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Application of callicarpa plant extract

A plant extract, a technology of the genus Rhizoma, which is applied in the directions of cosmetic preparations, preparations for skin care, cosmetics, etc., can solve the problems of freckle removal, whitening, wrinkle removal, sun protection or anti-aging, etc.

Active Publication Date: 2015-11-25
SUZHOU NEUPHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For this reason, people use various anti-aging cosmetics, mainly by adding antioxidants (such as SOD, vitamin E, etc.) to directly exert anti-oxidative effects. This type of cosmetics has certain anti-aging effects, but most of them cannot effectively solve the above-mentioned skin problems question
At present, there is no report on the application of plants of the genus Amethyst in freckle removal, whitening, wrinkle removal, sun protection or anti-aging functional cosmetics

Method used

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  • Application of callicarpa plant extract
  • Application of callicarpa plant extract
  • Application of callicarpa plant extract

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0062] The dried leaves of Callicarpacathayana H.T.Chang were crushed to the coarsest powder, and extracted by percolation with 90% ethanol at a flow rate of 1 mL / h per gram of dried leaf powder of Callicarpacathayana H.T.Chang for 10 h. The percolation liquid is collected, and the percolation liquid is concentrated under reduced pressure to remove ethanol, and the volume of the concentrated liquid is equivalent to the amount of medicinal materials. Add double the volume of water, let it stand overnight, and centrifuge to obtain the supernatant. Make the supernatant pass through the D101 macroporous adsorption resin column, wash the impurities with water of 6 times the bed volume of the resin column, discard the washing solution, and then elute with 40% ethanol of 3 times the bed volume of the resin column, collect eluent. The eluate was concentrated under reduced pressure to remove ethanol. Dilute the concentrated solution with water to the volume of the initial supernatant...

Embodiment 2

[0064] Crush the dried stems and leaves of Callicarpacathayana H.T.Chang to the coarsest powder, add 12 times the amount (that is, 12ml / g dried stems and leaves of Callicarpacathayana H.T.Chang) of 80% ethanol, and flash extract for 3 minutes , extract twice, combine the extracts, concentrate under reduced pressure to remove ethanol, the volume of the concentrate is equivalent to the amount of medicinal materials. Add double the volume of water, let it stand overnight, and centrifuge to obtain the supernatant. Make the supernatant pass through the D101 macroporous adsorption resin column, wash with water of 6 times the bed volume of the resin column, discard the washing solution, elute with 30% ethanol of 3 times the bed volume of the resin column, and collect the eluted liquid. The eluate was concentrated under reduced pressure to remove ethanol. Dilute the concentrated solution with water to the volume of the initial supernatant, then pass through the polyamide chromatogra...

Embodiment 3

[0066] Crush the dried leaves of Callicarpaformosana Rolfe to the coarsest powder, add 12 times the amount (ie, 12ml / g dry leaf powder of Callicarpaformosana Rolfe) of 70% ethanol, and perform flash extraction for 3 minutes, and the extraction times are 2 times. Combine the two extracts, concentrate the extract under reduced pressure to remove ethanol, and the volume of the concentrate is equivalent to the amount of medicinal materials. Add double the volume of water, let it stand overnight, and centrifuge to obtain the supernatant. Make the supernatant pass through the D101 macroporous adsorption resin column, wash with water of 6 times the bed volume of the resin column, discard the washing solution, elute with 30% ethanol of 4 times the bed volume of the resin column, and collect the eluted liquid. Concentrate the eluent under reduced pressure and dry to obtain the extract of Rhododendron flower leaf as a tan uniform powder.

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Abstract

The invention provides application of callicarpa plant extract in preparation of cosmetics used for removing freckles, whitening skin, removing wrinkles, protection from sun or preventing aging. The callicarpa plant extract has functions of suppressing activity of tyrosinase, clearing free radicals, reducing ultraviolet absorption and resisting skin aging. Callicarpa plants are extensive in source, long in using history and simple in extract preparation process. The callicarpa plant extract is a cosmetic functional raw material which is economically affordable, safe and effective. The invention further provides the cosmetics prepared by the callicarpa plant extract.

Description

technical field [0001] The invention relates to the field of cosmetics, in particular to the use of plant extracts from the genus Asteraceae in preparing cosmetics. Background technique [0002] The skin is the largest organ and tissue of the human body, which can protect the body from harmful external factors (such as ultraviolet rays, chemical irritants, heavy metals, and some exogenous pollutants). In addition to the natural function degradation brought about by age, factors such as modern fast-paced, high-stress lifestyles, unrestrained diet, and environmental deterioration have accelerated the degradation and aging of skin functions, leading to a series of skin problems. [0003] Modern research believes that the human body will produce excessive active oxygen free radicals during the metabolic process. If it is not removed in time, it will cause oxidative damage to the skin, resulting in skin aging, degeneration, relaxation, loss of elasticity, and wrinkles. Therefore...

Claims

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Application Information

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IPC IPC(8): A61K8/97A61Q19/02A61Q17/04A61Q19/08
Inventor 刘敬阁程屹俊曹进国朱永亮钱向平
Owner SUZHOU NEUPHARMA
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