Intelligent equipment based HBV genotyping lateral flow multiplex reagent detection device

Abstract

The invention relates to an intelligent equipment based HBV genotyping lateral flow multiplex reagent detection device. The device includes intelligent equipment, a communication unit, a core control unit, a current regulation unit, an excitation light source and a high pass optical filter. The intelligent equipment communicates with the core control unit through a bluetooth communication way; the excitation light source is used for exciting the fluorescent substance on a lateral flow multiplex detection reagent, and the exciting light intensity is realized by setting the current regulation unit by the core control unit; and the intelligent equipment shoots the fluorescence image of the lateral flow multiplex detection reagent after passing through the high pass optical filter, image processing is carried out according to a built-in algorithm, the genotype of a to-be-detected sample on the lateral flow multiplex detection reagent is judged, and finally the detection result is displayed. The intelligent equipment is adopted as the system software and image analysis carrier, the structure of the HBV genotyping device is simplified, the detection device has the advantages of small volume, quick detection, simple operation, low cost, and easy promotion, and the detection result can be uploaded to various medical institutions through a wireless network of the intelligent equipment.

Description

technical field [0001] The invention relates to the field of biomedical detection, in particular to an intelligent device-based HBV genotyping lateral flow multiple reagent detection device, in particular to fluorescence-based medical detection. Background technique [0002] Hepatitis B virus (HBV) is one of the hepatitis viruses that seriously endanger human health and is an important pathogenic factor of the liver. HBV genotyping has very important guiding significance for predicting prognosis, evaluating response to drug treatment, and selecting treatment options. [0003] At present, the HBV genotyping method is mainly based on the principle of nucleic acid gene analysis, that is, the DNA sequence of the hepatitis B virus is first amplified, and then the amplified DNA sequence is detected and analyzed to determine its genotype. This method first needs to rely on PCR (Polymerase Chain Reaction, polymerase chain reaction) amplification reaction to obtain enough DNA fragme...

AI Technical Summary

Problems solved by technology

This method first needs to rely on PCR (Polymerase Chain Reaction, polymerase chain reaction) amplification reaction to obtain enough DNA fragments of hepatitis B virus, and then adopts methods such as hybridization, fluorescent labeling to detect, and the disadvantage of this method is: Difficult to popularize due to many testing equipments, long time, complicated operation and high cost

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