Anti-bacteria anti-itch gel and preparation method

A gel and triclosan technology, applied in the field of medical gel, can solve the problems of patients with large side effects and poor bacteriostatic properties, and achieve the effects of less toxic side effects, preventing skin dryness, and maintaining relative moisture.

Inactive Publication Date: 2015-10-28
HENAN HUIBO MEDICAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] For the shortcomings of the current antipruritic products proposed above, the purpose of the present invention is to develop an antibacterial antipruritic gel and a preparation method, which can solve the problem of poor antibacterial performance and relatively large side effects on patients in previous antipruritic products. and other defects to meet the needs of the majority of patients

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] An antibacterial and antipruritic gel of the present invention, the antibacterial and antipruritic gel comprises the following raw materials in mass percentage: ethanol: 4%; carbomer: 0.75%; medical glycerin: 2%; azone: 1% ; Triclosan: 0.4%; Triclosan solubilizer: 1.6%; Water-soluble peppermint oil: 0.2%; Triethanolamine: 2.86%; Pure water: 87.19%.

[0033] The present invention is used for the method for preparing above-mentioned antibacterial and antipruritic gel, and described method comprises the following steps:

[0034] 1) Weigh each component according to the specified mass percentage;

[0035] 2) For the preparation of the gel matrix: dissolve carbomer into pure water in proportion, and wait for its swelling to be complete, that is, the corresponding gel matrix is ​​prepared;

[0036] 3) Add medical glycerin to the gel matrix and stir thoroughly, then add azone, then add ethanol and water-soluble peppermint oil, finally add triclosan and triclosan solubilizer, ...

Embodiment 2

[0040] An antibacterial and antipruritic gel of the present invention, the antibacterial and antipruritic gel comprises the following raw materials in mass percentage: ethanol: 3%; carbomer: 1%; medical glycerin: 1.5%; azone: 0.6% ; Triclosan: 0.3%; Triclosan solubilizer: 1.2%; Water-soluble peppermint oil: 0.15%, Triethanolamine: 2.5%; Pure water: 89.75%.

[0041] The preparation method of the antibacterial and antipruritic gel of this embodiment is the same as that of Example 1, wherein triethanolamine is used to adjust the pH value of the antibacterial and antipruritic gel to 5.5.

Embodiment 3

[0043]An antibacterial and antipruritic gel of the present invention, the antibacterial and antipruritic gel comprises the following raw materials in mass percentage: ethanol: 5%; carbomer: 0.5%; medical glycerin: 2.5%; azone: 1.4% ; Triclosan: 0.5%; Triclosan solubilizer: 2%; Water-soluble peppermint oil: 0.25%; Triethanolamine: 3.5%; Purified water: 84.35%.

[0044] The preparation method of the antibacterial and antipruritic gel of this embodiment is the same as that of Example 1, wherein triethanolamine is used to adjust the pH value of the antibacterial and antipruritic gel to 7.5.

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PUM

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Abstract

The invention discloses an anti-bacteria anti-itch gel and a preparation method thereof. The anti-bacteria anti-itch gel comprises the following raw materials: ethyl alcohol, carbomer, medical glycerol, azone, triclosan, a triclosan solubilizer, water-soluble mint oil, triethanolamine and pure water. The preparation method for the anti-bacteria anti-itch gel comprises the following steps: weighing the components according to the specified weight percentage; preparing a gel substrate: dissolving carbomer into pure water according to proportion to obtain the corresponding gel substrate after the carbomer is completely swelled; adding medical glycerol into the gel substrate, fully stirring, then adding azone, adding ethyl alcohol and water-soluble mint oil, and finally adding triclosan and the triclosan solubilizer so as to preliminarily prepare the anti-bacteria anti-itch gel; finally adding triethanolamine to adjust the pH value of the anti-bacteria anti-itch gel so as to obtain the final anti-bacteria anti-itch gel.

Description

technical field [0001] The invention belongs to the technical field of medical gels, in particular to an antibacterial and antipruritic gel and a preparation method thereof. Background technique [0002] Skin pruritus belongs to neuropsychiatric skin disease and is a kind of skin neurosis disease. Itchy skin may cause patients to scratch the itchy place, resulting in scars on the skin, which affects the appearance and brings distress to people. Repeated scratching can lead to virus or bacterial infection in the wound, thereby affecting people's health. Long-term skin itching can also make people unable to concentrate, and has many negative effects on sleep and mood. Therefore, skin diseases such as skin itching have gradually attracted more and more attention and research. [0003] The causes of skin itching can be roughly divided into two aspects, one is internal factors, which mainly include mental stress and increased skin temperature, and the other is external factors, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/534A61K9/06A61K47/32A61P31/04A61P17/04A61K31/085
Inventor 朱天钢刘尧黄宁
Owner HENAN HUIBO MEDICAL CO LTD
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