Micro-fluidic chip capable of producing two kinds of droplets including oil-water-oil droplets and water-oil-water droplets

Abstract

The invention relates to a micro-fluidic chip capable of producing two kinds of droplets including oil-water-oil droplets and water-oil-water droplets. The micro-fluidic chip comprises a first hydrophobic layer, a second hydrophobic layer, a first hydrophillic layer and a second hydrophillic layer; a first through hole, a second through hole, a third through hole and a fourth through hole penetrate through the surface of the first hydrophobic layer; a fifth through hole, a sixth through hole, a seventh through hole and an eighth through hole penetrate through the surface of the second hydrophobic layer; a first microchannel unit is formed in the left part of the upper surface of the second hydrophobic layer; a second microchannel unit is formed in the right part of the upper surface of the second hydrophobic layer; a ninth through hole, a tenth through hole, an eleventh through hole and a twelfth through hole penetrate through the surface of the first hydrophillic layer; and a cross channel is formed in the lower surface of the first hydrophillic layer. The micro-fluidic chip solves the problem that at present, no micro-fluidic chip integrating two or more materials can prepare both the oil-water-oil droplets and the water-oil-water droplets exists and is suitable for the fields of biological detection, drug screening, cell research, material synthesis and the like.

Description

technical field [0001] The invention relates to a microfluidic chip, in particular to a microfluidic chip capable of generating oil-water-oil and water-oil-water droplets. Background technique [0002] The microfluidic chip integrates or basically integrates the basic operation units such as sample preparation, separation, mixing, reaction and detection involved in the fields of biology and chemistry into a chip of a few square centimeters (or even smaller), relying on the chip. Functional devices such as micro-pipes, micro-valves, liquid reservoirs, micro-electrodes, micro-detection elements, and connectors control fluid throughout the entire system, and are used to replace a technical platform for various functions of conventional biological or chemical laboratories, so it is also called For the lab-on-a-chip (lab-on-a-chip). The microfluidic chip can integrate the sampling, dilution, concentration, mixing, separation, reaction and detection of routine experiments into fu...

AI Technical Summary

Problems solved by technology

[0005] At present, chips for preparing water-oil-water and oil-water-oil droplets generally use one material, and the surface hydrophilic and hydrophobic properties of a single material are fixed, which requires modification of the surface, resulting in The following problems: First, the process of surface modification is cumbersome, and it is necessary to protect the parts that do not need to be modified during the modification process

However, there is currently no such droplet microfluidic chip

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