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Vine tea chewable tablets facilitating dissolution of effective constituents and preparing method of vine tea chewable tablets

A technology of chewable tablets and vine tea, which is applied in the field of preparation of vine tea chewable tablets, can solve the problems of affecting patients' enthusiasm for taking medicine, sticky mouth and spicy feeling, and not good enough taste, so as to overcome the inconvenience of taking, facilitate dissolution, and improve appearance. smooth effect

Inactive Publication Date: 2015-12-09
GUANGXI UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The operation of this patented method is relatively complicated. Although the disintegration degree of the produced tablet meets the disintegration time limit of the pharmacopoeia dispersible tablet, it is found that the surface of the tablet is easy to powder during use, the taste is not good enough, and it has a sticky and spicy feeling. Affect the enthusiasm of patients to take medicine

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Take 1kg of processed vine tea, add 15L of water, decoct and extract twice, each time for 1 hour, combine the filtrate twice, concentrate to 6-7L, after standing for 48 hours, filter out the precipitated yellow-white precipitate, and store at 60°C Dried, powdered, and crossed a 200-mesh sieve to obtain 284 grams of rattan tea powder.

[0023] Get pregelatinized starch 159g, microcrystalline cellulose 100g, pulverize and sieve, and fully mix with above-mentioned rattan tea powder 200g; Dissolve 25g povidone K30 in 250ml dehydrated alcohol, make povidone K30 concentration: 10% absolute ethanol solution, dissolve 1 gram of sucralose in it, add the above-mentioned vine tea powder and auxiliary material powder that have been mixed uniformly to make a soft material, pass through a 24-mesh sieve to make wet granules, and dry in an oven at 60°C for 90 minutes Finally, take it out and pass through a 24-mesh sieve, granulate, add 15 grams of magnesium stearate and mix evenly, sen...

Embodiment 2

[0025] Take 1kg of processed vine tea, add 12L of water, decoct and extract twice, each time for 1 hour, combine the filtrate twice, concentrate to 6-7L, after standing for 48 hours, filter out the precipitated yellow-white precipitate, and store at 80°C Dried, powdered, and passed through a 200-mesh sieve to obtain 278 grams of rattan tea powder.

[0026] Get pregelatinized starch 184g, microcrystalline cellulose 90g, pulverize and sieve, and fully mix with above-mentioned rattan tea powder 200g; Dissolve 15g povidone K30 in 300ml dehydrated alcohol, make povidone K30 concentration: 5% absolute ethanol solution, dissolve 1 gram of sucralose in it, add the above-mentioned vine tea powder and auxiliary material powder that have been mixed uniformly to make soft material, pass through a 24 mesh sieve to make wet granules, and dry in an oven at 60°C for 90 minutes Finally, take it out and pass through a 24-mesh sieve, granulate, add 10 grams of magnesium stearate and mix evenly, ...

Embodiment 3

[0028] Take 1kg of processed vine tea, add 15L of water, decoct and extract twice, each time for 1 hour, combine the filtrate twice, concentrate to 6-7L, after standing for 48 hours, filter out the precipitated yellow-white precipitate, and store at 60°C Dry, powder, and pass through a 200-mesh sieve to obtain 281 grams of rattan tea powder.

[0029] Get 83g of pregelatinized starch, 125g of microcrystalline cellulose, and fully mix with 200g of the above-mentioned rattan tea powder; 25g of povidone K30 is dissolved in 250ml of absolute ethanol to make povidone K30 concentration of 10% anhydrous Ethanol solution, dissolve 2 grams of sucralose and 0.3 grams of strawberry essence in it, add the above-mentioned vine tea powder and auxiliary material powder that have been mixed uniformly to make soft materials, pass through a 24-mesh sieve to make wet granules, and dry in an oven at 60°C for 90 minutes Finally, take it out and pass through a 24-mesh sieve, granulate, add 15 grams ...

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Abstract

The invention provides vine tea chewable tablets facilitating dissolution of effective constituents and a preparing method of the vine tea chewable tablets. Vine tea powder serves as main materials of the vine tea chewable tablets, specific accessories and corrigent serve as auxiliary materials, the taste of medicine is improved while the medical effect is guaranteed, and the used accessories and the corrigent are edible food additives, and no harm is caused to human bodies. The extracting and preparing method and the preparation technology of the vine tea powder are simple, convenient and easy to implement, the production cost is low, and the yield is high; the obtained vine tea chewable tablets have the advantages that the appearance is smooth, the color and luster are even and bright, stability is good, the taste is moderate, the dissolving speed is high, effective ingredients are dissolved out easily, bioavailability is high, and the tablets are convenient to eat and carry and can be eaten without being brewed; the tablets further achieve a good function of assisting in lowering blood fat.

Description

technical field [0001] The invention belongs to the field of pharmaceutical preparations, and in particular relates to a vine tea chewable tablet which facilitates the dissolution of active ingredients and a preparation method thereof, in particular to a preparation method of a vine tea chewable tablet with the function of assisting in lowering blood fat. Background technique [0002] Vine tea, also known as sweet tea vine; Its medicinal use was first seen in "Caomu Bianfang" written by Liu Shanshu in the Qing Dynasty. It is processed from the tender stems and leaves of Ampelosis grossedentata (Hand-Mazz) W.T.Wang. Its medicinal value, original plant, geographical distribution, etc. are recorded in large dictionaries such as "National Compilation of Chinese Herbal Medicine", "Selected Edition of Guangxi Materia Medica", "Chinese Materia Medica", "List of Medicinal Plants in Guangxi". At the same time, vine tea is also a folk herbal medicine used by many ethnic groups. It h...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/87A61K47/38A61K9/20A61P3/06
Inventor 覃洁萍奉艳花王淼黄志飘刘鹏飞刁宇常敬芳
Owner GUANGXI UNIV OF CHINESE MEDICINE
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