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Drug compound for treating suppurative otitis media of children and preparation method thereof

A technology for suppurative otitis media and a composition is applied in the directions of drug combination, pharmaceutical formula, medical preparation containing active ingredients, etc., and can solve the problems of increasing toxicity, reducing the tension of isolated rabbit intestine, and unable to eliminate spasm and the like

Inactive Publication Date: 2016-10-26
JINAN XINGYI MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Both can reduce the tension of the isolated rabbit intestine, and have a relaxing effect on the increased intestinal tension caused by barium chloride, but cannot eliminate the spasm caused by acetylcholine
For example, the compatibility of licorice with tangerine peel and woody fragrance will increase its toxicity

Method used

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  • Drug compound for treating suppurative otitis media of children and preparation method thereof

Examples

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Comparison scheme
Effect test

Embodiment 1

[0033] Embodiment 1: The pharmaceutical composition for treating suppurative otitis media in children and its preparation method

[0034] The composition and parts by weight of the raw material drug of the pharmaceutical composition for treating suppurative otitis media in children are: 4600g of single wood, 3900g of stinky plum skin, 1100g of large duckweed, 3500g of jay jay, 1000g of dung beetle, 50g of glutamic acid, aromatic syrinthin 70g;

[0035] Preparation:

[0036] (1) According to the ratio of raw materials, take single wood, stinky plum skin, big duckweed, crow, dung beetle, glutamic acid, and aromatic melanin, mix them evenly, and use ethanol with a concentration of 31% by weight as a solvent, at 48.5 ℃ warm immersion extraction, the number of extractions is 7 times, each extraction time is 33 hours, and the amount of solvent used each time is 30 times the total weight of the crude drug, and filtered to obtain medicinal residue A and extract A, and the extract A r...

Embodiment 2

[0039] Embodiment 2: the pharmaceutical composition for treating suppurative otitis media in children and its preparation method

[0040] The composition and parts by weight of the raw materials of the pharmaceutical composition for treating suppurative otitis media in children are: 4550g of single wood, 3950g of stinky plum skin, 1050g of duckweed, 3550g of jay jay, 950g of dung beetle, 55g of glutamic acid, and aromatic chrysanthemum 65g;

[0041] Preparation:

[0042] (1) According to the ratio of raw materials, take single wood, stinky plum skin, big duckweed, crow, dung beetle, glutamic acid, and aromatic melanin, mix them evenly, and use ethanol with a concentration of 31% by weight as a solvent, at 48.5 ℃ warm immersion extraction, the number of extractions is 7 times, each extraction time is 33 hours, and the amount of solvent used each time is 30 times the total weight of the crude drug, and filtered to obtain medicinal residue A and extract A, and the extract A recl...

Embodiment 3

[0045] Embodiment 3: the pharmaceutical composition for treating suppurative otitis media in children and its preparation method

[0046] The composition and parts by weight of the raw material drug of the pharmaceutical composition for treating children's suppurative otitis media are: 4650g of single wood, 3850g of stinky plum skin, 1150g of duckweed, 3450g of jay jay, 1050g of dung beetle, 45g of glutamic acid, aromatic syrinthin 75g;

[0047] Preparation:

[0048] (1) According to the ratio of raw materials, take single wood, stinky plum skin, big duckweed, crow, dung beetle, glutamic acid, and aromatic melanin, mix them evenly, and use ethanol with a concentration of 31% by weight as a solvent, at 48.5 ℃ warm immersion extraction, the number of extractions is 7 times, each extraction time is 33 hours, and the amount of solvent used each time is 30 times the total weight of the crude drug, and filtered to obtain medicinal residue A and extract A, and the extract A reclaims...

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Abstract

The invention discloses a drug compound for treating suppurative otitis media of children and a preparation method thereof. The drug compound disclosed by the invention is prepared from hainan ervatamia root, rhamnus davurica pall, duckweed, Japanese aralia bark, dung beetle, glutamic acid and odoratin as raw materials. The drug compound can be prepared into various preparations according to the conventional preparation technique and has an obvious effect on treating suppurative otitis media of children.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a pharmaceutical composition for treating suppurative otitis media in children and a preparation method thereof. Background technique [0002] Suppurative otitis media in children is a suppurative inflammation of the middle ear mucosa, which occurs frequently in children and is also a common cause of hearing loss in children. Acute suppurative otitis media is a common infectious disease in childhood, with a high incidence rate, easy recurrence, and many complications and sequelae. Serious complications include intracranial complications, such as meningitis, brain abscess, etc. Other complications include labyrinthitis, facial paralysis, etc. Therefore, suppurative otitis media in children should arouse the attention of parents and society. [0003] The current drugs for treating suppurative otitis media in children mainly include: antibiotic aq...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/888A61P27/16A61K35/64A61K31/198A61K31/365
CPCA61K36/888A61K31/198A61K31/365A61K35/63A61K36/24A61K36/25A61K36/72A61K2236/55A61K2236/51A61K2236/39A61K2236/333A61K2300/00
Inventor 不公告发明人
Owner JINAN XINGYI MEDICAL TECH
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