Traditional Chinese medicine composite for treating infantile asthma and preparation method thereof

A technology of children's asthma and composition, which is applied in the field of traditional Chinese medicine composition and its preparation for treating children's asthma, can solve the problem that the effect of promoting lung and relieving asthma is not very obvious, achieve better drug treatment effect, lower side effects, and solve the root cause of disease Effect

Inactive Publication Date: 2015-12-23
罗奕珺
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Chinese patent application 201310440498.9 discloses a pharmaceutical composition for treating asthma in children. The pharmaceutical composition includes the following raw materials: capillary, gardenia, flavescens, fritillaria, licorice, rhubarb, and chamomile. It has a certain effect of clearing away heat and dampness, reducing phlegm and relieving cough, but it is not very effective in sweating and dispelling cold, clearing lung and relieving asthma

Method used

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  • Traditional Chinese medicine composite for treating infantile asthma and preparation method thereof

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Experimental program
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Effect test

Embodiment 1

[0031] The traditional Chinese medicine composition of Example 1 of the present invention is prepared from the following raw materials in parts by weight: 15 parts of Ophiopogon japonicus, 5 parts of perilla leaves, 3 parts of almonds, 9 parts of tangerine peel, 9 parts of poria cocos, 6 parts of Chuanbei, and 5 parts of cinnamon , 3 parts of Araceae and 5 parts of licorice.

[0032] The preparation method is as follows: take Radix Ophiopogon japonicus, pulverize into a coarse powder, place it in a supercritical carbon dioxide extraction device, add a 75% ethanol solution with a volume fraction of 40% by weight of the coarse powder, control the flow rate of carbon dioxide to 15L / h, and extract the pressure to 20MPa, the extraction temperature is 45℃, the extraction time is 2h, and the Ophiopogon japonicus extract is obtained by decompression separation, and the Ophiopogon japonicus residue is retained; the perilla leaves, almonds, tangerine peel, poria cocos, Chuanbei, cinnamon...

Embodiment 2

[0034] The traditional Chinese medicine composition of Example 2 of the present invention is prepared from the following raw materials in parts by weight: 10 parts of Ophiopogon japonicus, 10 parts of perilla leaves, 10 parts of almonds, 5 parts of tangerine peel, 15 parts of poria cocos, 3 parts of Chuanbei, and 10 parts of cinnamon , 9 parts of Araceae and 10 parts of licorice.

[0035] The preparation method is as follows: take Radix Ophiopogon japonicus, pulverize into a coarse powder, place it in a supercritical carbon dioxide extraction device, add 30% of the weight of the coarse powder into an ethanol solution with a volume fraction of 70%, control the flow rate of carbon dioxide to 20L / h, and extract the pressure to 15MPa, the extraction temperature was 50°C, the extraction time was 2h, and the Ophiopogon japonicus extract was separated under reduced pressure, and the Ophiopogon japonicus residue was retained; perilla leaves, almonds, tangerine peel, poria cocos, Chuanb...

Embodiment 3

[0037] The traditional Chinese medicine composition of Example 3 of the present invention is prepared from the following raw materials in parts by weight: 20 parts of Ophiopogon japonicus, 8 parts of perilla leaves, 8 parts of almonds, 3 parts of tangerine peel, 12 parts of poria cocos, 9 parts of Chuanbei, and 8 parts of cinnamon , 6 parts of Araceae and 2 parts of licorice.

[0038] The preparation method is similar to Example 1.

[0039] Clinical Observation

[0040] 1. Case selection: Among the 300 clinical volunteers with pediatric asthma, there were 150 boys and 150 girls, aged 3-10 years. There was no statistical difference in the course of disease.

[0041] 2. Diagnostic criteria:

[0042] (1) Diagnostic criteria of traditional Chinese medicine: According to the "Diagnosis and Curative Effect Criteria of Traditional Chinese Medicine Disease Syndrome", "Clinical Guidelines for New Drugs of Traditional Chinese Medicine" (2002) and "Advanced Series of Traditional Chine...

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Abstract

The invention belongs to the technical field of traditional Chinese medicine and relates to a traditional Chinese medicine composite for treating infantile asthma and a preparation method thereof. The traditional Chinese medicine composite is prepared from, by weight, 10-20 parts of radix ophiopogonis, 5-10 parts of perilla leaves, 3-10 parts of almonds, 2-9 parts of pericarpium citri reticulatae, 9-15 parts of poria cocos, 3-9 parts of fritillaria cirrhosa, 5-10 parts of cinnamon, 3-9 parts of arisaema heterophyllum and 1-10 parts of licorice roots. The traditional Chinese medicine composite has the effects of inducing perspiration, dispelling cold, freeing the lung, relieving asthma, expelling phlegm, relieving coughs, soothing the liver, relieving stagnant qi, clearing heat and moistening the lung, and the traditional Chinese medicine composite further has the advantages of being simple in preparation process, good in curative effect, low in side effect, convenient to take, easy to apply and popularize and the like.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating asthma in children and a preparation method thereof. Background technique [0002] Asthma in children is a common and frequently-occurring disease in childhood. It is a chronic airway morbid reactive disease involving eosinophils, mast cells, T lymphocytes and other inflammatory cells and cytokines. Most of the children who are weak in health or have phlegm in the lungs can be induced by the following factors: wind and cold. Mental stimulation and depression, or sudden changes in the environment, inhalation of dust and diet, etc. Because children are immature and have low disease resistance, they belong to the body of immature yin and immature yang. Most of them are mixed with cold and heat, and coexistence of deficiency and excess. Children's internal organs are not yet mature. Because the human skin is in c...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8968A61P11/06
Inventor 罗奕珺
Owner 罗奕珺
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