61results about How to "Effective healing" patented technology

The invention provides an ultrasonic and micro-forging composite device for improving the microstructure and performance of additively manufactured metal and an additive manufacturing method. The ultrasonic and micro-forging composite device comprises an energy converter, a pneumatic slider, a pneumatic slider connection frame, an amplitude transformer, a tool head and a roller. The energy converter is arranged in an energy converter shell, the energy converter shell is provided with an inserting piece and a pipeline connector, the amplitude transformer is connected to the lower end of the energy converter, the tool head is connected below the energy converter, the roller is located between the tool head and a workpiece, and the pneumatic slider is connected with the energy converter shell and the amplitude transformer through the pneumatic slider connection frame. By means of the ultrasonic and micro-forging composite device, the advantages that ultrasonic impact frequency is high and deformation generated by mechanical rolling is large are combined, the composite effect of ultrasonic impact and continuous rolling micro-forging can be achieved, and the purpose of improving the microstructure of the additively manufactured metal and the mechanical performance of parts is achieved. Through organic combination of the ultrasonic and micro-forging composite device and the additive manufacturing method with an existing additive manufacturing technology, the technical bottleneck that structure control is easy while performance control is difficult in existing metal additive manufacturing is solved, and innovation and development of metal rapid forming and manufacturing technologies are induced.

The invention relates to a regenerative implant of a cruciate ligament and a preparation method and application thereof. A surgical suture-shaped structure made of a degradable high molecule polymerization material is used as an initial mechanical support structure; a membrane-shaped structure made of a composite electrostatic spinning timbering material is used as a core structure for tissue remodeling and regeneration to be tightly wrapped in a winding mode on the initial mechanical support structure so as to form ligament regeneration elements; the multiple ligament regeneration elements form a ligament regeneration element set which is the regenerative implant of the ligament. The results of a goat animal experiment confirms that the implant is completely degraded within 52 weeks after being implanted to an organism, is induced to form an autogenous ligament tissue in the cavity of a knee joint, and induces the bone tunnel interface of a tibia and a femur to form tendon-bone healing; the maximum pulling force of the regenerated ligament is 20-60% that of a normal ligament tissue within 12 months after the implant is implanted to the organism.

Compressive composite seals for solid oxide fuel cell applications are provided. A compressive composite seal structure includes a glass phase to provide a gas tight seal, a reinforcing secondary phase to provide mechanical stability, and a compressive core. The compressive core is filled with an inert gas or air, providing a degree of compressibility, or alternatively is filled with a selected material to provide a more specific degree of compressibility and strength, such as a lower melting point glass. The compressive composite seal structure maintains an effective seal during the operating conditions of the SOFC. The self healing glass phase with the reinforcing secondary phase providing mechanical stability provides an elastic response at high temperature, effectively reduces crack propagation and if the temperature or pressure goes too high, the seal remains reliable and effective.

The invention provides a probiotic combined with atomized rhizoma bletillae polysaccharide-chitosan composite hydrogel and a preparation method and a purpose thereof, and belongs to the field of biomedical materials. The composite hydrogel is obtained in a way that after probiotics, atomized rhizoma bletillae polysaccharide solution and chitosan solution are mixed, an obtained mixture is subjectedto cross-linking reaction, and the atomized rhizoma bletillae polysaccharide is obtained in a way that rhizoma bletillae polysaccharide is oxidized by an oxidizing agent. The composite hydrogel has good mechanical properties and biocompatibility and does not have toxic or side effects for the liver and kidney, the three-dimensional porous net structure of the composite hydrogel is favorable for absorbing the redundant seepage of a wound to prevent the wound from being infected, and a good moist environment is provided for a wound surface healing process; meanwhile, the pH value of the hydrogel is faintly acid so as to be more favorable for protection and healing of the wound; and in addition, the composite hydrogel has excellent antibacterial performance and has an extremely good wound surface repairing effect. The atomized rhizoma bletillae polysaccharide-chitosan composite hydrogel combined with lactobacillus plantarum has a good application prospect on an aspect of clinical wound surface repairing, and is expected to be developed into a potential wound surface dressing.

