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Application of traditional Chinese medicine composition to preparation of medicine for treating chronic gout

A technology for chronic gout and composition, applied in the field of traditional Chinese medicine, can solve the problems of few traditional Chinese medicines, few varieties of Chinese patent medicines for gout, etc., and achieve the effect of less toxic and side effects

Inactive Publication Date: 2016-11-23
HEILONGJIANG UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] However, currently there are few types of Chinese patent medicines for the treatment of gout, most of the few Chinese patent medicines are for the treatment of acute gouty arthritis, and there are only a handful of Chinese medicines for the treatment of chronic gout

Method used

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  • Application of traditional Chinese medicine composition to preparation of medicine for treating chronic gout
  • Application of traditional Chinese medicine composition to preparation of medicine for treating chronic gout

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] (1) According to 18 parts of Polygonum cuspidatum, 16 parts of Plantaginaceae, 12 parts of Caulis Caulis, 12 parts of Cervus pilaster, 11 parts of turmeric, 9 parts of Caulis Spatholobus, 8 parts of Chinese yam, and 9 parts of Cuscuta chinensis, weigh the Chinese herbal medicines, cleanly select, Crushed into coarse powder, set aside;

[0023] (2) Add 10 times the amount of water to the coarse powder obtained in step (1), heat it to boiling, decoct on low heat for 3.5 hours, filter to obtain the filtrate, add 8 times the amount of water to the filter residue and decoct twice, 3 hours each time, filter , combine the filtrates, concentrate to a thick paste, place in a vacuum drying oven, and dry at 65°C to obtain a dry extract, crush the dry extract into fine powder, pass through a 300-mesh sieve, and set aside;

[0024] (3) Add an appropriate amount of magnesium stearate to the fine powder obtained in step (3) and make a soft material with starch slurry, pass through a 2...

Embodiment 2

[0026] (1) According to 20 parts of Polygonum cuspidatum, 15 parts of Plantaginaceae, 15 parts of Caulis Caulis, 10 parts of Cercis cerevisiae, 9 parts of Turmeric, 10 parts of Caulis Spatholobus, 10 parts of Chinese yam, and 10 parts of Cuscuta chinensis, weigh the Chinese herbal medicines, cleanly select, Crushed into coarse powder, set aside;

[0027] (2) Add 11 times the amount of water to the coarse powder obtained in step (1), heat it to boiling, decoct with low heat for 4 hours, filter to obtain the filtrate, add 9 times of water to the filter residue and decoct twice, each time for 3.5 hours, filter , combined the filtrates, concentrated to a thick paste, placed in a vacuum drying oven, dried at 70°C to obtain a dry extract, crushed the dry extract into fine powder, passed through a 300-mesh sieve, and set aside;

[0028] (3) Add an appropriate amount of magnesium stearate to the fine powder obtained in step (3) and make a soft material with starch slurry, pass through...

Embodiment 3

[0030] (1) According to 15 parts of Polygonum cuspidatum, 12 parts of Plantaginaceae, 10 parts of Caulis Caulis, 11 parts of Lumigrass, 12 parts of Turmeric, 8 parts of Caulis Spatholobus, 6 parts of Chinese yam, and 8 parts of Cuscuta, weigh the Chinese herbal medicines, and cleanly select them. Crushed into coarse powder, set aside;

[0031] (2) Add 9 times the amount of water to the coarse powder obtained in step (1), heat it to boiling, decoct with low heat for 3 hours, filter to obtain the filtrate, add 7 times of water to the filter residue and decoct twice, each time for 2.5 hours, filter , combine the filtrates, concentrate to a thick paste, place in a vacuum drying oven, and dry at 65°C to obtain a dry extract, crush the dry extract into fine powder, pass through a 300-mesh sieve, and set aside;

[0032] (3) Add an appropriate amount of magnesium stearate to the fine powder obtained in step (3) and make a soft material with starch slurry, pass through a 20-mesh sieve ...

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Abstract

The invention provides application of a Chinese medicine composition to the preparation of medicine for treating chronic gout. The Chinese medicine composition is prepared by polygonum cuspidatum, semen plantaginis, caulis piperis futokadsurae, pyrola, radix curcuma, caulis spatholobi, rhizoma dioscoreae and semen cuscutae through water extraction. The Chinese medicine composition has the advantages that the polygonum cuspidatum and the semen plantaginis having the effect of clearing heat and promoting diuresis are used as the monarch drugs, the caulis piperis futokadsurae and the pyrola having the effect of dispelling wind and removing meridian obstruction are used as the ministerial drugs, the radix curcuma and the caulis spatholobi having the effect of promoting blood circulation to arrest pain and the rhizoma dioscoreae and the semen cuscutae having effects of tonifying qi and the spleen and nourishing the liver and the kidney are also used, and the Chinese medicine composition has an evident curative effect on the gout and hyperuricemia and is low in toxic and side effect and suitable for being taken by a patient for a long time.

Description

technical field [0001] The invention relates to an application of a traditional Chinese medicine composition in preparing medicine for treating chronic gout, and belongs to the field of traditional Chinese medicine application. Background technique [0002] Gout is a characteristic joint inflammation caused by the disorder of purine metabolism and the increase of blood uric acid, which leads to the deposition of uric acid crystals in the joints and the tissues around the joints. Clinically, it is characterized by hyperuricemia, recurrent episodes of characteristic acute arthritis, and gout stone formation. In severe cases, it can cause joint deformity and dysfunction, acute obstructive nephropathy or gouty nephropathy. In recent years, due to the improvement of people's living standards and changes in diet structure, the incidence of gout has increased year by year. With the continuous research on the pathogenesis of gout, many drugs for the treatment of gout have also been ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P19/06
CPCA61K36/185A61K36/39A61K36/43A61K36/486A61K36/67A61K36/68A61K36/704A61K36/8945A61K36/9066A61K2236/331A61K2236/39A61K2236/51A61K2300/00
Inventor 韩洁茹张海丽解颖王书惠白吉祥
Owner HEILONGJIANG UNIV OF CHINESE MEDICINE
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