A traditional Chinese medicine effective component composition for preventing and treating fatty liver

An active ingredient, fatty liver technology, applied in the direction of drug combination, ketone active ingredients, medical preparations containing active ingredients, etc., can solve the problems of less research and no involvement in compound prescriptions, and achieve significant prevention and treatment effects, safe and effective effects. effects of matter

Inactive Publication Date: 2017-03-29
NINGBO NO 2 HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0020] 3. Defects or deficiencies in the process, method, and performance of the existing background technology (necessity and significance of compound research on effective components of traditional Chinese medicine)
[0023] However, there are still relatively few compound researches based on the active ingredients of traditional Chinese medicine, and they have not been involved in many complex disease fields.

Method used

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  • A traditional Chinese medicine effective component composition for preventing and treating fatty liver
  • A traditional Chinese medicine effective component composition for preventing and treating fatty liver
  • A traditional Chinese medicine effective component composition for preventing and treating fatty liver

Examples

Experimental program
Comparison scheme
Effect test

experiment approach 2

[0050] Experimental scheme 2-Validation experiment of effective ingredient formula

[0051] 1. Model Preparation

[0052] Fatty liver model of rats with high-fat diet (induced by dietary factors alone), fed with high-fat diet (10% lard + 2% cholesterol + 88% basal feed) for 12 weeks, and the feed was produced by Shanghai Slack Experimental Animal Co., Ltd.

[0053] 2. Reagents and Drugs

[0054]Free fatty acid (FFA) enzyme-linked immunosorbent assay kit was purchased from Shanghai JiMian Biotechnology Co., Ltd., batch number: DRY1198-201306; triglyceride (triglyceride, TG) kit was purchased from Beijing Beihua Kangtai Clinical Reagent Co., Ltd. , batch number: 006304; total cholesterol (total cholesterol, TC) kit was purchased from Beijing Beihua Kangtai Clinical Reagent Co., Ltd., batch number: 006301. Serum alanine aminotransferase (ALT), aspartate aminotransferase (AST) kits were purchased from Nanjing Jiancheng Bioengineering Company, batch number: 20130724; salidroside ...

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PUM

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Abstract

Disclosed is a traditional Chinese medicine effective component compound for preventing and treating fatty liver. The traditional Chinese medicine effective component compound is characterized in comprising salidroside, gypenosides, curcumin and bighead atractylodes rhizome polysaccharide, wherein the ratio of each component is 4-10 parts of salidroside, 15-20 parts of gypenosides, 3-8 parts of curcumin and 65-75 parts of bighead atractylodes rhizome polysaccharide. Dosage forms of the traditional Chinese medicine effective component compound for preventing and treating fatty liver comprise tablets, capsules, pills, oral liquid or suspensions. The traditional Chinese medicine effective component compound for preventing and treating fatty liver in the invention is safe and effective, has definite active substances, and has more significant effect on preventing and treating fatty liver compared with a component compound containing a single component and Western medicine of polyene phosphatidylcholine capsule.

Description

technical field [0001] The invention relates to a medicine for preventing and treating fatty liver, in particular to a traditional Chinese medicine effective component composition for preventing and treating fatty liver. Background technique [0002] 1. Basic overview of existing product technology: [0003] (1) Epidemiology, pathogenesis and current status of Western medicine treatment of non-alcoholic fatty liver [0004] Nonalcoholic fatty liver disease (NAFLD) refers to a clinicopathological syndrome characterized by diffuse bullous steatosis in hepatocytes, which is caused by alcohol and other definite liver damage factors. In recent years, as the pathological manifestation of metabolic diseases in the liver, it has become the target of close clinical monitoring and research. Cirrhosis and even hepatocellular carcinoma. Fat accumulation in the liver exceeds 5% due to various reasons or more than 1 / 3 of unit liver cells have fat droplets in liver biopsy, which is call...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/715A61K36/424A23L33/00A61P1/16A61K31/12A61K31/7032
Inventor 李红山
Owner NINGBO NO 2 HOSPITAL
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