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Chinese and western medicinal composition for treating radioactive enteritis, and preparation method and application thereof

A technology for radiation enteritis and Chinese and Western medicine, applied in the field of medicine, to achieve the effects of short production cycle, easy availability of raw materials and low price

Inactive Publication Date: 2017-02-22
郑州莉迪亚医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no effective Chinese and Western medicine composition or method for treatment. Most of the medical institutions use symptomatic treatment, and the Chinese and Western medicine compositions used are also different. Most of them use Western medicine for symptomatic treatment, such as giving anti-inflammatory and analgesic, rehydration and antidiarrheal, etc.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] In the embodiment of the present invention, a Chinese and Western medicine composition for treating radiation enteritis is composed of the following raw materials in parts by weight: 3 parts of sodium alendronate, 11 parts of bromhexine, 5 parts of taurine, and 1 part of calcium lactate .

[0019] Mix alendronate sodium, bromhexine, and calcium lactate, add deionized water 3.1 times the mass of the three, raise the temperature to 75°C, and stir at this temperature for 38 minutes to prepare mixture A. The mixture A was mixed with taurine, ultrasonically treated for 25 minutes at a temperature of 58° C. with an ultrasonic power of 900 W, and then stirred until dry at a temperature of 63° C. to obtain a Chinese and western medicine composition.

Embodiment 2

[0021] In the embodiment of the present invention, a Chinese and Western medicine composition for treating radiation enteritis is composed of the following raw materials in parts by weight: 7 parts of sodium alendronate, 19 parts of bromhexine, 13 parts of taurine, and 5 parts of calcium lactate .

[0022] Mix alendronate sodium, bromhexine, and calcium lactate, add deionized water 3.1 times the mass of the three, raise the temperature to 77°C, and stir at this temperature for 40 minutes to prepare mixture A. The mixture A was mixed with taurine, ultrasonically treated for 25 minutes at a temperature of 58° C. with an ultrasonic power of 900 W, and then stirred until dry at a temperature of 63° C. to obtain a Chinese and western medicine composition.

Embodiment 3

[0024] In the embodiment of the present invention, a Chinese and Western medicine composition for treating radiation enteritis is composed of the following raw materials in parts by weight: 4 parts of sodium alendronate, 13 parts of bromhexine, 7 parts of taurine, and 2 parts of calcium lactate .

[0025] Mix alendronate sodium, bromhexine, and calcium lactate, add deionized water 3.1 times the mass of the three, raise the temperature to 76°C, and stir at this temperature for 39 minutes to prepare mixture A. The mixture A was mixed with taurine, ultrasonically treated for 25 minutes at a temperature of 58° C. with an ultrasonic power of 900 W, and then stirred until dry at a temperature of 63° C. to obtain a Chinese and western medicine composition.

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PUM

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Abstract

The invention discloses a Chinese and western medicinal composition for treating radioactive enteritis, and a preparation method and application thereof. The Chinese and western medicinal composition comprises, by weight, 3-7 parts of alendronate sodium, 11-19 parts of bromhexine, 5-13 parts of taurine and 1-5 parts of calcium lactate. The preparation method includes mixing the alendronate sodium with the bromhexine and the calcium lactate, adding deionized water, increasing the temperature to 75-77 DEG C, and stirring the raw materials for 38-40 minutes to obtain a mixture A; mixing the mixture A with the taurine, performing ultrasonic treatment at the temperature of 58 DEG C for 25 minutes, and performing stirring at the temperature of 63 DEG C until drying to obtain the Chinese and western medicinal composition, wherein the ultrasonic power is 900W. The Chinese and western medicinal composition has a unique formula and low price, is safe and convenient, has better effect than regularly-used western medicine, can effectively treat colon and rectum injuries caused by radiotherapy, has high cure rate and quick action and is free from toxic and side effect; recurrence of the radioactive enteritis is avoided after curing; the preparation process is simple, raw materials are simple and easy to get, production cycle is short, cost is low, and the Chinese and western medicinal composition is suitable for industrial production and large-scale popularization.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a traditional Chinese and western medicine composition for treating radiation enteritis and its preparation method and application. Background technique [0002] Radiation enteritis is an intestinal complication caused by radiotherapy for malignant tumors in the pelvic cavity, abdominal cavity, and retroperitoneum. The small intestine, colon, and rectum can be involved respectively, so it is also called radiation rectum, colon, and enteritis. Radiation sickness is generally divided into two types: acute and chronic, according to the radiation dose, time, and severity of the intestinal tract. According to the different positions inside and outside the body where the radiation source is placed, it can be divided into external radiation sickness and internal radiation sickness. In the early stage, the renewal of intestinal mucosal cells is inhibited, and later the arteriole wall ...

Claims

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Application Information

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IPC IPC(8): A61K31/663A61K31/191A61K31/185A61K31/137A61P1/00
CPCA61K31/663A61K31/137A61K31/185A61K31/191
Inventor 不公告发明人
Owner 郑州莉迪亚医药科技有限公司
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