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Application of gynecological great herbal medicine composition and antibiotic in preparation of drug for treating thymus diseases

A technology of gynecological daughter and composition, which is applied in the field of medicine and can solve problems such as unseen technical reports

Inactive Publication Date: 2016-11-23
ZHUZHOU QIANJIN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] At present, there is no relevant technical report on the combination of traditional Chinese medicine composition and azithromycin in the preparation of drugs for the treatment of thymus diseases

Method used

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  • Application of gynecological great herbal medicine composition and antibiotic in preparation of drug for treating thymus diseases
  • Application of gynecological great herbal medicine composition and antibiotic in preparation of drug for treating thymus diseases
  • Application of gynecological great herbal medicine composition and antibiotic in preparation of drug for treating thymus diseases

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] 1. Experimental strains: Staphylococcus aureus (ATCC25923), Escherichia coli (ATCC25922) were purchased from China National Culture Bank. Suspend the lyophilized powder of the tested strains in sterile M-H(B) medium and spread evenly on the surface of the sterile M-H(A) plate, incubate overnight at 35°C for revival, after 18 hours a lawn grows on the surface of the plate, select the ones with good growth Single bacterial mass, re-smear on the M-H(A) slant, incubate under the same conditions for 18h, seal, and store in refrigerator at 4°C; the day before the test, take the slant bacteria and smear it on the M-H(A) plate, incubate overnight at 35°C, ready to use . All operations are done on a clean bench.

[0021] 2. Bacteria solution preparation method

[0022] Method 1: (preparation of high-concentration bacterial solution)

[0023] Pick 3-4 single colonies in 40 ml of M-H(B) medium. The test bacteria were enriched and cultured overnight for 16 hours (37°C, shaken i...

Embodiment 2

[0056] Example 2 The test of Chinese medicine composition of the present invention combined with azithromycin in adjuvant treatment of thymus-related diseases

[0057] Myasthenia gravis (MG) is an acquired autoimmune disease of neuromuscular junction transmission dysfunction. Its exact pathogenesis is still unclear, but there are many studies on the disease, among which the most studied is the relationship between myasthenia gravis and the thymus. Studies have shown that the increase of anti-Achr antibodies in the serum and the reduction of the number of effective Acr caused by the deposition on the postsynaptic membrane are the main reasons for the occurrence of this disease. The thymus is the main place where Achr antibody is produced. Therefore, the occurrence of this disease is generally closely related to the thymus. This example is based on the previous study on the effect on the thymus viscera index, aiming to understand the role of the traditional Chinese medicine com...

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Abstract

The invention discloses the application of Fuke Qianjin Fang composition combined with antibiotics in the preparation of medicines for treating thymus diseases, especially the application in the preparation of medicines for improving thymus hyperemia, edema and hyperplasia. The antibiotic is azithromycin. The active ingredients of the gynecological Qianjin prescription composition are composed of Qianjinba, Andrographis paniculata, Rosa root, Gongluomu, Shuangmianzhen, Caulis Spatholobus, Angelica and Codonopsis pilosula. The traditional Chinese medicine composition of the present invention combined with azithromycin has a good application effect in improving thymus hyperemia, edema, hyperplasia and the like.

Description

technical field [0001] The invention relates to the technical field of medicine, and more specifically, relates to the application of a combination of Fuke Qianjin Fang composition combined with antibiotics in the preparation of medicines for treating thymus diseases. technical background [0002] Thymus (thymus) The thymus is located in the prethoracic mediastinum and is an important lymphatic organ of the body. Its function is closely related to immunity. It is the place where T cells differentiate, develop and mature. It can also secrete thymus hormones and hormone substances. It is an organ with endocrine function. The thymus is known as the "life clock" of human beings, and recent studies have shown that it is closely related to the length of human life. [0003] The thymus is an important organ of human immunity, especially cellular immunity. Therefore, when the thymus is diseased, it will have a serious impact on the immune function of the body, causing the body's im...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/758A61P37/02A61P5/00A61K31/7052
CPCA61K36/48A61K31/7052A61K36/19A61K36/232A61K36/29A61K36/344A61K36/486A61K36/738A61K36/758A61K2300/00
Inventor 李伏君龚云李维刘逆夫张鹏
Owner ZHUZHOU QIANJIN PHARMA
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