48results about How to "Strong ability to scavenge free radicals" patented technology

The invention relates to a traditional Chinese medicine composition playing roles of stopping bleeding, diminishing inflammations and preventing bacteria and a toothpaste containing the traditional Chinese medicine composition. The traditional Chinese medicine composition comprises the following components: a cordyceps militaris extract, a pseudo-ginseng extract, a scutellaria baicalensis extract and tea polyphenol. The composition provided by the invention plays roles in stopping bleeding, diminishing inflammations and preventing bacteria, and can be applied to the toothpaste to prevent oral diseases.

The invention discloses a mineral water gloss stock solution containing fullerene. The mineral water gloss stock solution is prepared from the following raw materials: water, oligopeptide-1, butyleneglycol, betaine, hydroxyethylurea, bio-saccharide gum-1, glycerol, fullerene, rose flower water, trehalose, a bacillus fermented product, a saccharomycetes fermented product, tranexamic acid, sodium hyaluronate, magnolia biondii flower bud / flower extract, peppermint leaf extract, nicotinamide, 1,2-hexanediol, 1-methylhydantoin-2-imide, hamamelis virginiana extract, caesalpinia spinosa gum, xanthangum, dextrin and allantoin. The water gloss stock solution disclosed by the invention has good effects of cleaning free radicals, whitening and moisturizing.

The invention discloses a chalcone derivative with good anti-free radical oxidative damage activity. The structural formula of the chalcone derivative is shown as the following. The preparation method of the chalcone derivative includes: letting syringaldehyde and para-substituted acetophenone react in piperidine and under a high temperature so as to generate corresponding substituted chalcone; reacting purified chalcone with sodium borohydride under a cerous chloride heptahydrate condition to generate a chalcone derivative crude product, and then conducting purification. , Compared with ascorbic acid, the product provided by the invention has low anti-DPPH free radical and anti-ABTS<+> free radical IC50 value, and strong free radical scavenging ability, thus having broad application prospects in preparing drugs for treating neurodegenerative diseases. (formula I).

The invention discloses a skin care product with moisturizing, soothing and oxidation-resisting functions. Mauritia flexuosa fruit oil, simmondsia chinensis seed oil, avocado oil, tocopherol, aloe barbadensis leaf extracts, chamomilla recutita flower extracts, malva sylvestris flower extracts, peony root extracts, lonicera japonica flower extracts, dandelion rhizome / root extracts, herba violae extracts, aloe barbadensis leaf juice, sodium hyaluronate and bio-saccharide gum-1 serve as main components, and auxiliary materials are added to prepare the skin care product. The skin care product hasremarkable moisturizing effects, strong free radical removing capacity and prominent soothing effects. The invention further discloses a preparation method of the skin care product. The preparation method is simple in technology, low in equipment requirement and suitable for industrial production.

The invention discloses a Tibetan medicinal extract skin-care product and a preparation method thereof. The skin-care product comprises the following raw materials in percentage by weight: 7-10% of gentiana macrophylla extract, 3-5% of sapodilla extract and 3-5% of senecio cineraria extract. The skin-care product comprises facial cleanser, essence and emulsion. The main raw materials are Tibetan medicaments, so the skin-care effect is good and the value of the Tibetan medicament can be sufficiently utilized.

The invention provides light-colored melanin sunscreen cream and a preparation method thereof. The sunscreen cream is a cross-linked product of a polydopamine oligomer and a hydrophilic polymer with sulfydryl, amino or boric acid; the polydopamine oligomer has a molecular weight of 2k-8k, and the hydrophilic polymer with sulfydryl, amine or boric acid is a multi-arm boric acid PEG or a multi-arm sulfydryl PEG. The gelation pH value of the sunscreen cream is 7-9, the gelatinization temperature is room temperature, and the gelation time is 5s-300s. The preparation method comprises the following steps: step 1, carrying out oxidative self-polymerization of dopamine hydrochloride in alkaline and air; step 2, separating an intermediate oligomer by means of dialysis; and step 3, mixing and cross-linking the oligomer obtained in the step 2 with the hydrophilic polymer with sulfydryl, amino or boric acid to obtain the sunscreen cream. The light-colored melanin sunscreen cream provided by the invention has ultraviolet absorption and low visible light absorption functions, has good skin retention ability, can be mechanically erased by towel, has good biological stability, has no skin penetration, and has good free radical scavenging ability.

