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A traditional Chinese medicine composition for treating chronic hypoxic pulmonary diseases and its preparation method

A composition and pulmonary technology, applied in the field of biomedicine, can solve problems such as inability to cure chronic hypoxic pulmonary diseases, and achieve the effects of enhancing cellular immunity and humoral immunity, shortening coagulation time, and reducing thrombosis.

Active Publication Date: 2018-08-28
昆明市中医医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In order to solve the problem that it is difficult to cure chronic hypoxic pulmonary diseases in the prior art, the present invention provides a traditional Chinese medicine composition for treating chronic hypoxic pulmonary diseases and its preparation method, so as to give full play to the advantages of overall regulation of traditional Chinese medicine

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] (1) Prepare materials according to the following components by mass: 3 parts of Panax notoginseng, 25 parts of Rhodiola rosea, and 15 parts of Dilong;

[0019] (2) Grinding 1 / 2 of the notoginseng prepared in step (1) to a fine powder with a particle size of 80 mesh;

[0020] (3) Mix the remaining part of Panax notoginseng prepared in step (1) with Rhodiola rosea for coarse crushing until the particle size is 10 mesh, and then use 8 mass times and 6 mass times of ethanol with a concentration of 70v / v% respectively for Reflux extraction twice, each extraction for 2 hours to obtain the extract and medicinal residue I, and then filter the extract, the obtained filtrate I was concentrated after recovering ethanol to obtain thick paste I;

[0021] (4) Add the earthworm prepared in step (1) with 10 times the mass of water and decoct for 2 hours, then filter to obtain medicinal residues II and filtrate II, mix medicinal residues II with medicinal residues I, and then add 8 time...

Embodiment 2

[0024] (1) Prepare materials according to the following components by mass: 5 parts of Panax notoginseng, 20 parts of Rhodiola rosea, and 10 parts of Dilong;

[0025] (2) Grinding 1 / 2 of the notoginseng prepared in step (1) to a fine powder with a particle size of 120 mesh;

[0026] (3) Mix the remaining part of Panax notoginseng prepared in step (1) with Rhodiola rosea for coarse crushing until the particle size is 20 mesh, and then use 6 mass times and 3 mass times of ethanol with a concentration of 70v / v% respectively for Reflux extraction for 2 times, each extraction for 4 hours to obtain the extract and dregs I, and then filter the extract, the obtained filtrate I was concentrated after recovering ethanol to obtain a thick paste I;

[0027] (4) Add the earthworm prepared in step (1) with 12 times the mass of water and decoct for 3 hours, then filter to obtain medicinal residues II and filtrate II, mix medicinal residues II with medicinal residues I, and then add 6 times t...

Embodiment 3

[0030] (1) Prepare materials according to the following components by mass: 6 parts of Panax notoginseng, 30 parts of Rhodiola rosea, 12 parts of Dilong;

[0031] (2) Grinding 1 / 2 of the notoginseng prepared in step (1) to a fine powder with a particle size of 60 mesh;

[0032] (3) Mix the remaining part of Panax notoginseng prepared in step (1) with Rhodiola rosea for coarse crushing to a particle size of 40 mesh, and then use 10 mass times and 8 mass times of ethanol with a concentration of 70v / v% respectively for Reflux extraction for 2 times, each extraction for 3 hours to obtain the extract and medicinal residue I, and then filter the extract, and then concentrate the obtained filtrate I to obtain thick paste I after recovering ethanol;

[0033] (4) Add the earthworm prepared in step (1) with 8 times the mass of water and decoct for 1 hour, then filter to obtain medicinal residues II and filtrate II, mix medicinal residues II with medicinal residues I, and then add 10 tim...

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Abstract

The invention provides a traditional Chinese medicine composition for treating a chronic hypoxic pulmonary disease and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition comprises the following ingredients in parts by mass: 3-6 parts of panax notoginseng, 20-30 parts of rhodiola rosea and 10-15 parts of lumbricus. The preparation method comprises the steps of grinding a part of panax notoginseng, mixing the rest of panax notoginseng with the rhodiola rosea for coarse grinding, carrying out reflux extraction with alcohol to form extract and dreg I, after filtering the extract, condensing filtrate I with alcohol to form thick paste I, decocting the lumbricus with water to form dreg II and filtrate II, mixing the dreg II and the dreg I, then adding water for decocting, filtering to form filtrate III, after merging the filtrate II and the filtrate III, condensing to form thick paste II, mixing the thick paste I and the thick paste II, adding panax notoginseng fine powder after drying, mixing and grinding to form the traditional Chinese medicine composition for treating the chronic hypoxic pulmonary disease. The composition can improve a cardio-pulmonary function and improve survival quality, and has the advantages of quick effectiveness, obvious effect, high safety, simple and convenient preparation method and the like.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating chronic hypoxic pulmonary diseases and a preparation method thereof, belonging to the technical field of biomedicine. Background technique [0002] hypoxia-associated pulmonary hypertension (Hypoxia pulmonay hypertension, HPH) It is due to the imbalance of various vasomotor factors synthesized and secreted by the vascular endothelium after the damage of vascular endothelial cells caused by hypoxia, leading to early pulmonary vasoconstriction (HPV) and later pulmonary vascular remodeling (HPSR). It is a key link in the process of chronic obstructive pulmonary disease (COPD) and chronic cor pulmonale (CCP), and affects the development and prognosis of COPD and CCP. [0003] Chronic hypoxic pulmonary disease is a common clinical disease, frequently-occurring disease, high prevalence, heavy disease burden. Epidemiology shows: chronic obstructive pulmonary disease in people o...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/41A61P11/00A61P9/12A61K35/62
CPCA61K35/62A61K36/258A61K36/41A61K2236/15A61K2236/333A61K2236/39A61K2300/00
Inventor 付义余晓玲魏丹霞杨春艳张爱华刘青胡志宇
Owner 昆明市中医医院
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