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Dental ulcer spray and preparation method thereof

An oral ulcer and spray technology, which is applied in the field of oral ulcer spray and its preparation, can solve the problems such as inability to achieve wound surface isolation, no pain relief function, prolonged treatment period, etc., so as to facilitate ulcer healing, prevent ulcer infection, avoid ulcer The effect of cross infection

Inactive Publication Date: 2016-11-16
怡越医疗(广东)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, these methods, on the one hand, have poor treatment effect and long treatment time; on the other hand, they do not have the function of pain relief, and the patient’s brushing teeth touches the ulcer is also very uncomfortable; on the other hand, it is impossible to achieve wound isolation, and external pollutants may Cause secondary infection on the wound surface, further prolonging the treatment cycle

Method used

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  • Dental ulcer spray and preparation method thereof
  • Dental ulcer spray and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Oral ulcer spray, in parts by mass, consists of 1-3 parts of regenerative agent, 0.3-0.5 part of anti-inflammatory agent, 1-4 parts of film-forming agent, 0.5-2.5 parts of porogen, and 0.1-0.2 part of suspending agent 0.1-0.2 parts of antioxidant, 0.1-0.2 parts of astringent and 92-98 parts of solvent.

[0024] In the present embodiment, described regenerative agent is alanyl glutamine; Anti-inflammatory agent is the mixture of nano-silver, nano-zinc and chitosan, and wherein, the weight ratio of nano-silver, nano-zinc and chitosan is 1: 2:0.5; the film-forming agent is polyvinyl butyral; the porogen is a mixture of polyvinylpyrrolidone and glycerin, wherein the mass ratio of polyvinylpyrrolidone and glycerin is 1:1.26; the suspending agent is sodium alginate; the antioxidant is water-soluble coenzyme Q10; the astringent is calamine; the solvent is ethanol.

[0025] In this embodiment, the model of the polyvinyl butyral has a viscosity of 250CPS-280CPS or 10s-15s; the ...

Embodiment 2

[0033] Oral ulcer spray, in parts by mass, consists of 1-3 parts of regenerative agent, 0.3-0.5 part of anti-inflammatory agent, 1-4 parts of film-forming agent, 0.5-2.5 parts of porogen, and 0.1-0.2 part of suspending agent 0.1-0.2 parts of antioxidant, 0.1-0.2 parts of astringent and 92-98 parts of solvent.

[0034]In the present embodiment, described regenerative agent is alanyl glutamine; Anti-inflammatory agent is the mixture of nano-silver, nano-zinc and chitosan, and wherein, the weight ratio of nano-silver, nano-zinc and chitosan is 1: 2:0.5; the film-forming agent is polyvinyl butyral; the porogen is a mixture of polyvinylpyrrolidone and glycerin, wherein the mass ratio of polyvinylpyrrolidone and glycerin is 1:1.26; the suspending agent is sodium alginate; the antioxidant is water-soluble coenzyme Q10; the astringent is calamine; the solvent is ethanol.

[0035] In this embodiment, the model of the polyvinyl butyral has a viscosity of 250CPS-280CPS or 10s-15s; the s...

Embodiment 3

[0043] Oral ulcer spray, in parts by mass, consists of 1-3 parts of regenerative agent, 0.3-0.5 part of anti-inflammatory agent, 1-4 parts of film-forming agent, 0.5-2.5 parts of porogen, and 0.1-0.2 part of suspending agent 0.1-0.2 parts of antioxidant, 0.1-0.2 parts of astringent and 92-98 parts of solvent.

[0044] In the present embodiment, described regenerative agent is alanyl glutamine; Anti-inflammatory agent is the mixture of nano-silver, nano-zinc and chitosan, and wherein, the weight ratio of nano-silver, nano-zinc and chitosan is 1: 2:0.5; the film-forming agent is polyvinyl butyral; the porogen is a mixture of polyvinylpyrrolidone and glycerin, wherein the mass ratio of polyvinylpyrrolidone and glycerin is 1:1.26; the suspending agent is sodium alginate; the antioxidant is water-soluble coenzyme Q10; the astringent is calamine; the solvent is ethanol.

[0045] In this embodiment, the model of the polyvinyl butyral has a viscosity of 250CPS-280CPS or 10s-15s; the ...

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Abstract

The invention relates to the field of dental ulcer treatment medicine, in particular to a dental ulcer spray and a preparation method thereof. The dental ulcer spray is prepared from, by mass, 1-3 parts of regeneration promoter, 0.3-0.5 part of anti-inflammatory agent, 1-4 parts of film-forming agent, 0.5-2.5 parts of pore-foaming agent, 0.1-0.2 part of suspending agent, 0.1-0.2 part of antioxidant, 0.1-0.2 part of astringent and 92-98 parts of solvent. The dental ulcer spray is good in treatment effect, and meanwhile has the effects of diminishing inflammation, relieving pain and promoting ulcer healing.

Description

technical field [0001] The invention relates to the field of drugs for treating oral ulcers, in particular to a spray for oral ulcers and a preparation method thereof. Background technique [0002] Oral ulcer is a common ulcerative injury disease that occurs in the oral mucosa. It is more common in the inner lip, tongue, tongue abdomen, buccal mucosa, vestibular groove, soft palate and other parts. The mucosa in these parts lacks cornified layer or poor keratinization . Tongue ulcers refer to oral ulcers that occur on the tongue and the abdomen of the tongue. When oral ulcers attack, the pain is severe, and the local burning pain is obvious. In severe cases, it will also affect eating and speaking, causing great inconvenience to daily life; Symptoms such as swollen lymph nodes. [0003] For the treatment of oral ulcers, it is mainly to eliminate the cause of the disease, strengthen the body, and treat symptoms. The treatment method should adhere to the combination of syst...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/05A61K9/12A61K47/36A61K47/10A61P1/02A61P29/00A61P31/02A61P7/04A61K33/30A61K31/722A61K31/047A61K33/38A61K31/122A61K31/765A61K31/79
CPCA61K33/38A61K9/006A61K9/12A61K31/047A61K31/122A61K31/722A61K31/765A61K31/79A61K33/30A61K38/05A61K47/10A61K47/36A61K2300/00
Inventor 万元江
Owner 怡越医疗(广东)有限公司
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