The invention discloses an antihyperglycemic tea for body-building, which is prepared from green tea and Chinese medicinal composition fluid extract by the weight ratio of 1:1.2-1.8, and the Chinese medicinal composition fluid extract is prepared from (by weight ratio) haw 6-40 parts, alisol 5-30 parts, giant knotweed rhizome 6-40 parts, ginseng 1-7 parts, gynostemma pentaphylla 1-7 parts, dioscorea septemloba thunb. 0-10 parts, and prepared fleece-flower root 0-30 parts. The tea has the functions of resisting atherosclerosis and regulating blood pressure.

The invention relates to the technical field of microbial fermentation, in particular to a green tea fermentation filtrate and a preparation method and an application thereof. The present invention provides a green tea fermentation filtrate which is a fermentation culture product comprising a green tea extract, a carbon source, a nitrogen source, and a raw material mixture of yeast. The inventionalso provides the preparation method of the green tea fermentation filtrate, which comprises the following steps: (1) strain activation, (2) strain purification, (3) strain expanded culture, (4) inoculation fermentation, (5) ) clarification treatment, and (6) sterilization. The green tea fermentation filtrate of the invention does not contain any chemical components, and no additional enzyme or other processing aid is added during the production process, the production cost is small, and the production steps are simple. The product has the pleasant fermentation scent and good green color and clarity. The fermentation filtrate has the strong ability to scavenge free radicals, and the effect of inhibiting tyrosinase is remarkable.

The invention relates to an extraction method of nonextractable polyphenol in blueberry, and belongs to the technical field of extraction of plant polyphenol. The extraction method comprises the followings steps: preparing blueberry residue, preparing blueberry residue powder, performing acid solution soaking, performing alkali solution soaking, performing enzymolysis, centrifugation, extraction and collecting extractive. The extraction method is simple in operation steps, the operation steps can be performed in one container, and the extractive is not required to be repeatedly collected; weak concentration acid and alkali are adopted to treat materials, ethyl acetate and ethyl alcohol mixed liquor can be utilized for extracting, the method is mild, the bioactivity of the nonextractable polyphenol can be furthest reserved, the extraction ratio is improved, and the environmental pollution is very small.

The invention discloses a composition for reducing skin wrinkles and a cosmetic product thereof, and belongs to the technical field of cosmetics. The invention aims to provide a composition, which iscapable of effectively scavenging free radicals, strongly resisting oxidation, promoting collagen synthesis, and delaying skin aging. The composition mainly comprises the following components in partsby weight: 5-10 parts of a ginseng root extract, 2-7 parts of a myrciaria dubia fruit extract, 2-6 parts of a sphingomonas fermentation product extract and 0.5-3 parts of a buckbean leaf extract.

The invention discloses a honey refining method suitable for honey boluses. The honey refining method suitable for the honey boluses comprises the steps that (1) honey is selected as a raw material; (2) the raw material honey is sucked into a jacketed kettle, a steam valve of the jacketed kettle is opened, and steam is led into an interlayer under continuous stirring, the honey is heated to 75-85 DEG C, refined for 5-15 h, continuously heated to 105-120 DEG C, decocted for 0.5-2 h, and held for 5-15 h after the steam valve is closed; (3) the stewed honey is filtered through a sieve, and then conveyed to a vacuum evaporator; (4) concentration refining is conducted in the vacuum evaporator under the negative pressure condition, a photoelectric refractometer is observed, and moisture is controlled; and (5) the refined honey is conveyed into a honey storage pot. The honey refining method combines jacketed kettle steam atmospheric pressure heating with vacuum decompression concentration, and is good in stability, low in medical composition loss in the preparation process, high in quality and easy to operate.