The invention relates to a high-temperature anti-ablative coating formed on a base material as well as a preparation method and application of the high-temperature anti-ablative coating. The high-temperature anti-ablative coating comprises a SiC transition layer and a ZrC-SiC-Gd2o3 complex phase oxygen barrier layer formed by mixing ZrC, SiC and Gd2o3, which are sequentially formed on the base material, wherein the molar percentage of Gd2o3 in the ZrC-SiC-Gd2o3 complex phase oxygen barrier layer is 10-20%. The method comprises the steps as follows: preparing the SiC transition layer by using achemical vapor deposition method; and preparing the ZrC-SiC-Gd2o3 complex phase oxygen barrier layer by using a vacuum plasma spraying method. The high-temperature anti-ablative coating disclosed bythe invention has a high temperature self-healing property, so that an oxidizing atmosphere can be prevented from migrating to the interior of a material, the anti-ablative service time of the coatingat a high temperature is prolonged and an effective protection role is played on a ceramic matrix composite; and the high-temperature anti-ablative coating has the advantages of small porosity, highbonding strength, excellent high-temperature anti-ablative performance and the like.

The invention discloses a genetically recombinant stem cell preparation used for wound repair and scar inhibition and a preparation method thereof. The genetically recombinant stem cell preparation comprises a cell injection and a spraying agent which are separately stored. The preparation method comprises the following steps: subjecting a cell line stably expressing HGF to multiplication culture and separating out a cell component and a cultural supernatant; preparing the cell injection from the cell component; and preparing the spraying agent from the cultural supernatant. The invention also provides application of intrauterine blood stem cells stably expressing HGF to preparation of drugs used for repairing skin injuries and/or inhibiting scar formation. The genetically recombinant stem cell preparation can realize safe and efficient repair of wounds and inhibit scar formation.

The invention relates to a female care solution containing silver ions and a preparation method of the female care solution. The female care solution comprises the following components in percentage by weight: 0.001%-1% of a trivalent silver ion component, 0.05%-1% of an acidity regulator, 10%-20% of a humectant, 2%-6% of a freshener, 3%-8% of a skin care agent, 0.01%-1% of a pH modifier and the balance of deionized water. The invention further provides a preparation method of the female care solution. The method comprises the following steps: mixing the trivalent silver ion component with the deionized water; adding a proper amount of acidity regulator to adjust the pH value, and preparing a silver ion acid water aqueous solution; sequentially dissolving the humectant, the freshener and the skin care agent into the deionized water under the condition of continuously stirring and heating to 50 DEG C, so as to prepare a stable water solution; and finally mixing two solutions, and adjusting the pH value to be 4.5-5.0 with the pH modifier. The female care solution is capable of effectively removing a smell, relieving itching and protecting the skin in daily use, and has a certain prevention effect on gynaecopathia; and trivalent silver ions are capable of promoting wound repairing, promoting repair and regeneration of damaged cells, removing the necrotic tissue, promoting granulation, resisting bacteria, diminishing inflammation and improving micro-circulation of tissues.

The invention relates to a multi-layer interface coating, and a preparation method and application thereof. The multi-layer interface coating comprises SiBN coating layers and Si3N4 coating layers which are alternately formed on the surface of a substrate in sequence, wherein the number of layers of the SiBN coating layers is larger than or equal to 1, and is preferably in a range of 2-5.

