63 results about "Physalis pubescens" patented technology

The invention discloses a compound with antitumor activity, which is a compound shown as a formula I, and can be applied to preparation of an antitumor medicament and preparation of a medicament for preventing tumors. The invention further discloses a preparation method of the compound with antitumor activity. The method comprises the following steps of: performing reflux extraction on physalis pubescens L. with an extraction solvent to obtain an extracting solution; concentrating the extracting solution, diluting with water, and extracting with an organic solvent to obtain a dichloromethane extracting solution, wherein the organic solvent at least comprises dichloromethane; and concentrating the dichloromethane extracting solution, passing through a chromatographic column, eluting with an eluting system, and recrystallizing to obtain the compound with antitumor activity. The preparation method is simple and reliable, high operability and high efficiency are achieved, industrial mass production can be performed, popularization and application are facilitated, and a good application prospect is achieved.

The invention discloses electronic cigarette juice comprising physalis pubescens extractive. The electronic cigarette juice comprises, by weight, 1-5 parts of tobacco essence, 30-50 parts of propylene glycol, 30-50 parts of glycerol, 5-15 parts of purified water, 1-2 parts of nicotine and 1-10 parts of physalis pubescens extractive. The physalis pubescens extractive is obtained in the manner that after physalis pubescens is crushed, accelerated solvent extraction is carried out through 95% ethyl alcohol, and a molecular distillation mode is carried out. The means of combination of the accelerated solvent extraction and the molecular distillation is adopted in the physalis pubescens extractive, the extraction rate is high, the heat-sensitive light molecule substances are removed, and the flavor stability of the smoke of an electronic cigarette prepared through the physalis pubescens extractive is facilitated. Meanwhile, the physalis pubescens extractive can effectively prevent and reduce the irritation of smoke of the electronic cigarette to the throat and the lungs of a smoker, and the comfort level of the smoker is improved.

The invention discloses a method for processing preserved physalis pubescens fruits. The method specifically comprises the following steps: taking fresh physalis pubescens fruits as raw materials; firstly, shelling and cleaning raw material fruits, then carrying out color-protecting and sugaring treatment on the physalis pubescens fruits; finally, preparing the preserved physalis pubescens fruits by the procedures of baking, cooling and the like. By implementation of the method, the physalis pubescens fruits are subjected to color-protecting by using sodium pyrosulfite solution, and segmentation methods are respectively adopted in the sugaring and baking procedures, so that the preserved physalis pubescens fruits can have the color, strong fragrance and taste of the raw fruits. Thus, compared with the similar preserved fruits, the preserved physalis pubescens fruits have obvious market advantages.

The invention provides a method for extracting and purifying total flavonoids of Physalis pubescens fruits through antioxidant activity tracking and ultrasonic assistance. A certain amount of dried Physalis pubescens fruit powder is mixed with an ethanol solution with the concentration of 60%-95% in a certain solid-to-liquid ratio, extracted for a period of time under ultrasonic assistance at certain power, and an extraction solution is subjected to vacuum concentration; a concentrated solution is subjected to freeze drying treatment, powder is formed, and rough flavonoids of the Physalis pubescens fruits are obtained. The rough flavonoids are purified with AB-8 macroporous adsorption resin, firstly eluted with water for impurity removal and then eluted with an ethanol solution with the concentration of 20%-100%, filtrate is collected, and refined flavonoids of Physalis pubescens are obtained after vacuum concentration and drying. With the adoption of the method, purification is performed 1-3 times, and the purity is increased from 92.7% to 40.02%-65.3%. The flavonoids, prepared with the method, of Physalis pubescens have reducing power and the capability of scavenging negative oxygen ions, hydroxyl radicals and DPPH (diphenyl-picryl hydrazyl) free radicals, and the reducing power and the capability of scavenging negative oxygen ions, hydroxyl radicals and DPPH free radicals are both higher than those of the rough flavonoids and higher than Vc after purification, and the flavonoids of Physalis pubescens can be used for research and development of medicines, healthcare products, food and cosmetics. Extraction and purification of flavonoids are rapid, efficient and convenient, the oxidation resistance of the total flavonoids is reserved to the greatest extent, a basis is provided for industrial production of the flavonoids of Physalis pubescens fruits, and the method has certain practical significance.

