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Salvianolic acid B containing medicine effective for wound healing and preparation method thereof

A technology of wound healing and salvianic acid, applied in the field of drugs containing salvianic acid B to treat wounds, can solve the problems of long treatment time and ineffective treatment effect

Active Publication Date: 2014-06-11
JIANGSU DANSHENG BIOLOGICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In daily life, people often encounter various wounds, causing certain wounds, but the existing medicines for treating bruises, knife and gun wounds have disadvantages such as long treatment time and inconspicuous therapeutic effect.

Method used

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  • Salvianolic acid B containing medicine effective for wound healing and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Embodiment 1: The salvianic acid B-containing drug effective for wound healing is composed of the following components in parts by weight: 45 parts of said salvianolic acid B, 30 parts of streptomycin sulfate powder, 3 parts of calcium pantothenate powder, tobacco 11 parts of amide powder, 300 parts of 150 mesh calcium oxide powder.

[0015] The method for preparing the above-mentioned salvianic acid B-containing drug effective for wound healing comprises the following steps:

[0016] (1) Pass the calcium oxide through a 150-mesh sieve, proportion by weight, and further grind it into fine powder;

[0017] (2) Add streptomycin sulfate powder, calcium pantothenate powder and nicotinamide powder to the above calcium oxide fine powder in sequence, grind and mix evenly to obtain a mixture;

[0018] (3) Add salvianolic acid B to the mixture in the above step (2), and grind it evenly;

[0019] (4) Spray the volatile oil to make a paste to obtain the medicine containing s...

Embodiment 2

[0021] Example 2: On the basis of Example 1, add 100 parts of Panax notoginseng, the production steps are the same as in Example 1, wash and dry the Panax notoginseng, pulverize, extract and concentrate with ethanol, add to step (2), mix.

[0022] Its usage is the same as in the embodiment, but the effect is better, the affected part remains intact, and there is no discomfort during use.

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Abstract

A disclosed salvianolic acid B containing medicine effective for wound healing is characterized by being composed of the following components in parts by weight, 30-80 parts of salvianolic acid B, 30-50 parts of streptomycin sulfate powder, 2-3 parts of calcium pantothenate powder, 11-15 parts of nicotinamide powder, and 100-300 parts of 150-mesh calcium oxide powder. The beneficial effect generated by employing the salvianolic acid B containing medicine provided by the invention comprise short treatment time and good treatment effect, and the salvianolic acid B containing medicine can be used to treat traumatic injury and sword and spear wounds without leaving scars. The invention also relates to a method for preparing the salvianolic acid B containing medicine effective for wound healing. The method comprises: sieving calcium oxide with a 150-mesh sieve, proportioning according to a weight ratio, and further grinding into a fine powder; successively adding streptomycin sulfate powder, calcium pantothenate powder and nicotinamide powder, and grinding; mixing uniformly to obtain a mixture; adding salvianolic acid B and grinding uniformly; and adding volatile oil by spraying, and preparing into a paste which is the salvianolic acid B containing medicine effective for wound healing.

Description

technical field [0001] The invention relates to the technical field of wound healing medicines for treating bruises and knife wounds, in particular to a medicine containing salvianic acid B for treating wounds. Background technique [0002] Salvianic acid B is the main water-soluble component of Salvia miltiorrhiza in the Labiatae family. It has various pharmacological activities such as anti-myocardial ischemia and hypoxia, and improving blood rheology. Synthesized tetrameric caffeic acid compounds (such as figure 1 shown). The chemical properties of salvianolic acid B are very unstable. In experiments, it was found that salvianic acid B in aqueous solution lost nearly 30% at low concentration (<0.1 mg / mL) overnight at room temperature, and its decomposition products were salvia miltiorrhiza, protocatechualdehyde, etc. [0003] Salvianic acid B is formed by condensation of three molecules of danshensu and one molecule of caffeic acid, such as figure 1 As shown...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/7036A61K31/343A61K31/197A61K31/455A61K36/258A61K47/02A61P17/02
Inventor 邵文远姜雪成
Owner JIANGSU DANSHENG BIOLOGICAL TECH
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