Application of benserazide hydrochloride in preparing medicine for treating acute inflammation
A technology for benserazide hydrochloride and acute inflammation, which is applied in the field of biomedicine and can solve the problems such as no benserazide hydrochloride treatment of acute inflammation yet.
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[0016] Establishment of acute inflammation animal model and drug treatment
[0017] All mice were housed in SPF-grade animal rooms, and fed and watered ad libitum. Fifty C57BL / 6 mice (purchased from the Institute of Model Biology, Nanjing University) were randomly divided into five groups, 10 in each group, respectively blank control group, model control group, benserazide hydrochloride low-dose group (25mg / kg / d), benserazide hydrochloride medium dose group (50mg / kg / d), benserazide hydrochloride high dose group (100mg / kg / d).
[0018] After adaptively feeding the above five groups of mice with basal feed for 1 week, the mice in the low-dose benserazide hydrochloride group were injected with benserazide hydrochloride 25 mg / kg / d, and the mice in the middle-dose benserazide hydrochloride group were injected with benserazide hydrochloride The mice in the 50mg / kg / d and high-dose benserazide hydrochloride groups were injected with 100mg / kg / d of benserazide hydrochloride, while the ...
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