Unlock instant, AI-driven research and patent intelligence for your innovation.

Pharmaceutical composition containing clobopride malate and application thereof

A technology of clobopride and its composition, which is applied in the direction of drug combinations, medical preparations containing active ingredients, and pharmaceutical formulas, which can solve problems such as large side effects and poor therapeutic effects, reduce the risk of bleeding, and improve drug safety sexual effect

Inactive Publication Date: 2018-11-06
高雯聪
View PDF2 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In order to overcome the technical deficiencies of relatively large side effects and poor therapeutic effect of the existing drugs for treating gastric ulcer, the present invention provides a pharmaceutical composition for treating gastric ulcer, which is composed of clobopride malate and agaricin

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Pharmaceutical composition containing clobopride malate and application thereof
  • Pharmaceutical composition containing clobopride malate and application thereof
  • Pharmaceutical composition containing clobopride malate and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] The preparation of embodiment 1 compound tablet

[0019]

[0020] Preparation process: mix draconidin and clobopride malate with auxiliary materials microcrystalline cellulose and starch evenly, add appropriate amount of 15% starch slurry to make soft material, and pass through a 16-mesh sieve to granulate. Dry the wet granules at 60°C, pass the dry granules through a 16-mesh sieve for granulation, sieve out the fine powder in the dry granules, mix with magnesium stearate, and then mix with the dry granules, and press into tablets to obtain the product.

Embodiment 2

[0021] The preparation of embodiment 2 compound tablet

[0022]

[0023] Preparation process: except that the components are different, the preparation process is the same as that described in Example 1.

Embodiment 3

[0024] The preparation of embodiment 3 compound dispersible tablets

[0025]

[0026] Preparation process: Weigh draconidin and clobopride malate according to the prescription, use microcrystalline cellulose as filler, croscarmellose sodium and polyvinylpyrrolidone as disintegrants, 5% PVP 60 The % ethanol solution is used as a binder, the micropowdered silica gel is used as a flow aid, and it is granulated by a fluidized bed in one step, and then compressed into tablets.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a medicine composition containing malic acid clebopride malate and application thereof and belongs to the technical field of medicine. To overcome the technical defects that existing medicine for treating gastric ulcer is large in side effect and poor in treatment effect, the medicine composition containing malic acid clebopride malate is provided and is composed of malic acid clebopride malate and Qinlongkusu. The two medicine active components have a remarkable synergistic effect of treating and restraining gastric ulcer, and have a good treatment effect on gastric ulcer.

Description

technical field [0001] The invention relates to a pharmaceutical composition containing clobopride malate and an application thereof, belonging to the technical field of medicine. Background technique [0002] Peptic ulcer (PU) mainly refers to chronic ulcers that occur in the stomach and duodenum, that is, gastric ulcer and duodenal ulcer, and can also occur in the lower end of the esophagus, near the gastroduodenal anastomosis and Meckel's diverticulum. Western medicine classifies it as a localized tissue defect that can involve the mucosa, submucosa, and muscle layer. Traditional Chinese medicine classifies it as "epigastric pain" based on its clinical symptoms. The disease has a long course of disease, repeated attacks, and complex clinical manifestations. It is a common chronic gastrointestinal disease worldwide. It is reported that peptic ulcer accounts for 10.3% to 2.6% of the domestic gastroscopy population. The disease can be seen at any age, mostly between 20 an...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/7048A61K31/4468A61P1/04
CPCA61K31/4468A61K31/7048A61K2300/00
Inventor 高雯聪王永林王晓岳
Owner 高雯聪
Features
  • R&D
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com