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Antidote for preventing and treating aflatoxin poisoning in poultry and livestock

A kind of technology of aflatoxin and antidote, which is applied in the direction of antidote, animal husbandry, additional food elements, etc., can solve the problems of body weight gain and the decline of feed protein utilization rate, and achieve the relief of poultry poisoning symptoms, reasonable compatibility, no Toxic effects

Active Publication Date: 2019-02-05
ZHEJIANG AEGIS BIOLOGICAL SCI & TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

28-day-old Arabian ducks fed 50 μg / kg AFB 1 body weight gain and dietary protein utilization decreased significantly after
[0031] At present, the combination of glutathione and berberine for the prevention and treatment of aflatoxin poisoning has not been reported

Method used

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  • Antidote for preventing and treating aflatoxin poisoning in poultry and livestock

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] Embodiment 1, the preparation of the antidote containing reduced glutathione

[0048] Get 50 parts by weight of bone meal and 5 parts by weight of reduced glutathione, mix them to make antidote A1.

Embodiment 2

[0049] Embodiment 2, the preparation of the antidote containing berberine

[0050] Get 50 parts by weight of bone powder and 5 parts by weight of berberine, and mix them to make antidote A2.

Embodiment 3

[0051] Embodiment 3, the preparation of the antidote comprising reduced glutathione and berberine (1:9)

[0052] Take 50 parts by weight of bone powder, 0.5 parts by weight of reduced glutathione, and 4.5 parts by weight of berberine, and mix them to make antidote A3 with a weight ratio of reduced glutathione and berberine of 1:9.

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Abstract

The invention relates to an antidote for preventing and treating livestock aflatoxicosis. The weight ratio of active ingredients, namely, glutathione and berberine, is (1:20)-(20:1). Compared with a common antidote, the livestock feed antidote provided by the invention is simple to prepare and reasonable in compatibility and can remarkably relieve the toxic symptoms of the livestock and is proved by experiments to have a special effect on preventing and treating livestock aflatoxicosis; and without Western medicine components in additives, the antidote avoids toxic and side effects, drug resistance and pollution.

Description

technical field [0001] The invention relates to the field of feed, in particular to a livestock feed additive and its application. Background technique [0002] Aflatoxin (AF) is a metabolite of Aspergillus flavus and Aspergillus parasiticus, they are a kind of derivatives of dihydrofuran anaphthalene with similar structure and physical and chemical properties, and they are the most stable physical and chemical properties found in nature. Mycotoxins. At present, 12 species have been isolated and identified, including: B 1 , B 2 , G 1 , G 2 , M 1 , M 2 ,P 1 , Q, H 1 , B 2a , G 2a and toxic alcohol. The toxicity of aflatoxins is very strong, among which B 1 Most toxic, M 1 , G 1 next, and B 2 , G 2 and M 2 weaker. B 1 The toxicity of potassium cyanide is 10 times that of potassium cyanide and 68 times that of arsenic. [0003] Because aflatoxin contains a macrocyclic conjugated system, it has very good stability and its decomposition temperature is as high ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K38/06A61P39/02A23K20/147A23K20/132A61K31/4375
CPCA61K31/4375A61K38/06A61K2300/00Y02A40/70
Inventor 潘宏涛卢亚萍
Owner ZHEJIANG AEGIS BIOLOGICAL SCI & TECH CO LTD
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