Composition, preparation method and application for improving or treating acute radiation-induced oropharyngeal mucositis

Abstract

The invention belongs to the field of traditional Chinese medicines, and relates to a composition for improving or treating acute radioactive oropharyngeal mucositis and a preparation method and application thereof. The composition for improving or treating the acute radioactive oropharyngeal mucositis has the effects of improving or treating discomfortable symptoms of acute stage reaction of the oropharyngeal mucositis such as dryness and pain of oropharynx, red and swelling, erosion, ulcer and the like caused by radiation chemotherapy. The composition for improving or treating the acute radioactive oropharyngeal mucositis is characterized by being prepared from the following crude drugs by weight proportion: 12-18 parts of rhizoma phragmitis, 8-12 parts of flos lonicerae, 12 to 18 parts of fructus momordicae, 7 to 12 parts of herba menthae, 1 to 3 parts of endothelium corneum gigeriae galli, and 3 to 8 parts of auricularia polytricha or white fungus. The composition for improving or treating the acute radioactive oropharyngeal mucositis has the effects of nourishing Yin and generating body fluid, diminishing inflammation, reducing phlegm, increasing appetite, greatly improving the discomfortable symptoms of the acute stage reaction of the oropharyngeal mucositis such as the dryness and pain of oropharynx, the red and swelling and the like, and being suitable for patients with head and neck cancer in the period of radiotherapy and chemotherapy to drink. In particular, the composition for improving or treating the acute radioactive oropharyngeal mucositis is prepared as a solid beverage of the traditional Chinese medicine, and has the advantages of being convenient to brew, good in taste and simple in production process.

Description

Technical field [0001] The present invention relates to a composition for improving or treating acute radiation oropharyngeal mucositis and its preparation method and application. It can improve or treat oropharyngeal dry pain, redness, erosion, ulcer and other acute phase of oropharyngeal mucositis caused by acute radiation chemotherapy. The effect of responding to uncomfortable symptoms belongs to the field of traditional Chinese medicine. Background technique [0002] With the gradual increase in the occurrence and detection rate of malignant tumors, the promotion of radiotherapy and the popularization of intracavitary irradiation, in order to improve the long-term survival rate of patients with malignant tumors, radiotherapy has gradually become an important method for the treatment of malignant tumors with chemotherapy. At the same time, after many head and neck malignant tumors receive radiotherapy, the incidence of the accompanying complication "radiation oropharyngeal muc...

AI Technical Summary

Problems solved by technology

[0003] In recent years, traditional Chinese medicine has been more and more accepted by everyone for its advantages of treating both symptoms and root causes and having less toxic and side effects. However, most of the current methods of taking traditional Chinese medicine are made into decoctions for decoction. This method requires long-term decoction, which is time-consuming and laborious. It is inconvenient to take, and the taste is not good; and the active ingredients in the traditional Chinese medicine cannot be completely extracted by decoction, resulting in the waste of traditional Chinese medicine