The invention discloses application of physalis pubescens lactone B in preparing anti-cancer drugs. The physalis pubescens lactone B is a compound having a structure as shown in formula I; the physalis pubescens lactone B is combined with cis-platinum in use to prepare anti-cancer drugs; the compound having the structure as shown in the formula I serves as a novel STAT3 inhibitor, and simultaneously acts as a chemotherapy synergist which, combined with the cis-platinum, can take a synergistic action to greatly improve an anti-cancer activity. Test results show that the physalis pubescens lactone B, as a novel STAT3 inhibitor, has an anti-cancer activity and can be used for preparing anti-cancer drugs. When combining the physalis pubescens lactone B and the cis-platinum in use, a strong synergistic action is generated; compared to single use of the cis-platinum, the combination of the physalis pubescens lactone B and the cis-platinum shows stronger anti-cancer activity; the anti-cancer drugs prepared by the combination of the physalis pubescens lactone B and the cis-platinum are favorable for market promotion and have wide application prospect. The formula I is as shown in the specification.

The invention discloses a method for extracting uranidin from physalis pubescens fruit, and relates to a method for extracting uranidin, solving the problems that the conventional physalis pubescens uranidin extraction method is low in extraction rate and large in organic solvent consumption, a long time is needed, the uranidin is easy to oxidize and decompose in the extraction process, and industrial production cannot be achieved by means of supercritical extraction. The method disclosed by the invention comprises the following steps: firstly, juicing the physalis pubescens fruit; secondly, adding an organic solvent to perform ultrasonic-assisted extraction; thirdly, recycling and concentrating; fourthly, drying so as to obtain the uranidin. The method is high in extraction rate of the physalis pubescens uranidin in an ultrasonic extraction mode, the extraction rate is increased by 0.5-1.5% when being compared with an ordinary conventional ethanol leaching method, and moreover the extraction time is short, a small amount of the organic solvent is consumed, the condition is gentle, the extracted uranidin is not damaged, and theoretic basis is provided for industrial production of natural uranidin. The method is applied to extraction of uranidin in physalis pubescens fruit.

The present invention provides grape and physalis pubescens fruit compound fruit jam and a preparation method thereof. The compound fruit jam comprises the following components in parts by mass: 70-90 parts of grapes, 10-30 parts of physalis pubescens fruits, 0.1-0.3 part of citric acid, 30-40 parts of white granulated sugar and 0.4-0.6 part of pectin. The compound fruit jam is processed by raw material selecting, pretreating, softening, heating and concentrating, canning, sealing, sterilizing and cooling. The product is purplish red, moderate in sweetness and sourness, delicate in mouthfeel, even in texture state, not layered in jam body, not dehydrated, in gel slurry shapes, and coordinated in smell, overcomes the shortness that ordinary jams are single in flavor and relatively poor in mouthfeel, and is simple in technology, easy in device obtaining, simple and convenient in operations, and easy to an industrial production.

The invention provides a blueberry physalis pubescens compound beverage and a preparation method thereof and belongs to the technical field of food processing and biological fermentation. The blueberry physalis pubescens compound beverage is prepared from the following raw materials in parts by weight: 30-60 parts of blueberry, 50-80 parts of physalis pubescens, 20-30 parts of grape, 20-35 parts of white granulated sugar, 50-100 parts of drinking water and 3-8 parts of yeast. The preparation method comprises the following steps: squeezing physalis pubescens and blueberry into fruit juice; mixing the blueberry juice with the white granulated sugar and the grape and fermenting; mixing the blueberry juice with the yeast and fermenting; mixing the two products and distilling; adding the residual liquid into the drinking water and then filtering, and adding the salt for fertilizing and packaging, thereby acquiring the end product. The blueberry physalis pubescens compound beverage provided by the invention tastes sour and sweet, fuses fresh fruit fragrance and mellow blueberry flavor and is unique in flavor.

