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Application of composition in treatment of skin inflammations

A technology of skin inflammation and composition, which is applied in the direction of skin diseases, drug combination, medical preparations containing active ingredients, etc., can solve the problem of high cost, achieve the effect of short treatment period, no dependence, and promote ulcer healing

Inactive Publication Date: 2017-04-26
BENGT I SAMUELSSON INST OF LIFE SCI CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The inventor disclosed the therapeutic effect of mussel mucin on skin inflammation in the invention patent applications PCT / CN2015 / 084492, PCT / CN2015 / 084493 and PCT / CN2015 / 084494, however, mussel mucin was obtained by chromatographic purification process A single protein, the cost is relatively higher

Method used

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  • Application of composition in treatment of skin inflammations
  • Application of composition in treatment of skin inflammations

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Example 1: The preparation method of mussel soft tissue extract.

[0042] Take mussels and remove their shells, collect 300 g of soft tissue, divide them into three parts, add 100 ml of the acidic solution in Table 1 below with a content of 0.3%, homogenate for 10 minutes, and centrifuge to obtain the supernatant, which is the mussel soft tissue extract.

[0043] The protein content and pH value in the supernatant were determined, and the protein content was determined by the Coomassie brilliant blue method.

[0044] Table 1

[0045] example acid solution protein content pH value 1 citric acid 2.6mg / ml 4.5 2 Acetic acid 3.5mg / ml 3.2 3 perchloric acid 3.0mg / ml 1.0

Embodiment 2

[0046] Example 2: Ointment for treating skin inflammation made from mussel soft tissue extract.

[0047] Take mussel soft tissue extract dry powder 100mg that Example 2 in Example 1 makes, add deionized water to dissolve and filter, add appropriate amount of vaseline to make ointment.

Embodiment 3

[0048] Example 3: An ointment for treating folliculitis with a composition of trypsin and mussel soft tissue extract.

[0049] Trypsin was purchased from Shaanxi Yuantai Biotechnology Company. The composition of the treatment folliculitis of mussel soft tissue extract, trypsin combination is made of following components: the mussel soft tissue extract dry powder 150mg that example 2 in embodiment 1 makes, trypsin dry powder 30mg, add deionized water fully Dissolve, filter and concentrate, add vaseline to make a paste product.

[0050] Collect 11 volunteers with folliculitis to participate in the test, apply 3 times a day, 7 days as a course of treatment, return visit after 4 courses of treatment and record the recurrence.

[0051] Efficacy Judgment Criteria:

[0052] Cure: cysts, itching, ulcers, nodules, pustules, skin itching, armpit pain, turbinate swelling, boils and other symptoms disappear;

[0053] Effective: the above symptoms are relieved;

[0054] Ineffective: no...

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PUM

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Abstract

The invention relates to an application of a composition in the treatment of skin inflammations. The composition comprises mussel soft tissue extract and trypsin. The protein composition containing the trypsin and the mussel soft tissue extract combines two active components, has the efficacy of preventing histamine, preventing allergy, inhibiting microorganisms, healing scars and preventing oxidation, effectively relieves itches and pains, effectively prevents allergy, promotes ulcer healing, effectively restores skin damage conditions, and has the advantages of fast and rapid skin inflammation treatment effect, short treatment course, high cure rate, no toxic or side effects and no dependence.

Description

technical field [0001] The invention relates to the field of biomedicine, and more specifically relates to the application of a composition in products for treating skin inflammation. Background technique [0002] Skin inflammation is a general term for various human skin diseases. It represents the allergic reaction of the skin to various substances such as chemicals, proteins, bacteria, and fungi. It may be caused by various internal and external infections or non-infectious factors. Usually There are exogenous dermatitis, endogenous dermatitis and other classified dermatitis, etc. The symptoms are mostly primary or secondary skin lesions such as itching, macules, papules, blisters, plaques, erosions, scabs or lichenification one or more of. Skin inflammation is very common and can be seen in all age groups. At present, the treatment for skin inflammation mainly includes: infectious inflammation actively controls infection, and non-infectious inflammation generally adopt...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/48A61P17/04A61P17/00A61P37/08A61P17/08A61P25/00A61K35/618
CPCA61K35/618A61K38/4826C12Y304/21004
Inventor 高敏
Owner BENGT I SAMUELSSON INST OF LIFE SCI CO LTD
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