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A compound for treating cancer and its preparation and use

A complex and cancer technology, applied in the direction of medical preparations containing active ingredients, drug combinations, pharmaceutical formulas, etc., can solve the problem of artemisinin antimalarial drugs and aminoquinoline antimalarial drug compounds, There are no issues such as undisclosed therapeutic uses of the complex, and the effects of improving therapeutic effects, low side effects, and reducing occurrence and development are achieved

Active Publication Date: 2019-06-07
普罗布诺(重庆)生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The prior art discloses many complexes containing antimalarial drugs for the treatment of cancer, but the prior art does not disclose complexes composed of artemisinin antimalarials and aminoquinoline antimalarials, nor No therapeutic use of this complex has been disclosed

Method used

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  • A compound for treating cancer and its preparation and use
  • A compound for treating cancer and its preparation and use
  • A compound for treating cancer and its preparation and use

Examples

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Comparison scheme
Effect test

Embodiment 1

[0051] Embodiment 1 A compound for treating cancer

[0052] The complex includes artemisinin and chloroquine, and the molar ratio of artemisinin and chloroquine is 0.1:100.

Embodiment 2

[0053] Embodiment 2 A compound for treating cancer

[0054] The complex includes artemisinin and chloroquine, and the molar ratio of artemisinin and chloroquine is 100:0.1.

Embodiment 3

[0055] Embodiment 3 A compound for treating cancer

[0056] The complex includes artemisinin and chloroquine, and the molar ratio of artemisinin and chloroquine is 1:1.

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Abstract

The invention provides a composition prepared from artemisinin antimalarials and aminoquinoline antimalarials; the composition is suitable for treating the cancers, such as lung cancer, breast cancer and melanoma, has low side effect, and is effective in improving cancer treatment effect and reducing the development and progress of a patient's complications.

Description

technical field [0001] The invention belongs to the field of pharmaceutical preparations containing organic active ingredients, and in particular relates to a compound for treating cancer and its preparation and application. Background technique [0002] Cancer is one of the most important diseases threatening human health, and its publication rate is increasing year by year. Among them, lung cancer and breast cancer are the most common malignant tumors. The current main treatment for cancer is chemotherapy. There are many anticancer drugs on the market, including alkylating agents, antimetabolites, and antitumor antibiotics, but most of these drugs are not tolerated by patients due to their high toxicity. With the continuous development of science and technology, the continuous change of lifestyle, and the rising incidence and mortality of cancer, it is imminent to study drugs for the treatment of cancer. [0003] Artemisinin is a sesquiterpene lactone isolated from the ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/4706A61K31/366A61K31/357A61K31/496A61P35/00
CPCA61K31/357A61K31/366A61K31/4706A61K45/06A61P35/00A61K2300/00
Inventor 饶栓
Owner 普罗布诺(重庆)生物技术有限公司