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Mucosa-repairing gel containing human-like collagen

A human-like collagen and gel technology, applied in medical science, bandages, etc., can solve the problem of not paying attention to the transdermal absorption rate of collagen, and achieve the effect of accelerating transdermal absorption, stimulating regeneration, and good nourishment

Active Publication Date: 2016-06-29
SHAANXI GIANT BIOTECHNOLOGY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Unfortunately, the studies so far have only focused on the transdermal absorption rate of collagen, but not on the transdermal absorption rate of collagen.

Method used

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  • Mucosa-repairing gel containing human-like collagen
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  • Mucosa-repairing gel containing human-like collagen

Examples

Experimental program
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Effect test

preparation example Construction

[0030] There is no special limitation on the preparation method of the human-like collagen gel of the present invention, and the usual preparation method may include:

[0031] Step A: preparing phase A, the phase A is composed of 0.03-3% by weight of carbomer, 5-20% by weight of glycerin, 0.001-0.1% by weight of sodium hyaluronate and the rest of water;

[0032] Step B: preparing phase B, the phase B is human-like collagen liquid, which contains human-like collagen such that the content of human-like collagen in the human-like collagen gel is 0.01-1% by weight, medium It is water, and the weight ratio of the human-like collagen to the water is 1:1-20;

[0033] Step C: preparing phase C, the phase C is 0.01-1% by weight of polysorbate 80; and

[0034] Step D: Add the phase B into the phase A, heat to 80-85°C, keep it warm for 20-60 minutes, then cool down to 50-60°C, add the phase C, stir evenly, and cool to room temperature;

[0035] The total weight of the human-like colla...

Embodiment 1

[0046] Embodiment 1. Preparation of human-like collagen gel of the present invention

[0047] Ingredients: Carbomer 0.3%, Glycerin 10%, Sodium Hyaluronate 0.01%, Human Collagen 0.5%, Polysorbate 800.1%, Water 89.09%.

[0048] Process operation:

[0049] ①Add carbomer and sodium hyaluronate to water first, then slowly add glycerin and stir continuously until they are completely dispersed. Then add human-like collagen aqueous solution (10% by weight), stir while adding until completely dissolved, heat to 80-85° C., and keep warm for 30 minutes;

[0050] ②Reduce the temperature of the above mixture to 50-60°C, add polysorbate 80, stir evenly, and cool to room temperature.

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Abstract

The invention relates to the field of medical / cosmetic apparatuses, and in particular relates to mucosa-repairing gel containing human-like collagen, wherein the rapid transdermal absorption of the human-like collagen can be promoted. The mucosa-repairing gel containing human-like collagen can be used for repairing the mucosa in the medical / cosmetic field. The mucosa-repairing gel contains the human-like collagen, Carbomer, glycerol, sodium hyaluronate, polysorbate-80 and water.

Description

technical field [0001] The invention relates to a dressing of human-like collagen, in particular to a gel for repairing mucous membranes containing human-like collagen, and belongs to the field of cosmetic / medical equipment. Background technique [0002] Human-like collagen was invented by Professor Fan Daidi of Northwest University in China (see Chinese Patent Application Publication CN1371919A), so it is also called Fan's Human-like Collagen or Fan's Human-like Collagen (FHLC). Human-like collagen has a three-chain, triple-helix structure, and is a highly biocompatible recombinant collagen, which is currently widely used in medical or cosmetic fields. [0003] On the other hand, when collagen dressings are used to moisten and protect the mucous membranes of the nasal cavity, anorectum, and gynecology, the use of collagen dressings often needs to be done indoors (such as the otolaryngology, anorectal, and gynecology departments of hospitals, etc.) , as a product user hopes...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L26/00
CPCA61L26/0014A61L26/0023A61L26/0033A61L26/0066A61L26/008A61L2300/252A61L2300/412C08L5/08C08L33/02
Inventor 范代娣马晓轩严建亚王淑英常海燕王小军杨婵媛
Owner SHAANXI GIANT BIOTECHNOLOGY CO LTD
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