Drug for preventing and curing shiver after intraspinal anesthesia and preparation method thereof

A post-anesthesia shivering and drug technology, which is applied in the field of traditional Chinese medicine, can solve the problems of patients with stasis and accumulation, and achieve remarkable effects, no toxic side effects, and the effect of relieving shivering

Inactive Publication Date: 2015-10-28
JINAN SHUNHAO BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0019] At present, there are relatively many drugs to prevent chills in patients after spinal anesthesia. Although these drugs have a certain effect on inhibiting ch

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0072] Example 1 Injection

[0073] Recipe: 12g deerbite grass, 22g Morinda officinalis, 10g sea dragon, 12g ginseng, 16g chicken kidney grass, 9g Cynomorium, 12g donkey kidney, 12g earth palm root, 22g clove, 2g one-leaf hagi, 12g black medicine, Gorgon fruit 13g, lily 18g, Xuanjing stone 8g, heart not dry 2g, spider incense 8g, dried ginger 17g, angelica dahurica 12g, yellow water twig 18g, perilla leaf 13g, houttuynia cordata 10g, plow grass 13g, licorice 17g, ground 12g of elm, 13g of astragalus, 17g of Acanthopanax, 12g of Fangfeng, 18g of grass fruit and 13g of ephedra root.

[0074] Its preparation method is:

[0075] In the first step, the raw medicinal materials are mixed in proportion, put into an ultrafine pulverizer and pulverized into a mixed powder composed of micron-sized particles with a volume average particle size of 1 μm and nano-sized particles with a volume average particle size of less than 0.1 μm , the powder yield of the mixed powder is at least 97%; ...

Embodiment 2

[0078] Embodiment 2 decoction

[0079] Recipe: 12g of Deerbitum, 22g of Morinda officinalis, 12g of Sea Dragon, 12g of Huanyangshen, 18g of Chicken Kidney Grass, 9g of Cynomorium, 12g of Donkey Kidney, 12g of Dadiba Root, 16g of Clove, 2g of Hagi, 14g of Wuyao, 12g Gorgon fruit, 16g lily, 8g Xuanjing stone, 2g Xinbugan, 7g spider incense, 18g dried ginger, 15g Angelica dahurica, 17g yellow water branch, 12g perilla leaf, 12g Houttuynia cordata, 14g licorice, 17g licorice, ground 12g of elm, 18g of astragalus, 16g of Acanthopanax, 12g of Fangfeng, 22g of Huangbeicaoguo and 15g of ephedra root.

[0080] Its preparation method is:

[0081] Step 1: Mix the raw materials and medicinal materials into a purple casserole, add water until the water soaks the upper surface of the medicinal materials by 4cm, soak for 5 hours; Fry for 45 minutes until the dosage of the medicinal liquid is 150ml, filter to obtain the filtrate a, and set aside; Step 3: Add the remaining medicinal residues...

Embodiment 3

[0082] Embodiment 3 oral liquid

[0083] Recipe: 16g deerbite, 18g Morinda officinalis, 9g sea dragon, 12g ginseng, 17g chicken kidney grass, 8g cynomorium, 9g donkey kidney, 14g earth palm root, 22g clove, 2g one leaf hagi, 7g black medicine, Gorgon fruit 13g, lily 19g, Xuanjing stone 8g, heart not dry 2g, spider incense 8g, dried ginger 15g, angelica dahurica 8g, yellow water twig 17g, perilla leaf 13g, houttuynia cordata 12g, plow grass 16g, licorice 17g, ground 9g of elm, 17g of astragalus, 18g of Acanthopanax, 13g of Fangfeng, 16g of huangbeicaoguo and 18g of ephedra root.

[0084] Its preparation method is:

[0085] The first step is to mix Yangshen, Gallinarum and Cynomorium in proportion, use methanol with an alcohol concentration of 85% as a solvent, and use the percolation method to slowly percolate at a rate of 2ml per minute, and collect the percolation liquid. Concentrate under reduced pressure and dry to obtain a dry paste, which is pulverized into powder, and ...

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Abstract

The invention discloses a drug for preventing and curing shiver after intraspinal anesthesia and a preparation method thereof. The drug is prepared from the following medicinal materials: Chinese pyrola herb, medicinal indianmulberry roots, sea otter, Crepis rigescens Diels, Habenria petelotii Gagnep., cynomorium songaricum, donkey kidney, Curculigo capitulata root, clove, securinega suffruticosa, radix linderae, Gordon euryale seed, lily, selenitum, Tupistra pachynema Wang et Tang, Valeriana jatamansi, rhizoma zingiberis, radix angelicae, Tiarella polyphylla, folia perillae acutae, Houttuynia cordata, japanese violet herb or root, liquorice, garden burnet, astragalus, acanthopanax, divaricate saposhnikovia root, Themeda triandra fruit and ephedra herb root. The drug has the beneficial effects of being capable of preventing and curing shiver after intraspinal anesthesia and well relieving shiver symptoms fundamentally, treating both symptoms and root causes, eliminating and relieving the shiver phenomenon after intraspinal anesthesia, and being free of toxic and side effects and remarkable in effect.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a medicine for preventing and treating chills after intraspinal anesthesia and a preparation method thereof. Background technique [0002] Some scholars have pointed out that the probability of chills in patients undergoing anesthesia ranges from 5% to 65%, and the probability of chills in patients undergoing general anesthesia is higher than that in patients undergoing spinal anesthesia. When the patient has chills during anesthesia, it will not only lead to increased intracranial pressure and intraocular pressure, but also increase the patient's oxygen consumption and body metabolism. Patient The reasons why patients experience chills during anesthesia are as follows. [0003] 1 Influencing factors [0004] 1.1 Thermoregulation mechanism [0005] The human body's thermoregulation mechanism mainly includes three parts: efferent neural pa...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61P43/00A61K33/06A61K35/60A61K35/48
Inventor 密夫丽杜国强
Owner JINAN SHUNHAO BIOTECH CO LTD
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