The invention relates to a qi-promoting and defecating oral liquid, which is prepared from an active ingredient, an additive and water, wherein the active ingredient is prepared from the following components in parts by weight: 10 to 30 parts of physalis pubescens and fructus cannabis liquid extract, 2 to 6 parts of fructus cannabis volatile oil, 1 to 4 parts of Guangxi radix curcumae extract and 1 to 4 parts of Ulmus macrocarpa Hance extract. The moisture content of the physalis pubescens and fructus cannabis liquid extract, Guangxi radix curcumae extract and the Ulmus macrocarpa Hance extract is less than 45%. The oral liquid provided by the invention has obvious qi-promoting and defecating effects, and has the advantages of quick absorption, quick effect and convenient taking.

The invention relates to molecule-specific marker primers for identifying Physalis pubescens and a method for quickly identifying Physalis pubescens by using the specific primers. The sequences of the primers are as follows: forward primer ST3MSJF: 5'-ATTGATAGGGTAAACCATG-3; and reverse primer ST3MSJR: 5'-CTGTAATAAAACAAAAGCG-3'. The specific primers ST3MSJF/ST3MSJR can be utilized to quickly identify the Physalis pubescens by a conventional PCR (polymerase chain reaction) process. The primers have the advantages of low consumption of laboratory samples, accurate results and high sensitivity; and the ST3MSJF/ST3MSJR are the specific amplification primers for Physalis pubescens, and if the sample is any other Physalis plant sample, the result is negative reaction. The method is simple and convenient; and by adopting the conventional PCR technique to perform detection, the consumed time is short, and the method can be completed within half a day.

The invention relates to a novel seedling culture and transplantation method of physalis pubescens. The fruit of the physalis pubescens is fragrant and sweet, contains various nutritional components needed by human bodies, has a certain medicinal value and is a fruit-medicine-dual-use economic plant promising in development prospect. The physalis pubescens is planted in many places of China and is mainly cultured by using an artificial seedling culture and transplantation manner, and the planting method of the physalis pubescens is complex in working procedure, low in efficiency and high in labor intensity. The novel seedling culture and transplantation method includes: manufacturing paper tubes 0.5-10cm in inner diameter, 0.001-0.5cm in thickness and 3-20cm in height, mutually adhering the paper tubes to obtain integrated combined seedling culture bowls, and performing expansion, smashing and sieving on crop straw to obtain straw powder which is suitable for seedling culture and used for filling the seedling culture bowls. The novel seedling culture and transplantation method has the advantages that the manual production of a traditional nutritional-bowl seedling culture and transplantation of the physalis pubescens is replaced by mechanical sowing and transplantation, labor intensity is reduced, and efficiency is increased.

The invention discloses a red kidney bean and sea crab meat bread roll. The red kidney bean and sea crab meat bread roll is composed of the following raw materials of, by weight, 230-270 parts of wheat flour, 8-13 parts of purslane freeze-dried powder, 5-6 parts of sweet potato stems, 7-11 parts of sea crab meat, 6-8 parts of red kidney beans, 9-10 pumpkin powder, 5-7 parts of black-bone chicken, 8-10 parts of physalis pubescens, 7-8 parts of kumquat, 2-3 parts of apple seeds, 1-2 parts of phacellanthus tubulosus, 3-4 parts of myosotis, 5-6 parts of roses, 4-5 parts of centella, 4-5 parts of canola oil, 2-4 parts of yeast, an appropriate amount of water and 7-10 parts of nutrient enrichment powder. The red kidney bean and sea crab meat bread roll is fragrant, sweet and delicious, the sea crab meat and the red kidney beans are added, the bread roll has the mouthfeel different from other bread, and the nutrients of the bread are further increased. In addition, traditional Chinese medicine material extracts like the apple seeds and the roses with a certain beauty and healthcare function are further added, so that beauty and healthcare can be effectively achieved, and the bread roll is beneficial to human health.