The invention discloses a preparation method of wolfberry health table salt. The preparation method comprises the following steps of 1, wolfberry pretreatment, 2, supercritical CO2 extraction: carrying out supercritical CO2 extraction on the wolfberry powder obtained by the step 1 to obtain a wolfberry functional component, and 3, recrystallization: dissolving the wolfberry functional component obtained by the step 2 in a pure aqueous solution at a normal temperature under normal pressure, dissolving common salt in the solution until saturation and carrying out pressure reduction evaporation to obtain the wolfberry health table salt crystals. The preparation method uses wolfberry powder extract in commercial table salt, maximumly utilizes wolfberry health care effects and realizes seasoning and health improvement.

The invention discloses a making method of steam heat-treated sorghum whole-flour steamed bread. Due to the excessive contents of tannin and insoluble dietary fibers in sorghum, the eating quality ofthe sorghum is limited. Sorghum raw materials are treated through a steam heat-treatment technology, that is, the sorghum raw materials are treated through the high temperature, the high pressure andthe short time, the contents of the tannin and the insoluble dietary fibers can be effectively decreased, and the contents of substances such as polyphenols and resistant starch in the sorghum can beeffectively decreased. The sorghum raw materials are subjected to steam heat-treatment and made into sorghum whole flour, the sorghum whole flour is added into wheat flour according to the principle that the adding amount of the sorghum whole flour accounts for 1%-50% of the ratio (the quality ratio of the steam heat-treated sorghum whole flour accounting for mixed flour) so as to be made into thesteam heat-treated sorghum whole flour steamed bread, and the palatability and the continuous eating property are greatly improved. The steam heat-treated sorghum whole flour is added into flour products so that the nutrition loss caused by the overhigh processing accuracy of wheat can be well supplemented, and application of the sorghum to main food processing is expanded.

The invention specifically relates to a preparation method and novel application of a novel isoflavonoid compound, belonging to the fields of medicine and chemistry of natural products. The isoflavonoid compound provided by the invention has a general structural formula as described in the specification. In the general structural formula, R1 and R2 have one to five glycosyl groups and may be H, (CH2)nCH3, or OR' (wherein R' may be H or (CH2)nCH3 and has one to five glycosyl groups); R3 and R4 may be H, (CH2)nCH3, or OR' (wherein R' may be H or (CH2)nCH3 and has one to five glycosyl groups); the glycosyl group is a glucosyl group or apiosyl group; and n is in a range of 0 to 3. The isoflavonoid compound provided by the invention has substantial antioxidation activity.

The invention relates to a preparation method and application of deep sea extracellular polymeric substances. The preparation method comprises the following steps of: (1) inoculating a deep-sea bacterium SM-A87 stain to a liquid seed culture medium, carrying out shake culture for 2-3 days, then inoculating the stain to a fermentation culture medium for culturing for 20-30h, adjusting the fermentation temperature, and continuously culturing for 8-10 days to prepare a fermentation liquor; (2) adding absolute alcohol to the fermentation liquor for ethanol precipitation, separating to obtain a precipitate, washing the precipitate with absolute alcohol, and drying to obtain crude polysaccharide; (3) dissolving the crude polysaccharide into water, adding alkali protease for enzymolysis for 5-6h; and adding absolute alcohol for ethanol precipitation, separating to obtain a precipitate, washing the precipitate with absolute alcohol, and drying to prepare the deep-sea extracellular polymeric substances. The deep-sea extracellular polymeric substances prepared by the method have good moisture absorption and preservation properties and oxidation resistance and have a good application potential in the field of cosmetics.

