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Medicine combination treating thyroncus and application thereof

A technology of goiter and composition, applied in the field of traditional Chinese medicine, can solve problems such as thyroid function decline, permanent scars, and ineffective effects, and achieve the effects of reducing follicular epithelial hyperplasia, increasing glial formation, and enhancing immunity

Inactive Publication Date: 2016-01-13
王亚鹤
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the treatment of this disease generally adopts surgical treatment, but the decline of thyroid function often occurs after the operation, and even permanent scars are left; clinicians often use levothyroxine to treat goiter, but the curative effect is slow and the course of treatment is long. not obvious

Method used

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  • Medicine combination treating thyroncus and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] The preparation of embodiment 1 Chinese medicine capsule

[0013] Weigh 2.9kg sweet potato vine, 1.5kg agrimony, 2.9kg cat's claw, 1.0kg chili pepper, 0.7kg single-flowered iris, 0.7kg red calla, 1.2kg eurya longan, 0.8kg Jiangnan and 0.8kg ephedra, Combine, add 10 times the amount of water of the total mass of the medicinal materials, soak for 1 hour, then decoct three times, decoct for 1.5 hours for the first time, filter out the medicinal liquid for use; add 9 times the amount of water for the second time, decoct for 1.2 hours, filter Take out the liquid medicine for use; add 8 times the amount of water for the third time, decoct for 1.0h, filter out the medicine liquid for use; combine the three decoctions, filter, and collect the filtrate; concentrate the filtrate to a thick paste, bake at low temperature for 7 hours, and pulverize , through a 100-mesh sieve to obtain dry cream powder; add dextrin according to the weight ratio of dry cream powder: dextrin of 1:5, d...

Embodiment 2

[0014] The preparation of embodiment 2 Chinese medicine capsules

[0015] Weigh 3.3kg of Sweet Potato Vine, 2.0kg of Agrimony, 2.8kg of Cat’s Claw, 1.2kg of Chili Pepper, 0.8kg of Iris uniflora, 0.8kg of Red Calla, 1.5kg of Euphorbia villosa, 0.8kg of Wangjiangnan and 0.8kg of Ephedra, Combine, add 11 times the amount of water of the total mass of medicinal materials, soak for 1 hour, then decoct three times, decoct for 1.5 hours for the first time, filter out the medicinal liquid for use; add 10 times the amount of water for the second time, decoct for 1.2 hours, filter Take out the liquid medicine for use; add 9 times the amount of water for the third time, decoct for 1.0h, filter out the medicine liquid for use; combine the three decoctions, filter, and collect the filtrate; concentrate the filtrate to a thick paste, bake at low temperature for 7 hours, and crush , through a 100-mesh sieve to obtain dry cream powder; add dextrin according to the weight ratio of dry cream po...

Embodiment 3

[0016] Example 3 Experimental Research on the Impact of Traditional Chinese Medicine on Goiter Animal Model

[0017] There were 24 healthy SD male rats with a body weight ranging from 160 to 180 g. After one week of adaptive feeding, all rats were randomly divided into the following three groups: normal group, model control group, and traditional Chinese medicine group, with 8 rats in each group. After the start of the test, taking the rat body weight as a benchmark, the Chinese medicine group was given Chinese medicine dry paste powder (prepared by the prescription process of Embodiment 1 of the present invention), and the dosage was 590 mg / kg, administered 1 time sooner or later every day; normal The model group and the model control group were given equal volumes of purified water, and the three groups were given the corresponding test substances by intragastric administration for 12 days. On the 3rd day after administration, except the normal group, the other two groups w...

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Abstract

The invention discloses medicine combination treating thyroncus and application thereof. The combination is composed of active components and pharmaceutical auxiliaries. The active components are prepared from, by weight, 25-33 parts of ficus tikoua, 11-20 parts of hairyvein agrimony, 25-33 parts of ternate buttercup roots, 7-12 parts of red cluster peppers, 4-9 parts of iris uniflora, 4-9 parts of calla palustris, 9-15 parts of eurya patentipila chun, 6-9 parts of senna occidentalis and 6-9 parts of ephedra. The medicine can inhibit hyperplasia of thyroid tissue and promote differentiation of the thyroid tissue, and therefore hard lumps can be removed, and therefore the medicine combination has the functions of inducing diuresis for removing edema and boosting immunity and can be used for treating thyroid enlargement.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a pharmaceutical composition for treating goiter and its application. Background technique [0002] Simple goiter is a goiter with normal thyroid function. It is a compensatory goiter caused by iodine deficiency, goiter substances or related enzyme defects, without obvious hyperthyroidism or hypothyroidism. Non-toxic goiter is called non-toxic goiter, which is characterized by sporadic goiter in non-endemic areas without tumors and inflammation. The thyroid gland is usually diffusely enlarged at the beginning of the course of the disease, and can develop into multinodular enlargement later. In recent years, the incidence and diagnosis rate of goiter have been increasing. When it is severe, it will oppress surrounding organs and easily cause difficulty in eating and breathing. At present, the treatment of this disease generally adopts surgical tre...

Claims

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Application Information

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IPC IPC(8): A61K36/888A61P5/14
Inventor 王亚鹤
Owner 王亚鹤
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