The invention discloses a Physalis pubescens and Chinese wolfberry can and belongs to a canned fruit food in daily life. The Physalis pubescens and Chinese wolfberry can is manufactured by matching Physalis pubescens (commonly called foreign girl) and Chinese wolfberry. The traditional canned fruit production process comprises the following steps of: cleaning, preboiling, rinsing, canning, adding syrup, sterilizing, vacuumizing, cooling and warehousing. The can is characterized in that: the Physalis pubescens is rich in vitamin C, and the Chinese wolfberry has sweet taste and neutral nature and has the effects of tonifying kidney, nourishing yin, nourishing liver, improving eyesight, tonifying qi and the like. The can is applicable to diseases such as emission with renal asthenia, soreness and weakness of waist and knees, dizziness, dim eyes and the like. The modern scientific research proves the statement, and believes that the Chinese wolfberry can reduce cholesterol, excite cranial nerves, strengthen the immunologic function, prevent and treat cancer and resist senility, has a beautifying effect and achieves the effect of extremely benefiting the human health. Fruits of the Physalis pubescens are golden yellow and the Chinese wolfberry is fresh red in appearance, and the yellow and red collocation is very elegant. The Physalis pubescens and Chinese wolfberry can has good using and popularization values.

The invention provides a method for quickly preparing gold nanoparticles through physalis pubescens pulp juice and relates to a preparation method of the gold nanoparticles. The method aims at solving the technological problems that by means of an existing chemical method for preparing the gold nanoparticles, due to the fact that more chemical reagents exist, pollution to the environment is caused easily, and the physical method cost is high. The method comprises the steps that physalis pubescens pulp is juiced, supernatant is taken after centrifuging, and the supernatant is the pulp juice; the pulp juice is diluted with deionized water, and a juice solution is obtained; and a chloroauric acid solution is stirred through a magnetic stirrer, the juice solution is added to the chloroauric acid solution, the color is changed from yellow to purple to wine red, stirring is continued, and the gold nanoparticle solution is obtained. The synthetic method is simple and fast, the cost is low, the pollution to the environment is small, and the method is used for preparing the gold nanoparticles.

The invention discloses Physalis pubescens baking-tolerant fruit cake and application thereof in pastry. The Physalis pubescens baking-tolerant fruit cake is made with, by weight, 90-110 parts of Physalis pubescens fruit, 0-50 parts of white granulated sugar, 0-50 parts of malt syrup, 0-5 parts of citric acid, 0-5 parts of tartaric acid, 0-5 parts of mannitol, and 0.3-30 parts of composite gel. Interms of the application of the Physalis pubescens baking-tolerant fruit cake in pastry, the Physalis pubescens baking-tolerant fruit cake may be consumed as fruit cake or baking-tolerant filling foruse in pastry described in State Standard of the People's Republic of China GB/T 20977-2007. The Physalis pubescens baking-tolerant fruit cake and the application thereof have the advantages that thePhysalis pubescens baking-tolerant fruit cake retains all nutrients and unique flavor and taste of Physalis pubescens fruit, has no pigment, is golden yellow, chewy and transparent, and is rarely damped by moisture; the Physalis pubescens baking-tolerant fruit cake may be baked with pastry foods, never runs as a fluid or dehydrates, and can retain the unique flavor and taste of Physalis pubescensfruit.

The invention discloses cooling tea with bitter gourd and a preparation method of the cooling tea. The cooling tea comprises the following materials in parts by weight: 80-90 parts of sliced bitter gourd, 20-30 parts of mint leaf, 20-30 parts of shredded pericarpium citri reticulatae, 20-30 parts of bracteantha bracteata, 20-30 parts of fructus gardeniae, 20-25 parts of granulated sugar, 7-9 parts of periwinkie meat, 10-12 parts of watermelon juice, 2-3 parts of fresh rosa chinensis, 3-4 parts of belgium endive, 2-3 parts of platycladi seed oil, 4-5 parts of physalis pubescens, 3-4 parts of water caltrop kernel, 4-5 parts of cheese, 5-7 parts of rolled mutton, 0.5-1 part of cortex cinnamomi, 0.5-1 part of codonopsis pilosula, 1-2 parts of radix puerariae, 1-2 parts of tuber fleeceflower stem, 1-2 parts of dandelion, proper amount of water and 40-50 parts of nutritional additive. The cooling tea disclosed by the invention is novel in process and unique in taste, is fragrant and pleasant, and has the effects of removing toxicity, decreasing internal heat, clearing heat, quenching thirst and reducing blood pressure; and the added traditional Chinese medicines have the effects of invigorating the spleen and the stomach and tonifying qi, replenishing and restoring lung qi, tonifying qi and engendering body fluid and tonifying qi and producing blood.

