The invention discloses a method for preparing a mesoporous hydroxyapatite
nanometer particle with high specific surface area by virtue of a template method. The method comprises the following steps: firstly, mixing
calcium pantothenate, F123 and a certain amount of sym-trimethylbenzene to prepare an
emulsion and then dropwise adding a
phosphate solution with a certain pH value into the
emulsion, heating in a water bath, carrying out
reflux reaction and filtering to obtain a precipitate and finally calcining the precipitate in a
muffle furnace to remove a template to obtain the hydroxyapatite
nanometer particle with a mesoporous structure. The mesoporous hydroxyapatite prepared by the method disclosed by the invention has the characteristics of high specific surface area, large
drug loading amount and uniform pore size distribution and is distributed in a spherical nanometer state (the size is less than 100nm). The mesoporous hydroxyapatite serving as a
drug carrier can well penetrate through blood vessels and
cell walls to reach diseased cells. The entire preparation process is simple and the mesoporous hydroxyapatite can be produced in a large scale.