Application of traditional Chinese medicinal composition in preparing medicine for treating myocardial infarction

A composition and technology of traditional Chinese medicine, applied in the field of preparation of medicine for treating myocardial infarction, and the field of traditional Chinese medicine composition, can solve the problems such as the effect of nourishing qi and nourishing yin is not very significant, and achieve the effect of solving the root cause of the disease, low side effects, and simple preparation process

Inactive Publication Date: 2016-01-06
罗奕珺
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Chinese patent application 201410113088.8 discloses a traditional Chinese medicine composition for the treatment of myocardial infarction. It has a good therapeutic effect in the treatment of myocardial infarction and has significant clinical promotion value, but the effect in nourishing qi and nourishing yin, promoting blood circulation and removing blood stasis is not very significant

Method used

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  • Application of traditional Chinese medicinal composition in preparing medicine for treating myocardial infarction
  • Application of traditional Chinese medicinal composition in preparing medicine for treating myocardial infarction

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Effect test

Embodiment 1

[0032] The traditional Chinese medicine composition involved in the present invention is prepared from the following raw materials in parts by weight: 6 parts of Ophiopogon japonicus, 10 parts of Angelica sinensis, 6 parts of ground beetle, 15 parts of ginsenoside Rb, 12 parts of ginsenoside Rg, 5 parts of ginsenoside Rd, and 3 parts of ginsenoside Re3 6 parts of Chuanxiong, 3 parts of cinnamon and 8 parts of licorice.

[0033] Preparation method: Weigh Ophiopogon japonicus, crush it into a coarse powder, put it in a supercritical carbon dioxide extraction device, add 45% of the weight of the coarse powder and a 75% ethanol solution, adjust the flow rate of carbon dioxide to 20L / h, and the extraction pressure to 20MPa , the extraction temperature is 60°C, the extraction time is 2h, the Ophiopogon japonicus extract is separated under reduced pressure, and the Ophiopogon japonicus residue is retained; Angelica sinensis, wood beetle, Chuanxiong, cinnamon and licorice are weighed, ...

Embodiment 2

[0035] The traditional Chinese medicine composition involved in the present invention is prepared from the following raw materials in parts by weight: 15 parts of Ophiopogon japonicus, 4 parts of angelica, 4 parts of ground beetle, 12 parts of ginsenoside Rb, 18 parts of ginsenoside Rg, 3 parts of ginsenoside Rd, and ginsenoside Re2 3 parts of Chuanxiong, 8 parts of cinnamon and 3 parts of licorice.

[0036] Preparation method: Weigh Ophiopogon japonicus, crush it into a coarse powder, put it in a supercritical carbon dioxide extraction device, add 30% of the weight of the coarse powder into an 80% ethanol solution, adjust the flow rate of carbon dioxide to 15L / h, and the extraction pressure to 15MPa , the extraction temperature is 50°C, the extraction time is 2h, the Ophiopogon japonicus extract is obtained by decompression separation, and the Ophiopogon japonicus residue is retained; Angelica sinensis, wood beetle, Chuanxiong, cinnamon and licorice are weighed, the Ophiopogon...

Embodiment 3

[0038] The traditional Chinese medicine composition involved in the present invention is prepared from the following raw materials in parts by weight: 10 parts of Ophiopogon japonicus, 6 parts of angelica, 8 parts of ground beetle, 18 parts of ginsenoside Rb, 15 parts of ginsenoside Rg, 1 part of ginsenoside Rd, and 5 parts of ginsenoside Re5 10 parts of Chuanxiong, 5 parts of cinnamon and 5 parts of licorice.

[0039] Preparation method: Weigh Ophiopogon japonicus, crush it into a coarse powder, put it in a supercritical carbon dioxide extraction device, add 70% ethanol solution with a volume fraction of 40% of the weight of the coarse powder, adjust the flow rate of carbon dioxide to 18L / h, and the extraction pressure to 15MPa , the extraction temperature is 45°C, the extraction time is 2h, the Ophiopogon japonicus extract is separated under reduced pressure, and the Ophiopogon japonicus residue is retained; Angelica sinensis, wood beetle, Chuanxiong, cinnamon and licorice ar...

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Abstract

The invention belongs to the technical field of traditional Chinese medicine, and relates to application of a traditional Chinese medicinal composition in preparing a medicine for treating myocardial infarction. The traditional Chinese medicinal composition is prepared from the following raw materials in parts by weight: 6-15 parts of radix ophiopogonis, 4-10 parts of angelica sinensis, 4-10 parts of ground beetles, 1-10 parts of ginsenoside Rb1, 1-10 parts of ginsenoside Rg1, 1-5 parts of ginsenoside Rd, 1-5 parts of ginsenoside Re, 3-10 parts of ligusticum wallichii, 3-10 parts of cortex cinnamomi and 1-10 parts of liquorice root. The traditional Chinese medicinal composition provided by the invention has functions of activating blood circulation and removing stasis, tonifying spleen and benefiting qi, and clearing away heat and toxic materials; and in addition, the traditional Chinese medicinal composition has advantages of being simple in preparation process, good in curative effect, low in side effect, convenient to take, easy in popularization and application and the like.

Description

Technical field [0001] The present invention is a Chinese medicine technology field, and especially involves the use of a Chinese medicine combination to prepare in the treatment of drugs in myocardial infarction. Background technique [0002] Myocardial infarction is part of the myocardial necrosis caused by myocardial lasting severe ischemia. Most of them occur in the middle age. The severe and lasting properties at the occurrence of the disease are similar to the symptoms of the front chest pain, palpitations, asthma, weak pulse, reduced blood pressure, and other symptoms.EssenceThe incidence of this disease has increased year by year. Arteriosclerosis accounts for 98%of the incidence of acute myocardial infarction. Patients are mostly 40 years old, and they are mostly accompanied by hypertension. Nearly half of the history of angina pectoris. [0003] In terms of treatment, it can be roughly divided into two categories: one is to treat the standard and the root cause, that is...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8968A61P9/10A61K35/64A61K31/704
Inventor 罗奕珺
Owner 罗奕珺
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