the decoctions, concentrate under reduced pressure at 0.08MPa and 70°C until the relative density is 1.15 at 70°C, add 95% (v / v) ethanol to make the alcohol content reach 85% (v / v), stirred, stood overnight, filtered, and the filtrate was concentrated under reduced pressure at 0.08MPa and 65°C to contain 3.5g / mL of the crude drug, and 0.25% preservative potassium sorbate was added. Bottled.

Embodiment 3

[0020] Weigh 220g of ginkgo leaves, 250g of ghost needle grass, 460g of emblica, 300g of mulberry leaves, and 80g of golden cherry seeds and combine them, add water to decoct twice, add water for the first time to 10 times the weight of the medicinal materials, decoct for 2 hours, and decoct for the second time Add water to be 8 times the weight of the medicinal materials, decoct for 1.5 hours, combine the decoctions, concentrate under reduced pressure at 0.08MPa and 70°C until the relative density is 1.20 at 70°C, add 95% (v / v) ethanol to make the alcohol content reach 80% (v / v), stirred, stood overnight, filtered, and the filtrate was concentrated under reduced pressure at 0.08MPa and 65°C to contain 3.5g / mL of the crude drug, and 0.25% preservative potassium sorbate was added. Bottled.

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PUM

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Abstract

The invention discloses a medicinal composition for treating a dry eye disease and application thereof. The medicinal composition for treating the dry eye disease is prepared from the following traditional Chinese medicine raw materials in parts by weight through water extraction and alcohol precipitation: 21-30 parts of ginkgo leaf, 21-30 parts of sticktight, 32-46 parts of emblic leafflower fruit, 21-30 parts of mulberry leaf and 8-13 parts of cherokee rose fruit. The medicinal composition for treating the dry eye disease has the effects of nourishing yin, moistening dryness, nourishing blood and improving eyesight, so that aqueous humor is produced, eyes are moistened and nourished, and eyeballs are lubricated.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a pharmaceutical composition for treating dry eye and its application. Background technique [0002] Dry eye, also known as xerophthalmia, refers to the lack or abnormal distribution of tears in front of the cornea, which leads to a decrease in tears and dryness of the eyeball surface. This can lead to abrasion, inflammation and even ulceration of the corneal surface, ultimately affecting vision. [0003] Western medicine believes that xerophthalmia is mainly related to factors such as excessive eye use, immune inflammatory response, abuse of antibiotics, and age. The main method of Western medicine to treat xerophthalmia is to locally use artificial tears that imitate the physical and chemical properties of human tears to stimulate tear secretion, increase ocular surface humidity, and improve corneal lubrication, thereby alleviating discomfort s...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/738A61P27/02
CPCA61K9/0048A61K9/0095A61K36/16A61K36/28A61K36/47A61K36/605A61K36/738A61K47/26A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 姜良柱邱世彦
Owner NANTONG QIWU AGRI PROD CO LTD
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