A kind of traditional Chinese medicine sugar-free granule for treating pelvic inflammatory disease
A technology of pelvic inflammatory disease and granules, which is applied in the directions of drug combinations, pharmaceutical formulations, and medical preparations containing active ingredients, etc., can solve the problems of unsuitable use of granules, inducing diabetes, and dental caries in children, achieving good palatability and expanding suitable use. Population, the effect of reducing blood viscosity
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Embodiment 1
[0032] 1) Take 400g of a little red, 200g of Hedyotis diffusa, 400g of Peach Blossom, 200g of white back leaf root, 200g of 菥蓂, 300g of Mildew Spatholobus, 400g of myrtle root;
[0033] 2) Decoct the above seven flavors with water for 3 times, each extraction time is 3 hours, 2 hours, 1 hour, combine the decoction, filter, and concentrate the filtrate to a clear paste with a relative density of 1.05 at 70°C; put it at room temperature Add ethanol to make the alcohol content 50%, stir evenly, let it stand for 24 hours, filter, recover ethanol from the filtrate to an extract with a relative density of 1.20 at 70°C;
[0034] 3) After mixing 50g soluble starch and 20g macroporous ion exchange resin Amberlite IRC 64, put it into the fluidized bed granulation chamber of the spray drying granulator for preheating;
[0035] 4) 30g of soluble starch is added with water to make a 20% starch solution, and the extract obtained in step 2) is added, stirred evenly, added to a preheated flui...
Embodiment 2
[0038] 1) Take 600g of a little red, 400g of Hedyotis diffusa, 600g of Peach Blossom, 400g of white back leaf root, 400g of 菥蓂, 500g of Mildew Spatholobus, and 600g of myrtle root;
[0039] 2) The above seven flavors are decocted twice with water, and the extraction time is 3 hours and 2 hours each time. The decoctions are combined and filtered. The alcohol content is 80%, stir evenly, stand still for 24 hours, filter, the extractant with relative density of 1.30 when the ethanol is recovered from the filtrate to 80°C;
[0040] 3) After mixing 70g soluble starch and 40g macroporous ion exchange resin Amberlite IRC 64, put it into the fluidized bed granulation chamber of the spray drying granulator for preheating;
[0041] 4) Add water to 50 g of soluble starch to make a 30% starch solution, add the extract obtained in step 2), stir well, add to a preheated fluidized bed granulation chamber, and spray dry to obtain granules.
[0042] In step 3) and step 4), the spray drying ad...
Embodiment 3
[0044] 1) Take 500g of a little red, 300g of Hedyotis diffusa, 500g of Peach Blossom, 300g of white back leaf root, 300g of 菥蓂, 400g of Miltonia Spatholobus, and 500g of myrtle root;
[0045] 2) Decoct the above seven flavors twice with water, the first time for 2 hours, and the second time for 1.5 hours, combine the decoction, filter, and concentrate the filtrate to a clear paste with a relative density of 1.20 at 80°C; add ethanol after it is cooled to room temperature Make the alcohol content 65%, stir evenly, let stand for 24 hours, filter, the extractant whose relative density is 1.25 when the ethanol is recovered from the filtrate to 80 ℃;
[0046] 3) After mixing 60g soluble starch and 30g macroporous ion exchange resin Amberlite IRC 64, put it into the fluidized bed granulation chamber of the spray drying granulator for preheating;
[0047] 4) 40 g of soluble starch is added with water to make a 25% starch solution, and the extract obtained in step 2) is added, stirred...
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