Compound medicine with antioxidant function and preparation method thereof

An anti-oxidation and compound technology, which is applied in the direction of medical preparations containing active ingredients, drug combinations, anti-toxins, etc., can solve the problems of low antioxidant capacity and disease, achieve strong ability to scavenge free radicals, improve extraction rate, Effect of enhancing antioxidant function

Active Publication Date: 2017-04-26
LANZHOU UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Now, as the air environment is getting worse, people with low antioxidant capacity are always facing the risk of being overly attacked by free radicals and getting sick

Method used

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  • Compound medicine with antioxidant function and preparation method thereof
  • Compound medicine with antioxidant function and preparation method thereof

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preparation example Construction

[0031] This embodiment also provides a preparation method of a compound drug with antioxidant function, which includes:

[0032] S1: Mix the raw materials in parts by weight, extract the mixed raw materials by solvent extraction, filter and concentrate to obtain the extract.

[0033] Further, the solvent extraction method includes any one of decoction method, percolation method, heating reflux method, and microwave extraction method. The solvent used in the extraction is water or ethanol, or a mixture of water and alcohol. When the heating and reflux method is used for extraction, preferably, the mixture of raw materials is refluxed and extracted at 60-80°C for 1-3 times, each time for 1-3h, and then the obtained extracts are combined and concentrated to obtain Extract.

[0034] More preferably, the solvent extraction method is a decoction method, and the decoction method includes: soaking the mixed raw medicine in water for 1.5 to 2.5 hours, heating and boiling to obtain an...

Embodiment 1

[0040] This embodiment provides a compound drug with antioxidant function, the preparation method of which comprises:

[0041]a. Raw material preparation: take bulk medicine and Codonopsis selenium polysaccharide, the quality of Codonopsis selenium polysaccharide is 0.05 times of bulk medicine. Wherein, the content of selenium in Codonopsis selenium polysaccharide is 1000 μg / g; the raw material medicine includes 40 parts by weight of Codonopsis pilosula, 20 parts of angelica, 10 parts of wolfberry, 20 parts of asparagus and 5 parts of rhubarb.

[0042] b. Extraction: Mix the raw materials, and extract the mixed raw materials by decoction, that is, soak the mixed raw materials in water for 2.5 hours, heat and boil to obtain the extract; decoct twice in total, each time The decoction time is 0.8h, add 8 times the water of the raw material drug for the first time, add 6 times the water of the raw material drug for the second time, then combine the obtained extracts, and concentra...

Embodiment 2

[0045] This embodiment provides a compound drug with antioxidant function, the preparation method of which comprises:

[0046] a. Raw material preparation: take bulk medicine and Codonopsis selenium polysaccharide, the quality of Codonopsis selenium polysaccharide is 0.1 times of bulk medicine. Among them, the Codonopsis selenium polysaccharide is extracted from Codonopsis pilosula planted in selenium-rich soil, and the content of selenium in the Codonopsis selenium polysaccharide is 500 μg / g; the raw material medicine includes 45 parts by weight of Codonopsis pilosula, 15 parts of angelica, and 15 parts of wolfberry , asparagus 15 parts and rhubarb 10 parts.

[0047] b. Extraction: mix the raw materials, and extract the mixed raw materials by decoction, soak the mixed raw materials in water for 2 hours, heat and boil to obtain the extract; decoct 3 times in total, each time The decocting time is 1h, the water of 8 times of raw materials is added for the first time, the water...

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Abstract

The invention provides a compound medicine with an antioxidant function and a preparation method thereof and belongs to the field of Chinese pharmaceutical manufacturing. The compound medicine is prepared by mixing extracts of raw medicines and pilose asiabell root selenium-containing polysaccharide, wherein the mass ratio of the extracts to the pilose asiabell root selenium-containing polysaccharide is 1:(0.05-0.2). The raw medicines comprise pilose asiabell roots, radix angelicae sinensis, fructus lycii, cochinchnese asparagus roots and radix et rhizoma rhei. The compound medicine has a strong ability of scavenging free radicals and can treat or relieve various diseases caused by low antioxidant capacity of a body. The preparation method comprises the following steps that the raw medicines are mixed by weight parts, and the mixed raw medicines are extracted by means of a solvent extraction method, filtered and concentrated to obtain the extracts; the extracts are mixed with the pilose asiabell root selenium-containing polysaccharide to obtain a mixture, and the obtained mixture is prepared into a medicament. The method adopts the solvent extraction method to extract the raw medicines for further mixing with the pilose asiabell root selenium-containing polysaccharide, the process is simple, and the method is suitable for massive production.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a compound medicine with anti-oxidation function and a preparation method thereof. Background technique [0002] The human body continuously generates free radicals in the human body due to continuous contact with the outside world, including breathing, external pollution, radiation exposure and other factors. Scientific studies have shown that cancer, aging or other diseases are mostly associated with the production of excess free radicals. Now, as the air environment is getting worse, people with low antioxidant capacity are always facing the risk of being overly attacked by free radicals and getting sick. In view of this, the present invention provides a new drug with antioxidant function. Contents of the invention [0003] The first object of the present invention is to provide a compound drug with anti-oxidation function. The compound drug has a strong ability...

Claims

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Application Information

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IPC IPC(8): A61K36/8965A61P39/06A61K31/715
CPCA61K31/715A61K36/232A61K36/344A61K36/708A61K36/815A61K36/8965A61K2236/331A61K2236/39A61K2300/00
Inventor 胡芳弟苟于强胡林海郑晓萍
Owner LANZHOU UNIVERSITY
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