Application of pharmaceutical composition containing folium artemisiae argyi in preparing medicine for treating myocardial infarction

The technology of a composition and medicine is applied in the field of preparing medicines for treating myocardial infarction, and can solve the problems that the effect of replenishing qi and nourishing yin is not very significant, unfavorable to industrialized production, complicated medicine taste, etc. full effect

Inactive Publication Date: 2016-02-10
JINAN UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Chinese patent application 201410113088.8 discloses a pharmaceutical composition for the treatment of myocardial infarction. The raw materials for its preparation include: gallnut, honeysuckle, eucommia, thistle, chuanxiong, rehmannia glutinosa, cicada slough, poria cocos, white peony root, codonopsis and licorice. It has a good therapeutic effect in the treatment of myocardial infarction and has significant clinical promotion value, but

Method used

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  • Application of pharmaceutical composition containing folium artemisiae argyi in preparing medicine for treating myocardial infarction
  • Application of pharmaceutical composition containing folium artemisiae argyi in preparing medicine for treating myocardial infarction

Examples

Experimental program
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Effect test

Embodiment 1

[0037] The pharmaceutical composition involved in the present invention is prepared from the following raw materials in parts by weight: 12 parts of gastrodia elata, 13 parts of Artemisia argyi, 10 parts of Maodongqing, 8 parts of Chuanxiong, 8 parts of red peony, 6 parts of apocynum, 5 parts of white peony, 3 parts of huixincao, 5 parts of longan meat, 5 parts of yam and 7 parts of licorice.

[0038] Preparation:

[0039] A) Weigh Gastrodia elata, crush it, pass through a 100-mesh sieve, add 8 times its weight in an ethanol solution with a volume fraction of 75%, soak for 20 hours, and ultrasonically extract twice at 50°C for 2 hours each time, and the ultrasonic frequency is 30kHz, filter, combine the filtrates to obtain the Gastrodia elata extract, and keep the Gastrodia elata dregs;

[0040] B) Weigh Artemisia argyi leaves, crush them, pass through a 100-mesh sieve, add 7 times its weight in water, soak for 0.5h, heat and extract twice with water vapor, 2 hours each time,...

Embodiment 2

[0045] The pharmaceutical composition involved in the present invention is prepared from the following raw materials in parts by weight: 10 parts of Gastrodia elata, 10 parts of Artemisia argyi, 8 parts of Maodongqing, 5 parts of Rhizoma Chuanxiong, 5 parts of Radix Paeoniae Rubra, 3 parts of Apocynum apocynum, 3 parts of Radix Paeoniae Alba, 1 part of huixincao, 1 part of longan meat, 1 part of yam and 1 part of licorice.

[0046] The preparation method is similar to Example 1.

Embodiment 3

[0048] The pharmaceutical composition involved in the present invention is prepared from the following raw materials in parts by weight: 15 parts of Gastrodia elata, 15 parts of Artemisia argyi, 13 parts of Maodongqing, 10 parts of Rhizoma Chuanxiong, 10 parts of Radix Paeoniae Rubra, 8 parts of Apocynum apocynum, 8 parts of Radix Paeoniae Alba, 6 parts of huixincao, 6 parts of longan meat, 8 parts of yam and 10 parts of licorice.

[0049] Preparation:

[0050] A) Weigh Gastrodia elata, crush it, pass through a 100-mesh sieve, add 5 times its weight in an ethanol solution with a volume fraction of 65%, soak for 10 hours, and ultrasonically extract twice at 40°C for 2 hours each time, and the ultrasonic frequency is 25kHz, filter, combine the filtrates to obtain the Gastrodia elata extract, and keep the Gastrodia elata dregs;

[0051] B) Weigh Artemisia argyi leaves, crush them, pass through a 100-mesh sieve, add 7 times its weight in water, soak for 1 hour, heat and extract t...

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Abstract

The invention belongs to the field of a traditional Chinese medicine, and relates to application of a pharmaceutical composition containing folium artemisiae argyi in preparing a medicine for treating myocardial infarction. The pharmaceutical composition is prepared from the following raw materials in parts by weight: 10-15 parts of rhizoma gastrodiae, 10-15 parts of folium artemisiae argyi, 8-13 parts of radix ilicis pubescentis, 5-10 parts of ligusticum wallichii, 5-10 parts of radix paeoniae rubra, 3-8 parts of apocynum venetum, 3-8 parts of radix paeoniae alba, 1-6 parts of red rhodobryum, 1-6 parts of arillus longan, 1-8 parts of Chinese yam and 1-10 parts of liquorice root. The pharmaceutical composition disclosed by the invention has functions of promoting blood circulation to remove meridian obstruction, tranquilizing by nourishing heart, calming liver and relieving pain, nourishing spleen and tonifying qi; and in addition, the pharmaceutical composition also has advantages of being simple in preparation process, good in curative effect, low in side effects, convenient to take, easy in popularization and application, and the like.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to the use of a medicinal composition containing leaves of mugwort for preparing a medicine for treating myocardial infarction. Background technique [0002] Myocardial infarction refers to the occlusion of a coronary artery, causing necrosis of the corresponding part of the myocardium due to severe ischemia. Clinically, there are severe and persistent retrosternal pain, fever, leukocytosis, accelerated erythrocyte sedimentation rate, increased serum myocardial enzyme activity and progressive ECG changes, and arrhythmia, shock or heart failure may occur. Most patients with this disease are accompanied by or have hypertension before the onset, and nearly half of the patients have a history of angina pectoris in the past. People who smoke, are obese, have diabetes, and are physically inactive are more susceptible to the disease. [0003] The basic ca...

Claims

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Application Information

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IPC IPC(8): A61K36/8988A61P9/10
Inventor 王一飞任哲利奕成刘秋英
Owner JINAN UNIVERSITY
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