Lysine hydrochloride and zinc gluconate tablets

A technology of zinc lysine and lysine hydrochloride, which is applied in the field of zinc lysine and its preparation, can solve problems such as malnutrition and growth retardation, reduce adverse drug reactions, solve growth retardation, and alleviate stomach problems. The effect of intestinal stimulation

Inactive Publication Date: 2017-05-31
SICHUAN DEFENG PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In view of the above deficiencies, the purpose of the present invention is to provide a compound lysine zinc glucose tablet, which can not only solve the growth retardation, malnutrition and anorexia caused by lack of lysine and zinc in children and adolescents It can also greatly reduce gastrointestinal irritation, reduce adverse drug reactions, and help reduce stomach discomfort, nausea, vomiting, constipation and other side effects

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] The preparation method of zinc lysine glucose tablet of the present invention:

[0020] (1) Weighing raw materials: 400g of lysine hydrochloride, 350g of zinc gluconate, 250g of zero more than seeds, 250g of hawthorn, 250g of astragalus;

[0021] (2) Take zero-yuzi, dry at 70°C, crush and pass through a 100-mesh sieve to obtain a fine powder of zero-yuzi;

[0022] (3) Take hawthorn and soak it in 10 times the weight of 75% ethanol solution for 60 minutes, ultrasonically extract it at 45°C with a power of 4000W for 30 minutes, and then filter it; then use 10 times the weight of 60% ethanol solution to ultrasonically extract the residue. The conditions are the same as above, filtered, and the filtrates are combined twice for later use, and the filtrate is concentrated to a relative density of 1.35g / ml to obtain the hawthorn extract;

[0023] (4) Take astragalus and add 10 times the amount of water to decoct 3 times, 1 hour each time, combine the decoction, concentrate th...

Embodiment 2

[0027] (1) Weigh raw materials:

[0028] Lysine Hydrochloride 250g, Zinc Gluconate 250g, Zero Yuzi 150g, Hawthorn 150g, Astragalus 150g;

[0029] (2) Take zero-yuzi, dry at 60°C, crush and pass through a 100-mesh sieve to obtain a fine powder of zero-yuzi;

[0030] (3) Take hawthorn and soak it in 10 times the weight of 75% ethanol solution for 60 minutes, ultrasonically extract it at 45°C with a power of 3000W for 40 minutes, and then filter it; the filter residue is then ultrasonically extracted with 10 times the weight of 60% ethanol solution, The conditions are the same as above, filtered, and the filtrates are combined twice for later use, and the filtrate is concentrated to a relative density of 1.30g / ml to obtain the hawthorn extract;

[0031] (4) Take astragalus and add 10 times the amount of water to decoct 3 times, each time for 1 hour, combine the decoction, concentrate the decoction to a relative density of 1.30g / ml, and obtain astragalus extract;

[0032] (5) Mi...

Embodiment 3

[0035] (1) Weigh raw materials: 400g of lysine hydrochloride, 350g of zinc gluconate, 350g of Zingyuzi, 350g of hawthorn, 350g of astragalus;

[0036] (2) Take zero-yuzi, dry at 90°C, crush and pass through a 100-mesh sieve to obtain a fine powder of zero-yuzi;

[0037] (3) Take hawthorn and immerse it in 10 times the weight of 90% ethanol solution for 90 minutes, ultrasonically extract it at 45°C with a power of 4000W for 40 minutes, and then filter it; the filter residue is then ultrasonically extracted with 10 times the weight of 75% ethanol solution, The conditions are the same as above, filtered, and the filtrates are combined twice for later use, and the filtrate is concentrated to a relative density of 1.40g / ml to obtain the hawthorn extract;

[0038] (4) Take astragalus and add 10 times the amount of water to decoct 3 times, 1 hour each time, combine the decoction, concentrate the decoction to a relative density of 1.40g / ml, and obtain astragalus extract;

[0039] (5)...

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PUM

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Abstract

The invention discloses lysine hydrochloride and zinc gluconate tablets. The lysine hydrochloride and zinc gluconate tablets are prepared from lysine hydrochloride, zinc gluconate, bulbil of common yam, hawthorn fruit and radix astragali. By adding effective constituents of bulbil of common yam, hawthorn fruit and radix astragali based on an existing formula of lysine hydrochloride and zinc gluconate tablets, the compound lysine hydrochloride and zinc gluconate tablets combining traditional Chinese medicine with western medicine are prepared. The prepared lysine hydrochloride and zinc gluconate tablets can well solve the problems of growth retardation, malnutrition and anorexia of children and teenagers due to lack of lysine and zinc, can also greatly relieve gastrointestinal tract irritation and reduce adverse drug reaction, and can reduce side effects such as stomach discomfort, nausea, vomiting and constipation.

Description

technical field [0001] The invention belongs to the technical field of medicine, and relates to a zinc lysine tablet and a preparation method thereof. Background technique [0002] Lysine is an indispensable and important element in children's growth and development; lack of appetite, slow growth, and mental retardation. Zinc gluconate is one of the important substances in the living body; during the growth of children, zinc deficiency often occurs; when lacking, anorexia, loss of appetite, listlessness, and developmental delay. Lysine Glucose Zinc Tablets can well solve the problems of growth retardation, malnutrition and lack of appetite in children and adolescents caused by lack of lysine and zinc. However, the existing Zinc Lysine Tablets have a certain stimulating effect on the gastrointestinal tract, and mild nausea, vomiting, constipation and other reactions can be seen in some children after taking it. There is no report in the published literature that "the compou...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8945A61K9/20A61K9/28A61P3/02A61P1/14A61K31/198A61K31/315
CPCA61K31/198A61K9/2054A61K9/2059A61K9/2806A61K33/30A61K36/481A61K36/734A61K36/8945A61K2236/15A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 张颖霆
Owner SICHUAN DEFENG PHARMA CO LTD
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