The invention relates to a polaribacter sp. and an application. Luojia Mountain in Wuchang district, Wuhan, China, and the preservation number is CCTCC No. M2013437. The bacterial strain can secrete a lot of polaribacter sp extracellular polysaccharide. The polysaccharide has good rheology property, is capable of absorbing moisture, preserving moisture, removing activity of organic free radical, hydroxyl radical and oxyradical, and has the characteristics of non toxicity and no stimulation.

The invention discloses ray chondroitin sulfate and an extraction method thereof. An ultrasonic-assisted alkali salt-enzymolysis method is adopted, and the optimal process conditions are as follows: the concentration of alkali liquor is 2.3%, the extraction temperature is 43 DEG C, the enzyme addition amount is 0.7%, the ultrasonic extraction time is 180 minutes, the enzymolysis temperature is 45DEG C, the enzymolysis time is 12 hours, the optimal extraction rate can reach 43.32%, and the purity reaches 94%. The characteristic components of the ray CS are 4-monosulfated disaccharide CS-A, 6-monosulfated disaccharide CS-C and 2, 6-disulfated disaccharide CS-C, the ray CS is different from shark chondroitin in the aspect of A / C (CS-A / CS-C content ratio), and the ray CS not only has the potential of serving as a good shark CS substitute, but also shows physiological activity and functions different from those of shark CS due to the outstanding characteristics. The content of sulfate radicals in the ray chondroitin sulfate reaches 17.18%, the ray chondroitin sulfate is highly sulfated chondroitin polysaccharide, the oxidation resistance of the ray chondroitin sulfate is obviously higher than that of CS with a low sulfation degree, and the ray chondroitin sulfate has high free radical scavenging capacity.

Provided are a light-colored melanin sunscreen and a preparation method thereof. Sunscreen is a cross-linked product of polydopamine oligomers and hydrophilic polymers with sulfhydryl groups, amino groups or boronic acids; the molecular weight of polydopamine oligomers is 2k‑8k, and hydrophilic polymers with sulfhydryl groups, amino groups or boronic acids It is multi-arm boronic acid PEG or multi-arm thiol PEG. The gelling pH of the sunscreen is 7‑9, the gelling temperature is room temperature, and the gelling time is 5s‑300s. The preparation method comprises the following steps, step 1, oxidative self-polymerization of dopamine hydrochloride in alkali and air; step 2, separating the middle oligomer by dialysis; step 3, combining the oligomer obtained in step 2 with Hydrophilic polymers with mercapto groups, amino groups or boric acids are mixed and cross-linked to obtain sunscreens. The light-colored melanin sunscreen of the present invention has UV absorption but low visible light absorption; has good skin retention and can be mechanically wiped off by towel; has good biological stability and no skin penetration; has good Ability to scavenge free radicals.

The invention discloses a flaxseed nutritive sport drink for teenagers. The flaxseed nutritive sport drink consists of the following raw materials in parts by weight of 18-30 parts of a flaxseed extracting solution, 4-6 parts of strigose hydrangea juvenile leaf total polyphenol, 4-8 parts of red bean polysaccharide, 2-3 parts of cane sugar, 2-4 parts of honey, 0.1-0.2 part of citric acid, 0.05-0.1part of xanthan gum, 0.1-0.2 part of CMC-Na, 0.1-0.2 part of sodium alginate, 0.6-1.3 parts of complex vitamins, 0.1-0.5 part of minerals, 0.002-0.004 part of essence, 0.001-0.003 part of ethyl maltol, and the balance of water, wherein all of the raw materials are 150 parts. The drink can complement energy and nutrient substances for the teenagers, can assist in relieving sports fatigue for the teenagers, can improve the athletic ability, can enable drinkers to restore physical work capacity rapidly, and besides, can prevent the teenagers from suffering from obesity, can strengthen the constitutions of the teenagers, and can improve immunity.

