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Chinese medicinal preparation for treating stomachache and diarrhea

A traditional Chinese medicine preparation and diarrhea technology, which is applied in the direction of non-central analgesics, medical preparations containing active ingredients, antipyretics, etc., can solve the problems of large individual differences in curative effect, inconvenient carrying, etc., and achieve quick results and improved digestive function. Strong, conditioning therapeutic effect

Inactive Publication Date: 2015-02-11
崔银方
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0015] The inventor combined his years of experience in clinical Chinese medicine, on the basis of summarizing traditional prescriptions, fully studied the characteristics of modern people's disease and modern pharmaceutical technology, and invented a Chinese medicine formula that has a significant effect on acute and chronic abdominal pain and diarrhea. And a preparation process was tailored for this formula, which overcomes the shortcomings of traditional Chinese medicine, such as taking, inconvenient to carry, and large individual differences in curative effect.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0059] In order to provide medicines for acute and chronic toxicity tests and clinical trials, and to verify the preparation process of the present invention, the traditional Chinese medicine oral liquid is produced according to the practice of the traditional Chinese medicine formula of the present invention, and the gained oral liquid is respectively numbered A, B, C, D, E, F, wherein, A, B and C are 3 preferred ratios respectively, D is the maximum range ratio of the formula, E is the smallest range ratio of the formula, and F is any ratio within the range of the formula. The quantities of Chinese herbal medicines in each proportion are shown in Table 1.

[0060] Table 1 Quantity table of Chinese herbal medicines in each proportion (unit: kg)

[0061]

[0062] Step 1. Accurately weigh Gallus gallis, Divine Comedy, Pomegranate Peel, Magnolia Bark, Evodia, Tangerine Peel, Papaya, Agrimony, Campanulaceae, Perilla Leaf, Atractylodes Rhizome, Pinellia, Fangfeng, Atractylodes ...

Embodiment 2

[0068] Embodiment 2, the animal toxicity test of Chinese medicine oral liquid of the present invention

[0069] (1) Acute toxicity test

[0070] 1. Experimental medicines: the Chinese medicine oral liquid prepared in Example 1 of the present invention is numbered A-F. Animals used in the test: ordinary NIH mice, weighing 21g±6g, half male and half female, and all female mice are sterile;

[0071] 2. The application of mice to carry out acute toxicity experiments showed that: mice were given the traditional Chinese medicine oral liquid of Example 1, at a dose of 784.9g crude drug / kg, after administration, the mice showed a slight decrease in activity, and returned to normal in about 1 hour. After continuous observation for 7 days, none of the mice died, and the general condition, diet, water intake, urination and weight gain were all normal. Experimental result shows: the maximum administration amount of the traditional Chinese medicine oral liquid of mouse gavage embodiment ...

Embodiment 3

[0080] Embodiment 3, the clinical effect test of Chinese medicine oral liquid of the present invention

[0081] 1. Subject information

[0082] The subjects came from patients with abdominal pain and diarrhea admitted to the Third People's Hospital of a certain city from February 2012 to January 2014, and 172 patients suitable for clinical trials were screened out. Among them, there were 72 males, aged 18-72 years, 32 cases of acute abdominal pain and diarrhea, 40 cases of chronic abdominal pain and diarrhea; 100 females, aged 19-69 years, 44 cases of acute abdominal pain and diarrhea, and 56 cases of chronic abdominal pain and diarrhea. All patients were equally divided into 4 groups according to their condition, sex, age, etc., with 43 cases in each group, which were the control group, group A, group B, and group C.

[0083] 2. Experimental drug

[0084] (1) Belladonna sulfbenzidine tablets, specifications: 10 tablets, sulfamethoxazole 0.4 g, trimethoprim 80 mg, belladonna...

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Abstract

The invention discloses a Chinese medicinal preparation for treating stomachache and diarrhea and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine. The Chinese medicinal preparation is prepared from the raw materials of chicken's gizzard membrane, medicated leaven, pomegranate peel, officinal magnolia bark, medicinal evodia fruit, dried orange peel, pawpaw, hairyvein agrimonia herb and bud, platycodon root, perilla leaf, Chinese atractylodes, pinellia tuber, divaricate saposhnikovia root, bighead atractylodes rhizome, Chinese mosla herb, hawthorn, combined spicebush root, poria cocos, notopterygium root, wrinkled gianthyssop herb, costus root, dahurian angelica root, fructus amomi, nutgrass galingale rhizome and liquoric root. The Chinese medicinal materials can be prepared into the Chinese medicinal preparation which has a stable curative effect and is convenient to take through the preparation method thereof and a modern preparation process; the Chinese medicinal preparation has very remarkable treatment effects on acute and chronic stomachache and diarrhea; moreover, a preparation process is easy, convenient and feasible in operation, and is easy to popularize and apply.

Description

technical field [0001] The invention discloses a traditional Chinese medicine preparation for treating abdominal pain and diarrhea and a preparation process thereof, belonging to the technical field of traditional Chinese medicine. technical background [0002] Diarrhea is a common symptom, commonly known as "diarrhea", which refers to the frequency of defecation significantly exceeding the usual habit, thin fecal matter, increased water content, daily defecation volume exceeding 200g, or containing undigested food or pus, blood, and mucus. Diarrhea is often accompanied by symptoms such as urgency to defecate, anal discomfort, and incontinence. Diarrhea is divided into acute and chronic categories. The onset of acute diarrhea is sharp, and the course of the disease is within 2-3 weeks. Chronic diarrhea refers to recurrent diarrhea with a course of more than two months or an intermittent period within 2-4 weeks. [0003] Diarrhea is commonly known as "diarrhea". Traditiona...

Claims

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Application Information

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IPC IPC(8): A61K36/9064A61P29/00A61P1/12A61K35/57
CPCA61K35/57A61K9/0053A61K36/00A61K36/076A61K36/185A61K36/232A61K36/237A61K36/238A61K36/284A61K36/285A61K36/34A61K36/484A61K36/53A61K36/532A61K36/535A61K36/54A61K36/575A61K36/73A61K36/732A61K36/734A61K36/752A61K36/754A61K36/8888A61K36/8905A61K36/9064A61K2236/15A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 高建飞慕海连
Owner 崔银方
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