The invention relates to the technical field of light-cured acrylate materials, and particularly relates to an acrylate material capable of being quickly cured by visible light and a preparation method thereof. The acrylate material comprises an acrylate monomer, an adhesive Bis-GMA, a bifunctional diluent monomer TEGDMA, CQ and DMAEMA, wherein acrylate material comprises x parts of the acrylate monomer, 7-x parts of the adhesive Bis-GMA, 3 parts of the bifunctional diluent monomer TEGDMA, the CQ and the DMAEMA; the x is greater than or equal to 0 and less than or equal to 7; the mass of eachof the CQ and the DMAEMA is 1% of the total mass of the acrylate monomer and the bifunctional diluent monomer TEGDMA. Fluorine-containing acrylate with low viscosity and high double-bond conversion rate is synthesized, is used as novel matrix resin of a photocuring repair material, and can be used as an encapsulation insulation micro-crack healing material of a dry-type air-core shunt reactor to realize effective repair of encapsulation insulation micro-cracks, so that an encapsulation insulation fault of a dry-type air-core shunt reactor is solved.

A method of preparing a malleable and/or self-healing polymeric or composite material is provided. The method includes providing a polymeric or composite material comprising at least one alkene-containing polymer, combining the polymer with at least one homogeneous or heterogeneous transition metal olefin metathesis catalyst to form a polymeric or composite material, and performing an olefin metathesis reaction on the polymer so as to form reversible carbon-carbon double bonds in the polymer. Also provided is a method of healing a fractured surface of a polymeric material. The method includes bringing a fractured surface of a first polymeric material into contact with a second polymeric material, and performing an olefin metathesis reaction in the presence of a transition metal olefin metathesis catalyst such that the first polymeric material forms reversible carbon-carbon double bonds with the second polymeric material. Compositions comprising malleable and/or self-healing polymeric or composite material are also provided.

The invention relates to a high-temperature self-healing multiphase coating formed on a base material and a preparation method and an application thereof. The high-temperature self-healing multiphasecoating consists of a SiC transition layer formed on the base material and a ZrB2-LaB6-TaSi2 multiphase surface layer formed by mixing ZrB2, LaB6 and TaSi2 in turn, wherein the ZrB2-LaB6-TaSi2 multiphase surface layer is composed of 60-80% of ZrB2, 10-20% of LaB6 and 10-20% of TaSi2 in mole percent. The method comprises the following steps: preparing a SiC transition layer by a chemical vapor deposition method; preparing the ZrB2-LaB6-TaSi2 multiphase surface layer by the vacuum plasma spraying method. The high-temperature self-healing multiphase coating of the invention has the high-temperature synergistic self-healing performance, can prevent the oxidation atmosphere from migrating into the material, prolong the ablation resistance time of the coating at the high temperature, and plays an effective protective role for the thermal structure material.

The invention discloses a bone repair and fixation assembly capable of realizing pre-tightening and retreating. The assembly comprises a bone connection plate and bone plate screws, wherein the bone connection plate and the bone plate screws are made of an absorbable material, a supporting surface of a screw head of each bone plate screw is provided with retreating-stopping strips, a plurality ofthrough-holes are arranged on the bone connection plate, a plurality of retreating-stopping teeth which are raised along the tightening direction of the corresponding bone plate screw are arranged around one end of each through-hole, and the retreating-stopping strips and the retreating-stopping teeth are cooperated to restrict the reverse rotation of the bone plate screws. The assembly can effectively fix a fracture site of a patient, and is not easily loosened.

Aiming at the shortcoming that crackles easily appear in gelatin casting wet biscuit, the invention provides an improved curing and drying proposal which can effectively heal the micro crackles appeared owing to demoulding, moving and too fast volatilization of surface solvent of the wet biscuit and ensures that complete and flawless biscuit is obtained after drying. The crackle healing proposal provided by the invention mainly comprises two steps which are curing and drying. In the curing stage, the gelation process of the monomers in the slurry is controlled by regulating a controlling curing temperature and curing time so as to ensure that part of cured monomers form gelatin in a bond crossing way and the other part of monomer are still preserved in the form of the monomers. In the subsequent drying process, the constant temperature and humidity drying proposal is adopted for causing the remained monomers in the biscuit to continously be cured and form bridging among sides of crackles, thus promoting the healing of the crackles. The crackle healing proposal provided by the invention has simple and reliable technique and is suitable for the preparation of blocks or porous ceramics.