The invention discloses combined buccal tablets for alleviating asthenopia and a preparation method thereof, and belongs to the field of vision health food. The combined buccal tablets are mainly prepared by mixing 14-16 parts of a soybean saponin crude extract, 16-18 parts of corn flour, 19-21 parts of crude anthocyanin powder, 10-12 parts of black fungus powder and 10-12 parts of physalis pubescens extract juice powder evenly and tabletting. Soxhlet extraction, ultrasonic assisted ethanol extraction, enzymolysis extraction, spray drying and other processes are combined, and the prepared combined buccal tablets for alleviating asthenopia has the DPPH clearance rate reaching 79.32% and the hydroxyl radical (HO.) clearance rate of 65.27%%, the asthenopia symptoms after trial eating is obviously improved, the effective rate reaches 80%, and the average vision-improving endurance is improved; the results show that the combined buccal tablets prepared from Northeast special food comprisingsoybean, corn, blueberry, black fungus and physalis pubescens has strong free radical scavenging ability and good effect of alleviating asthenopia.

The invention provides a rice peptide with a whitening function as well as a preparation method and an application thereof. The rice peptide at least comprises peptide fragments GS, GL and GF, based on the mass of the rice peptide, the content of the peptide fragment GS is greater than or equal to 200.00 mg / 100g, the content of the peptide fragment GL is greater than or equal to 200.00 mg / 100g, and the content of the peptide fragment GF is greater than or equal to 100.00 mg / 100g. The rice peptide containing the three peptide fragments of GS, GL and GF can significantly remove DPPH free radicals and OH free radicals, reduce the ROS content, melanin synthesis rate and tyrosinase activity in human skin melanocytes, and has strong antioxidant ability and whitening ability.

The invention relates to the technical field of medicine, and particularly relates to a medical radiation protection spray and a preparation method and a use method thereof. The medical radiation protection spray is mainly prepared from hippophae rhamnoides, rosa roxburghii tratt, folium mori, buckwheat, radix angelicae pubescentis, aloes, ulva, lavender, chamomile, flores aurantii, strawflower, rose bud, menthol, olive oil and trihytdroxy methyl-aminomethane and by the steps of material cleaning, high temperature extraction, petroleum ether ultrasonic extraction, ethanol-chloroform microwaveextraction, reduced pressure concentration, blending and filtering to remove bacteria. The medical radiation protection spray can quickly penetrate into the skin, can clear away superoxide radicals with stronger force, repair damaged cell tissues, promote tissue regeneration and epithelial tissue healing, and moisturize and increase skin elasticity lastingly, not only has good anti-wrinkle and moisturizing as well as regeneration and repair functions, but also has multiple efficacies of invigorating the circulation of blood and dispersing blood stasis, resisting bacteria and eliminating inflammation, so as to remarkably reduce harm of rays to the skin, is high in cure rate and rapid in effect, and is free of side effect and high in safety.

The invention belongs to the field of radiation protection, and specifically relates to nucleus-targeting fullerenol solid lipid nano-particles with a radiation protection function. The fullerenol solid lipid nano-particles comprises: stearic acid, cholesterol, lecithin, corn oil, Tween-80, fullerenol powder, and diethylstilbestrol. According to the invention, stearic acid, cholesterol, lecithin, corn oil, fullerenol powder, and diethylstilbestrol are sufficiently dissolved in ethanol; the mixture is well mixed; ethanol is removed by rotary evaporation; the mixture is slowly dropped into an aqueous solution of Tween-80 with a same temperature; when dropping is finished, the mixture is stirred and well mixed, such that C60(OH)24-SLN-E primary emulsion is obtained; the C60(OH)24-SLN-E primary emulsion is subject to high-pressure homogenizing, and is cooled, such that a required product is obtained. The fullerenol solid lipid nano-particles provided by the invention can penetrate various biological barriers and nuclear membranes, and carry fullerenol into nuclei with high efficiency. Therefore, free radicals in the nuclei can be removed, such that the radiation protection function can be realized.

