Polypeptide inhibitor for inhibiting aggregation and toxicity of beta amyloid protein and application of polypeptide inhibitor
An amyloid and toxicity technology, applied in the field of biomedicine, can solve the problems of no reports, and achieve the effect of reducing the content and inhibiting the fibrillar assembly behavior
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[0034] The technical solutions of the present invention will be further described below in conjunction with the accompanying drawings and through specific implementation methods.
[0035] Unless otherwise specified, the reagents used in the following examples are of analytical grade and can be purchased commercially from formal channels.
[0036] Unless otherwise specified, the neuroma cell line SH-SY5Y used in the following examples was purchased from the Basic Medical Cell Center, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences.
[0037] Unless otherwise specified, the β-amyloid protein (Aβ) used in the following examples was purchased from Shanghai Gil Biochemical Technology Co., Ltd., and its purity was >95%.
[0038] Unless otherwise specified, the peptides used in the following examples were prepared by Shanghai Keyept Biotechnology Co., Ltd. using solid-phase peptide synthesis with a purity of >98%.
[0039] Unless otherwise specified, the ultr...
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