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Externally applied compound montmorillonite and sucrose powder as well as preparation method and application thereof

A technology of compound montmorillonite and external powder is applied in the field of medicine to achieve the effects of reducing exudation, good blood circulation and promoting cell regeneration

Inactive Publication Date: 2015-06-17
SHANDONG SBOND PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, the montmorillonite sucrose topical medicine that is specially used in the treatment of skin ulcers (decubitus ulcers, burn ulcers, calf ulcers) has not been reported yet.

Method used

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  • Externally applied compound montmorillonite and sucrose powder as well as preparation method and application thereof
  • Externally applied compound montmorillonite and sucrose powder as well as preparation method and application thereof
  • Externally applied compound montmorillonite and sucrose powder as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0146] Embodiment 1: Preparation of compound montmorillonite sucrose powder for external use

[0147] 1. The proportion of raw and auxiliary materials (w / w):

[0148] Montmorillonite 20 parts

[0149] 70 parts of sucrose

[0150] 10 parts of hydroxypropyl cellulose

[0151] 2. Prepare as follows:

[0152] (1) take by weighing montmorillonite, sucrose, hydroxypropyl cellulose for subsequent use by proportioning;

[0153] (2) Put the montmorillonite into a dry heat sterilizing cabinet at a temperature of 250°C for 120 minutes, and lower it to room temperature for later use;

[0154] (3) Get sucrose and hydroxypropyl cellulose, mix and pulverize, and cross a 325-mesh medicinal sieve for subsequent use;

[0155] (4) The material in step (3) is sterilized in an ethylene oxide sterilizer, the temperature is 40°C; the pressure is 35Kpa, the sterilization time is 3h, and it is used for standby;

[0156] (5) In the aseptic area, put the materials in step (2) and step (4) into a mix...

Embodiment 2

[0159] Embodiment 2: Preparation of compound montmorillonite sucrose powder for external use

[0160] 1. The proportion of raw and auxiliary materials (w / w):

[0161] Montmorillonite 25 parts

[0162] 90 parts of sucrose

[0163] 12 parts of hydroxypropyl cellulose.

[0164] 2. Prepare as follows:

[0165] (1) take by weighing montmorillonite, sucrose, hydroxypropyl cellulose for subsequent use by proportioning;

[0166] (2) Put the montmorillonite in a dry heat sterilizing cabinet at a temperature of 350° C. for 120 minutes, and drop it to room temperature for later use;

[0167] (3) Get sucrose and hydroxypropyl cellulose, mix and pulverize, and cross a 325-mesh medicinal sieve for subsequent use;

[0168] (4) The material in step (3) is sterilized in an ethylene oxide sterilizer, the temperature is 60°C; the pressure is 50Kpa, the sterilization time is 4h, and it is used for standby;

[0169] (5) In the aseptic area, put the materials in step (2) and step (4) into a m...

Embodiment 3

[0172] Embodiment 3: Preparation of compound montmorillonite sucrose powder for external use

[0173] 1. Prepare (w / w) as follows:

[0174] Montmorillonite 23 parts

[0175] 80 parts of sucrose

[0176] Hydroxypropyl cellulose 11 parts.

[0177] 2. Prepare as follows:

[0178] (1) take by weighing montmorillonite, sucrose, hydroxypropyl cellulose for subsequent use by proportioning;

[0179] (2) Put the montmorillonite into a dry heat sterilizer, sterilize at 300°C for 120 minutes, and lower it to room temperature for later use;

[0180] (3) Get sucrose and hydroxypropyl cellulose, mix and pulverize, and cross a 325-mesh medicinal sieve for subsequent use;

[0181] (4) The material in step (3) is sterilized in an ethylene oxide sterilizer, the temperature is 50°C; the pressure is 40Kpa, the sterilization time is 3h, and it is used for standby;

[0182] (5) In the aseptic area, put the materials in step (2) and step (4) into a mixer for mixing to obtain the product;

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Abstract

The invention relates to externally applied compound montmorillonite and sucrose powder for treating skin ulcers and a preparation method and application thereof. The externally applied powder is prepared from the following raw materials in parts by mass: 20-30 parts of montmorillonite, 70-100 parts of sucrose and 10-13 parts of hydroxypropyl cellulose. The preparation method of the externally applied compound montmorillonite and sucrose powder for treating skin ulcers, disclosed by the invention, comprises the following steps: by taking montmorillonite and sucrose as effective components and medicinal auxiliary materials, performing dry heat sterilization on montmorillonite, performing ethylene oxide sterilization on sucrose and hydroxypropyl cellulose, and then mixing, and carrying out processes such as sterile sub-packaging to prepare a medicament. The invention also provides an application of the medicament in preparation of medicines for treating skin ulcers. The compound montmorillonite and sucrose external powder, disclosed by the invention, is applied externally through skin and has relatively good treatment effects on skin ulcers at different periods.

Description

technical field [0001] The invention relates to a compound preparation and its preparation method and application, in particular to a compound montmorillonite sucrose powder for external use for treating skin ulcers and its preparation method and application, belonging to the technical field of medicine. Background technique [0002] Chronic skin ulcers, also known as refractory ulcers, are common refractory diseases, including vascular ulcers, compression ulcers, radiation ulcers, and infectious ulcers. It brings great pain to patients physically and mentally, so it has attracted widespread attention from scholars, and a lot of research has been done on both traditional Chinese medicine and Western medicine. [0003] Skin ulcers can be divided into trauma infection, pressure ulcers, venous ulcers, diabetic ulcers, etc. according to different pathogenic factors. In terms of the population, chronic refractory wounds on the body surface caused by trauma are mainly young and m...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/06A61K9/14A61K47/26A61K47/38A61P17/02
Inventor 乔敏
Owner SHANDONG SBOND PHARMA
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