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Antibacterial hydrocolloid dressing and preparation method thereof

A hydrocolloid and hydrocolloid layer technology, applied in medical science, bandages, absorbent pads, etc., can solve problems such as the inability to meet the diverse needs of complex wounds, and achieve a biosafety risk, good safety, and strong antibacterial properties. Effect

Active Publication Date: 2014-12-24
HENAN HUIBO MEDICAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the existing hydrocolloid dressings generally only have the ability to keep the wound moist, and cannot meet the diverse needs of complex wounds

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] The antibacterial hydrocolloid dressing of the present invention comprises a backing layer, a hydrocolloid layer and a peeling layer, the hydrocolloid layer is arranged on the backing layer, and the peeling layer is arranged on the hydrocolloid layer; the backing layer is a waterproof polyurethane material, and the The peeling layer is a release paper or a release film, and the hydrocolloid layer is made of the following raw materials in parts by weight: 5 parts of polyurethane rubber, 5 parts of disproportionated rosin ester, 1 part of polyisobutylene with a molecular weight of 300, thio 0.5 part of dioctadecyl dipropionate, 30 parts of sodium carboxymethyl cellulose, 5 parts of polyvinyl alcohol, 1 part of acylated chitosan with a molecular weight of 5000-8000, and 0.05 part of polyhexamethyleneguanidine.

[0027] The method for preparing described antibacterial hydrocolloid dressing can be carried out in the following steps:

[0028] ① Put 5 parts by weight of polyur...

Embodiment 2

[0031] The antibacterial hydrocolloid dressing of the present invention comprises a backing layer, a hydrocolloid layer and a peeling layer, the hydrocolloid layer is arranged on the backing layer, and the peeling layer is arranged on the hydrocolloid layer; the backing layer is a waterproof polyurethane material, and the The peeling layer is a release paper, and the hydrocolloid layer is made of the following raw materials in parts by weight: 7 parts of butyl rubber, 8 parts of disproportionated rosin ester, 2 parts of polyisobutylene with a molecular weight of 400, thiodipropionic acid 0.8 parts of dioctadecyl ester, 32 parts of sodium carboxymethylcellulose, 5.5 parts of polyvinyl alcohol, 1.5 parts of acylated chitosan with a molecular weight of 8000-10000, and 0.1 part of polyhexamethyleneguanidine.

[0032] The method for preparing described antibacterial hydrocolloid dressing can be carried out in the following steps:

[0033] ① Add 7 parts by weight of butyl rubber, 8 ...

Embodiment 3

[0036] The antibacterial hydrocolloid dressing of the present invention comprises a backing layer, a hydrocolloid layer and a peeling layer, the hydrocolloid layer is arranged on the backing layer, and the peeling layer is arranged on the hydrocolloid layer; the backing layer is a waterproof polyurethane material, and the The peeling layer is a release paper, and the hydrocolloid layer is made of the following raw materials in parts by weight: 9 parts of styrene block copolymer thermoplastic elastomer, 10 parts of disproportionated rosin ester, 4 parts of polyisobutylene with a molecular weight of 500 , 1 part of dioctadecyl thiodipropionate, 35 parts of sodium carboxymethylcellulose, 7 parts of polyvinyl alcohol, 2 parts of acylated chitosan with a molecular weight of 10000~50000, polyhexamethyleneguanidine hydrochloride 0.2 parts of salt.

[0037] The method for preparing described antibacterial hydrocolloid dressing can be carried out in the following steps:

[0038]① Add ...

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PUM

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Abstract

The invention provides antibacterial hydrocolloid dressing and a preparation method thereof, and belongs to the technical field of medical dressing. The preparation method of the antibacterial hydrocolloid dressing is as follows: firstly, elastomers, tackifying resin, a plasticizer and an antioxidant are added into an internal mixer and mixed to prepare a hot-melt pressure-sensitive adhesive; hydrocolloid particles, polyvinyl alcohol, chitosan derivative and an antibacterial agent are added into the hot-melt pressure-sensitive adhesive and mixed; and the mixture is placed in a press vulcanizer for treatment, a waterproof polyurethane backing is coated with the treated mixture, release paper is covered, and a finished product is prepared after irradiation sterilization. The anti-bacterial hydrocolloid dressing prepared with the method has good antibacterial performance and has no safety risk; and the polyvinyl alcohol ingredient added in the preparation process is crosslinked during irradiation to form physical gel, the integrity of the dressing is effectively maintained, and the corrosion resistance of the dressing is improved.

Description

technical field [0001] The invention belongs to the technical field of medical dressings, and in particular relates to an antibacterial hydrocolloid dressing and a preparation method thereof. Background technique [0002] Hydrocolloid medical dressing is a medical dressing made by blending water-absorbing polymer particles with hot-melt pressure-sensitive adhesive. This material combines the adhesive properties of rubber materials with the water absorption properties of absorbent polymer materials. The rubber base material provides stickiness, which enables the dressing to stick to the wound surface, while the hydrocolloid particles dispersed in it swell after absorbing water, providing a moist and airtight environment for the wound, and promoting wound healing. A humid environment can promote wound healing and bring great convenience to wound care. [0003] However, traditional hydrocolloid dressings have no antibacterial properties, and are often unsatisfactory when deal...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/30A61L15/24A61L15/46A61L15/44
Inventor 朱天钢刘尧李延浩周新钦
Owner HENAN HUIBO MEDICAL CO LTD
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