47 results about "Radiation Enteritis" patented technology

The present invention provides conformationally-defined macrocyclic compounds that bind to and / or are functional modulators of the motilin receptor including subtypes, isoforms and / or variants thereof. These macrocyclic compounds, at a minimum, possess adequate pharmacological properties to be useful as therapeutics for a range of disease indications. In particular, these compounds are useful for treatment and prevention of disorders characterized by hypermotilinemia and / or gastrointestinal hypermotility, including, but not limited to, diarrhea, cancer treatment-related diarrhea, cancer-induced diarrhea, chemotherapy-induced diarrhea, radiation enteritis, radiation-induced diarrhea, stress-induced diarrhea, chronic diarrhea, AIDS-related diarrhea, C. difficile associated diarrhea, traveller's diarrhea, diarrhea induced by graph versus host disease, other types of diarrhea, dyspepsia, irritable bowel syndrome, chemotherapy-induced nausea and vomiting (emesis) and post-operative nausea and vomiting and functional gastrointestinal disorders. In addition, the compounds possess utility for the treatment of diseases and disorders characterized by poor stomach or intestinal absorption, such as short bowel syndrome, celiac disease and cachexia. The compounds also have use for the treatment of inflammatory diseases and disorders of the gastrointestinal tract, such as inflammatory bowel disease, ulcerative colitis, Crohn's disease and pancreatitis. Accordingly, methods of treating such disorders and pharmaceutical compositions including compounds of the present invention are also provided.

The invention discloses an enema for treating radiation proctitis. Radiation enteritis belongs to the category of "diarrhea" and "dysentery" in traditional Chinese medicine. For this reason, the present invention selects to have with heat-clearing and toxic substances removing, detumescence and hemostasis, the Chinese medicine narcissus, purple ginseng, cassia root, cassia seed, toon alba, nasturtium, purple pearl leaf, big thistle, lotus leaf, Sophora japonica, Mulberry fruit, Atractylodes macrocephala, longan core, and honey are used to make enemas. Through clinical trials in our hospital, the total effective rate of the treatment group is 91.3%, which is better than that of the control group, which is 78.3%. No side effects, worthy of clinical application.