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Medicinal preparation for treating early threatened abortion complicated with SCH (sub-chorionic hematoma)

A pharmaceutical preparation and threatened abortion technology, applied in the field of pharmaceutical preparations and preparations for the treatment of early threatened abortion combined with subchorionic hematoma, can solve the problems of increasing the difficulty of miscarriage

Inactive Publication Date: 2016-07-27
王剑
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Studies have shown that SCH with less than 25% gestational sac area has a better prognosis, while SCH with more than 25% gestational sac area will increase the incidence of spontaneous abortion to 49%. Therefore, threatened abortion combined with SCH is more dangerous than simple threatened abortion , increasing the difficulty of tire protection

Method used

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  • Medicinal preparation for treating early threatened abortion complicated with SCH (sub-chorionic hematoma)
  • Medicinal preparation for treating early threatened abortion complicated with SCH (sub-chorionic hematoma)
  • Medicinal preparation for treating early threatened abortion complicated with SCH (sub-chorionic hematoma)

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Embodiment 1 capsule

[0030] Prescription: 25 servings of Diluguo, 35 servings of Shuangshen, 18 servings of Geshanxiao, 15 servings of Sangjisheng, 10 servings of Akebia jinsi, 15 servings of Hengjingxi, 12 servings of Egg Bulao, and 5 servings of Schisandra chinensis.

[0031]Preparation method: According to the prescription, take Dixie fruit, Shuangshen, Geshanxiao, Sangjisheng, Jinsi Akebia, Hengjingxi, Egg Bulao, Schisandra, add 7 times the amount of water, decoct and extract twice, 1.5 hours each time, Combine the filtrates, filter, concentrate to a relative density of 1.12 (measured at 60°C), place it at room temperature, add ethanol to make the alcohol content reach 30%, stir well, place in -5-0°C for 12 hours, filter, and the filtrate reduces After recovering the ethanol by pressure until there is no alcohol smell, concentrate to dryness, pulverize into fine powder, and make capsules according to the conventional technology of pharmacy, each capsule is 0.3g, w...

Embodiment 2

[0032] Embodiment 2 capsules

[0033] Prescription: 20 servings of Diluguo, 32 servings of Shuangshen, 15 servings of Geshanxiao, 13 servings of Sangjisheng, 8 servings of Akebia chinensis, 12 servings of Hengjingxi, 10 servings of Danbulao, and 5 servings of Schisandra chinensis.

[0034] Preparation method: According to the prescription, take Dixie fruit, Shuangshen, Geshanxiao, Sangjisheng, Jinsi Akebia, Hengjingxi, Danbulao, Schisandra, add 4 times the amount of water, decoct and extract 3 times, 1.5 hours each time, Combine the filtrates, filter, concentrate to a relative density of 1.10 (measured at 60°C), place at room temperature, add ethanol to make the alcohol content reach 30%, stir well, place in -5-0°C for 12 hours, filter, and the filtrate reduces After the ethanol is recovered by pressure until it has no alcohol smell, it is concentrated to dryness, crushed into fine powder, and made into capsules according to the conventional technology of pharmacy.

Embodiment 3

[0035] Embodiment 3 capsules

[0036] Prescription: 22 servings of Diluguo, 33 servings of Shuangshen, 15 servings of Geshanxiao, 15 servings of Sangjisheng, 8 servings of Akebia chinensis, 17 servings of Hengjingxi, 10 servings of Danbulao, and 4 servings of Schisandra chinensis.

[0037] Preparation method: According to the prescription, take Dixie fruit, Shuangshen, Geshanxiao, Sangjisheng, Jinsi Akebia, Hengjingxi, Egg Bulao, Schisandra, add 8 times the amount of water, decoct and extract twice, 2 hours each time, Combine the filtrates, filter, concentrate to a relative density of 1.15 (measured at 60°C), place it at room temperature, add ethanol to make the alcohol content reach 30%, stir well, place it at -5-0°C for 12 hours, filter, and the filtrate reduces After the ethanol is recovered by pressing until it has no alcohol smell, it is concentrated to dryness and crushed into fine powder; it is made into capsules according to the conventional technology of pharmacy.

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Abstract

The invention belongs to the field of traditional Chinese medicine, and relates to a medicinal preparation for treating early threatened abortion complicated with SCH (sub-chorionic hematoma) and a preparation method of the medicinal preparation. The medicinal preparation is prepared from the medicinal materials in parts by weight as follows: melastoma dodecandrum fruits, large-flowered triplostegia tubers, auriculate cynanchum tubers, Chinese taxillus herbs, all-grass of loureiro clematis, beauty-leaf roots, cantonese speranskia and Chinese magnoliavine fruits. The medicinal materials selected by the medicinal preparation are compatible appropriately, components are refined, and disease curing and miscarriage prevention are realized simultaneously; the medicinal preparation has the effects of tonifying the kidney, activating the blood circulation, dispersing blood stasis and preventing miscarriage, and has the functions of tonifying the spleen, nourishing blood, removing dampness and dredging collaterals; the medicine property is mild, qi and blood are not injured, and medication is stopped as soon as effects are achieved, so that the medicinal preparation is beneficial to the fetus and the pregnant woman, the purpose of curing the disease without disturbing the fetus is achieved, and particularly, the medicinal preparation is developed for the patients with the kidney deficiency and blood stasis type early threatened abortion complicated with SCH on the basis of traditional Chinese medicine differentiation, and the effect is remarkable.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and relates to a pharmaceutical preparation for treating early threatened abortion combined with subchorionic hematoma and a preparation method thereof. Background technique [0002] Early threatened miscarriage refers to the occurrence of a small amount of vaginal bleeding before 12 weeks of pregnancy, accompanied by clinical manifestations such as abdominal pain and waist and knee pain. In recent years, with the influence of many factors such as rapid social development, environmental pollution, life and work pressure, and irregular work and rest, the incidence of threatened abortion has increased year by year. It is reported abroad that about 18% of early threatened abortion cases are caused by subchorionic hematoma (Sub-chorionichaematoma, SCH). Studies have shown that SCH with less than 25% gestational sac area has a better prognosis, while SCH with more than 25% gestational sac ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/716A61K36/79A61P15/06A61P7/04
CPCA61K36/27A61K36/185A61K36/47A61K36/57A61K36/716A61K36/79A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 王键
Owner 王剑
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