The invention discloses a Chinese herbal medicine for treating an open wound and a preparation method thereof. The Chinese herbal medicine is prepared from the following 14 raw herbal materials: Artemisia anomala, Bletilla striata, asiatic toddalia root, leaf of chinese ilex, humifuse euphorbia herb, herba orostachyos, Ampelopsis delavayana (Franch.)Planch.[Vitis delavayana Franch.], polygonum bistorta, purslane, rheum officinale, bone-joining elixir, honeysuckle, folium isatidis and borneol. The 14 raw herbal materials are reasonably and scientifically combined and prepared into the Chinese herbal medicine. Through actual use, the Chinese herbal medicine has effects of stopping bleeding and diminishing inflammation, removing pus and drawing out toxin, clearing away heat and toxic materials, relieving swelling and pain, and removing slough and promoting growth of tissue regeneration. When mainly serving as an external medicine, the Chinese herbal medicine can be mainly used for treating open type wounds such as trauma (open wound), wound bleeding, bruise, puncture wound, cut wound, chop wound, avulsion, contusion and firearm injury; and moreover, the Chinese herbal medicine can also be used for treating wound diseases such as severe and lingering ulcerating wounds, small skin and soft tissue wounds of diabetes patients and erosive beriberi.

The invention provides a ceramic-based composite material for a brake disc of a high-speed train and a preparation method of the ceramic-based composite material. The ceramic-based composite material is prepared from the following components in percentage by volume: 32 to 62% of C fibers, 12 to 22% of a C substrate, 4 to 12% of an HfC substrate, and 10 to 34% of a ZrB2 substrate. According to the ceramic-based composite material, the advantages of the C/ C composite material, HfC and ZrB2 are combined, so that the thermal stress caused by thermal shock can be effectively relieved, and as a result, the thermal shock resistance can be obviously improved; the ceramic-based composite material has a good application prospect in the brake disc of the high-speed train.

A C / C-TaC-ZrB2 ceramic matrix composite comprises C fiber, a C matrix, a TaC matrix and a ZrB2 matrix. The TaC matrix is between the C / C matrix and ZrB2 matrix, the volume fraction of C fiber is 32-61%, the volume fraction of C matrix is 12-22%, the volume fraction of TaC matrix is 5-12%, and the volume fraction of ZrB2 matrix is 10-34%. The surface of the modified C / C composite is covered by TaC and ZrB2; the TaC matrix provides protection for the C fiber to prevent damage of Zr metal matrix to the matrix in the subsequent reaction; and at high temperature, B2O3 generated by oxidation of ZrB2 can effectively heal defects on the matrix, so as to further effectively prevent C / C matrix from oxidation.

A pharmaceutical composition for treatment and prevention of severely dehydrated soft tissue is disclosed. The pharmaceutical composition has ingredients that prevent the onset of dehydration and ingredients that increase the healing rate of dehydrated tissue that has become cracked. In particular, the present invention treats and prevents the dry-nose condition caused in oxygen respiratory therapy.

The invention relates to an application of a composition in the treatment of skin inflammations. The composition comprises mussel soft tissue extract and trypsin. The protein composition containing the trypsin and the mussel soft tissue extract combines two active components, has the efficacy of preventing histamine, preventing allergy, inhibiting microorganisms, healing scars and preventing oxidation, effectively relieves itches and pains, effectively prevents allergy, promotes ulcer healing, effectively restores skin damage conditions, and has the advantages of fast and rapid skin inflammation treatment effect, short treatment course, high cure rate, no toxic or side effects and no dependence.

The invention discloses an application of tissue-engineering bone in preparation of medicines, wherein the medicine is used for treating bone injury diseases. The tissue-engineering bone includes mesenchymal stem cells and pre-induction cells. The tissue-engineering bone has a strong capability of being differentiated into bone cells, is high in yield of the bone cells, and can provides required cells for tissue repair in injured parts of bone and quickly repair and cure the injured parts of bone. The tissue-engineering bone is convenient to prepare and is safe and reliable.