The invention provides physalis pubescens and onion wine and a preparation method thereof and belongs to the technical field of food processing and biological fermentation. The physalis pubescens and onion wine is prepared from the following raw materials in parts by weight: 80 to 120 parts of physalis pubescens, 50 to 80 parts of onion, 20 to 35 parts of carbon source material, 50 to 80 parts of drinking water, 3 to 5 parts of maltose oligosaccharide and 3 to 15 parts of saccharomycetes. The preparation method of the physalis pubescens and onion wine comprises the following steps: firstly, preparing the saccharomycetes; secondly, pressing the physalis pubescens and the onion into a physalis pubescens and onion mixed solution; thirdly, carrying out primary fermentation, after fermentation and aging; finally, sterilizing and canning to obtain a finished product. The physalis pubescens and onion wine disclosed by the invention has the efficacy of maintaining beauty and keeping young, delaying senescence and preventing cardiovascular and cerebrovascular diseases.

The invention discloses a production method of fructus physalis pubescens cans. The production method of the fructus physalis pubescens cans is characterized by taking 10-20 parts of fructus physalis pubescens, 20-40 parts of purified water and 5-10 parts of sugar candy as raw materials and comprising the following steps: cooking fructus physalis pubescens for 3 minutes at the temperature of 50 DEG C, cooling the fructus physalis pubescens at the temperature of 10 DEG C below zero, pre-boiling the fructus physalis pubescens for 5-10 minutes in a layered pot at the temperature of 100 DEG C to prepare hot soup; exhausting for 7-20 minutes in an exhausting box at the temperature of 82-96 DEG C; sterilizing for 5-25 minutes in a sterilizing box at the temperature of 100 DEG C, then cooling in stages at the temperatures of 65 DEG C, 45 DEG C and 30 DEG C till the temperature of the can is 37 DEG C. The production method of the fructus physalis pubescens cans is characterized by cooking fructus physalis pubescens at the temperature of 50 DEG C, cooling at the temperature of 10 DEG C below zero, exhausting for 7-20 minutes in exhausting box at the temperature of 82-96 DEG C and finally sterilizing for 5-25 minutes in the sterilizing box at the temperature of 100 DEG C; the temperature and the time of each of processes of cooking, cooling, preparing hot soup, exhausting, sealing, sterilizing and cooling are strictly controlled; after the special production method is applied to fructus physalis pubescens, the fructus physalis pubescens cans can reach the shelf life under the condition that no additive is added, so that the fructus physalis pubescens cans are relatively safe to eat.

The invention discloses a method for preparing a hard carbon material from biomass waste physalis pubescens leaves, and a sodium ion battery. The physalis pubescens leaves are wide in source and are often discarded in quantity, so that the physalis pubescens leaves are used as precursors, resources can be effectively saved, environmental pollution can be avoided, and the purpose of turning waste into wealth is achieved. The hard carbon material prepared from biomass waste physalis pubescens leaves shows relatively high first-week coulombic efficiency and good cycling stability, and is an excellent sodium ion battery negative electrode material. The biomass derived hard carbon material is used as the negative electrode of the sodium-ion battery, so that the cost of the battery can be greatly reduced, and the commercialization prospect of the sodium-ion battery is more favorably realized.

The invention discloses combined buccal tablets for alleviating asthenopia and a preparation method thereof, and belongs to the field of vision health food. The combined buccal tablets are mainly prepared by mixing 14-16 parts of a soybean saponin crude extract, 16-18 parts of corn flour, 19-21 parts of crude anthocyanin powder, 10-12 parts of black fungus powder and 10-12 parts of physalis pubescens extract juice powder evenly and tabletting. Soxhlet extraction, ultrasonic assisted ethanol extraction, enzymolysis extraction, spray drying and other processes are combined, and the prepared combined buccal tablets for alleviating asthenopia has the DPPH clearance rate reaching 79.32% and the hydroxyl radical (HO.) clearance rate of 65.27%%, the asthenopia symptoms after trial eating is obviously improved, the effective rate reaches 80%, and the average vision-improving endurance is improved; the results show that the combined buccal tablets prepared from Northeast special food comprisingsoybean, corn, blueberry, black fungus and physalis pubescens has strong free radical scavenging ability and good effect of alleviating asthenopia.