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Application of phillyrin, phillyrin derivatives, and phillyrin-phillygenin composition in preparation of drugs or health care products for relief or/and treatment of vomiting

A technology of forsythin derivatives and forsythiatin, which is applied in the field of medicine, can solve the problems of delayed vomiting and poor curative effect, and achieve the effects of strong pharmacological effects, good medicinal prospects, and good safety

Active Publication Date: 2016-11-02
富力
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It has a wide range of tolerance, few side effects, and has obvious curative effect on acute vomiting, but some studies have found that 5-HT 3 Receptor antagonists are less effective in delayed emesis

Method used

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  • Application of phillyrin, phillyrin derivatives, and phillyrin-phillygenin composition in preparation of drugs or health care products for relief or/and treatment of vomiting
  • Application of phillyrin, phillyrin derivatives, and phillyrin-phillygenin composition in preparation of drugs or health care products for relief or/and treatment of vomiting
  • Application of phillyrin, phillyrin derivatives, and phillyrin-phillygenin composition in preparation of drugs or health care products for relief or/and treatment of vomiting

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] Example 1 Forsythin tablets

[0045] 1. Prepare the raw materials according to the following ratio

[0046]

[0047] 2. After mixing forsythin and starch uniformly, make granules, add talc and magnesium stearate and mix them evenly, then press to make 10,000 tablets.

Embodiment 2

[0048] Example 2 Forsythin capsules

[0049] 1. Prepare the raw materials according to the following ratio

[0050] Forsythin (purity 60%) 200g

[0051] Starch 1000g

[0052] 2. Mix forsythin and starch uniformly and then encapsulate them to make 10,000 capsules.

Embodiment 3

[0053] Example 3 Forsythin capsules

[0054] 1. Prepare the raw materials according to the following ratio

[0055] Forsythin (98% purity) 500g

[0056] Starch 1000g

[0057] 2. Mix forsythin and starch uniformly and then encapsulate them to make 10,000 capsules.

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PUM

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Abstract

The invention discloses new application of phillyrin, phillyrin derivatives, and a phillyrin-phillygenin composition in preparation of drugs or health care products for relief or / and treatment of vomiting. Tests prove that the phillyrin, phillyrin derivatives, and phillyrin-phillygenin composition have the characteristics of significant vomiting relief or treatment effect, quick effect and small toxic and side effect, are a safe, efficient and stable vomiting treatment drug with a simple preparation process, and are suitable for industrial production and easy for popularization. The invention provides a new drug source for prevention and treatment of vomiting and its complications.

Description

Technical field [0001] The invention relates to the field of medicine, and relates to a medicine or health food for treating vomiting, in particular to the application of a Chinese medicine forsythia and forsythia leaf extracts in medicines or health foods for relieving or / and treating vomiting. Background technique [0002] Vomiting is a defensive reaction involving the peripheral and central nervous systems. It is caused by the strong co-contraction of the diaphragm and abdominal muscles, which causes the stomach substances to be reflexively discharged from the body through the esophagus and oral cavity. Vomiting can remove harmful substances in the stomach. discharge. Many factors can cause nausea and vomiting, such as labyrinth irritation, pain in internal organs after surgery, pregnancy, vestibular irritation, etc. Chemotherapy and radiotherapy, an important treatment for cancer at present, cause intense nausea and vomiting, which not only affects the appetite and digestion...

Claims

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Application Information

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IPC IPC(8): A61K31/7048A61K36/9064A61K36/9062A61K36/754A61K36/899A61K36/8888A61K36/532A61K36/835A61K36/28A61K36/535A61K36/61A61K36/73A23L33/00A61P1/08A61K31/34A61K31/375
Inventor 王凯乾富力惠敏鲁明明王硕樊宏宇柳洋盖鑫周庆丰
Owner 富力
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