Microneedle drug delivery patch containing separable drug capsule

Abstract

The invention discloses a flexible microneedle drug delivery patch containing a separable drug capsule suitable for transdermal delivery of multiple drugs. The microneedle drug delivery patch has the advantages that pain level is low, infection risk is low and application is convenient. The microneedle drug delivery patch comprises the separable and replaceable drug capsule, a drug carrying end integrating a microneedle array with a microfluid flow passage network, a drug delivering end integrating the microneedle array with the microfluid flow passage network, and a sticky patch body allowing the microneedle drug delivery patch to be attached to skin, wherein the sticky patch body is made from a flexible polymer and is high in curvature and skin bonding property. In use, the drug delivery patch is attached to a joint of a user, the drug carrying end and the drug capsule of the drug delivery patch deform under the squeezing and stretching actions of the bent joint on the flexible microneedle drug delivery patch, so that a syringe needle at the drug carrying end pierces into the drug capsule and drugs are distributed to the drug delivering end through the microfluid flow passage network, and then drugs flow into the body through a passage formed on skin by a microneedle at the drug delivering end to finish drug delivery.

Description

technical field [0001] The invention relates to a transdermal drug transfusion device, in particular to a microneedle drug delivery patch containing a separate drug storage bag. Background technique [0002] Drug therapy is a common medical method, and the main delivery methods of drugs into the human body include injection and oral administration, both of which have certain limitations. During oral administration, the drug may be inactivated due to self-metabolism and lose its efficacy; subcutaneous injection requires trained personnel to implement, and brings unavoidable pain and infection risk to patients, which brings inconvenience to patients. In recent years, microneedle drug delivery has attracted more and more attention. Microneedles are micron-sized hollow or solid needles similar to injection needles, generally made of single crystal silicon materials, metals or high molecular polymers. It can just pass through the stratum corneum without touching the pain nerve,...

AI Technical Summary

Problems solved by technology

However, after the microneedle is removed, the skin returns to normal state and the barrier function of the stratum corneum is restored, which will prevent the drug from continuing to penetrate the skin, so the effective drug delivery that can be achieved by the non-drug-loaded solid microneedle is very limited

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