The invention discloses a synthetic polypeptide with antioxidant effect and a gene encoding same, and a preparation method and application of the synthetic polypeptide. According to the invention, a Fmoc solid phase synthesis method is employed; solid-phase synthetic resin is used as a carrier; amino acids are coupled with the solid-phase synthetic resin one by one from the C terminal to the N terminal of the polypeptide according to the arrangement manner of an amino acid sequence under the action of a mixed coupling agent so as to synthesize resin containing a target polypeptide fragment; then outer-layer resin is pyrolyzed and a Fmoc protecting group at a side chain is removed under the action of a pyrolysis removing agent; and the target polypeptide is cut off from the solid-phase carrier and is subjected to separation and purification so as to obtain the polypeptide having antioxidant effect. The synthesis method of the invention is simple in operation, short in synthesis time, low in the amount of by-products and low in synthesis cost. The synthetic polypeptide of the invention has remarkable anti-oxidation activity in vitro and good effect, can be used for preparing health food and medicines related to oxidation resistance and aging alleviation, is high in safety and wide in an application scope, and has good market prospects.

The invention discloses a skin care composition for promoting yellow race skin metabolism and delaying aging, which is mainly prepared from the following substances in parts by weight: 7-10 parts of callicarpa nudiflora extract, 2-4 parts of red maple extract, 1-3 parts of magnolia grandiflora leaf extract, 1-3 parts of rhizoma curcumae longae extract, 5-7 parts of singli roxbrugh rose fruit extract, 1-2 parts of aspalathus linearis leaf extract, 0.5-1.5 parts of polypodium leucotomos extract and 0.5-0.7 part of usnea barbata glabrescens extract. The plant composition in the invention may comprehensively combat dynamic wrinkles and static wrinkles, pores and rough skins, and improve skin elasticity and toughness, realizing smooth skins which rejuvenate from the inside out.

The invention provides a compound medicine with an antioxidant function and a preparation method thereof and belongs to the field of Chinese pharmaceutical manufacturing. The compound medicine is prepared by mixing extracts of raw medicines and pilose asiabell root selenium-containing polysaccharide, wherein the mass ratio of the extracts to the pilose asiabell root selenium-containing polysaccharide is 1:(0.05-0.2). The raw medicines comprise pilose asiabell roots, radix angelicae sinensis, fructus lycii, cochinchnese asparagus roots and radix et rhizoma rhei. The compound medicine has a strong ability of scavenging free radicals and can treat or relieve various diseases caused by low antioxidant capacity of a body. The preparation method comprises the following steps that the raw medicines are mixed by weight parts, and the mixed raw medicines are extracted by means of a solvent extraction method, filtered and concentrated to obtain the extracts; the extracts are mixed with the pilose asiabell root selenium-containing polysaccharide to obtain a mixture, and the obtained mixture is prepared into a medicament. The method adopts the solvent extraction method to extract the raw medicines for further mixing with the pilose asiabell root selenium-containing polysaccharide, the process is simple, and the method is suitable for massive production.

The invention belongs to the field of medicine and discloses a diosmin-copper(II) complex and a preparation method and application thereof. The diosmin-copper(II) complex has a chemical formula of [Cu(DM)2(H2O)2] 1.5H2O, wherein DM is diosmin; the specific structural formula is shown in the description. The antitumor activity of the diosmin-copper(II) complex is studied by means of a MTT (methyl thiazolyl tetrazolium) process; the results show that the diosmin-copper(II) complex can inhibit B16 (mouse melanoma cells) and Hela (cervical cancer cells) more effectively than diosmin; anti-lipid peroxidation experiments and experiments of removing hydroxyl radicals by a salicylic acid method show that the diosmin-copper(II) complex has better capacity to remove free radicals than diosmin.