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Preparation method of peach blossom extracting solution and whitening composition containing peach blossom extracting solution

The technology of an extract and composition is applied in the field of preparation method of peach blossom extract and its whitening composition, which can solve the problems of cytotoxicity, inability to show whitening effect, use restriction, etc., achieve obvious whitening effect and reduce melanin production , low irritation effect

Active Publication Date: 2017-12-01
SHANGHAI FOREST CABIN BIOLOGICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The main whitening agents currently on the market are arbutin, ascorbic acid and its derivatives, kojic acid and its derivatives, licorice flavonoids, etc., but these do not show a perfect whitening effect. For example, arbutin contains the dangerous substance hydroquinone, Ascorbic acid is prone to oxidative inactivation, high concentrations of kojic acid and licorice flavonoids can cause cytotoxicity, and their use is limited

Method used

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  • Preparation method of peach blossom extracting solution and whitening composition containing peach blossom extracting solution
  • Preparation method of peach blossom extracting solution and whitening composition containing peach blossom extracting solution
  • Preparation method of peach blossom extracting solution and whitening composition containing peach blossom extracting solution

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Experimental program
Comparison scheme
Effect test

Embodiment 1～3

[0041] Embodiment 1~3 relates to the extraction and refining process of peach blossom extract

Embodiment 1

[0043] The preparation method is as follows:

[0044] Process steps:

[0045] 1. Extraction: Soak peach blossom petals for 2 hours; 10 times water (w / w) external circulation equipment at 65°C for 3 hours, remove residues, and obtain crude extract;

[0046] 2. Flocculation: add 0.3% chitosan flocculant (that is, the addition of flocculant is 0.3% of the weight of the crude extract) in the crude extract, stir at 100 rpm at room temperature, and filter;

[0047] 3. Microfiltration: Membrane with a molecular weight cut-off of 30nm, operating pressure 3-6bar, temperature ≤ 65°C, microfiltration until about 30% of the reflux liquid remains, add the same amount of water and continue microfiltration until the amount of exudate is equal to initial extract volume;

[0048] 4. Ultrafiltration: Membrane with a molecular weight cut-off of 1500D, the operating pressure is 10-15bar, and the temperature is kept ≤65°C;

[0049] 5. Preparation: Dilute the ultrafiltered filtrate with 1,3-buta...

Embodiment 2

[0051] The preparation method is as follows:

[0052] Process steps:

[0053] 1. Extraction: Soak peach blossom petals for 2 hours; extract 10 times water (w / w) external circulation equipment at 45°C for 3 hours, remove residues, and obtain crude extract;

[0054] 2. Flocculation: add 0.1% chitosan flocculant (that is, the addition of flocculant is 0.1% of the crude extract weight) to the crude extract, stir at 100 rpm at room temperature, and filter;

[0055] 3. Microfiltration: Membrane with a molecular weight cut-off of 30nm, operating pressure 1-3bar, temperature ≤ 45°C, microfiltration until about 30% of the reflux liquid remains, add the same amount of water and continue microfiltration until the amount of exudate is equal to initial extract volume;

[0056] 4. Ultrafiltration: Membrane with a molecular weight cut-off of 1500D, the operating pressure is 5-10bar, and the temperature is kept ≤45°C;

[0057] 5. Preparation: Dilute the ultrafiltered filtrate with 1,3-buta...

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Abstract

The invention provides a preparation method of a peach blossom extracting solution and a whitening composition containing the peach blossom extracting solution. The preparation method of the peach blossom extracting solution comprises the following steps: soaking peach blossoms, so as to obtain a crude extracting solution; adding a flocculating agent into the crude extracting solution for flocculation, then carrying out solid-liquid separation, collecting liquid parts for sequentially carrying out microfiltration and ultrafiltration, so as to obtain filtrate; and diluting the filtrate with 1,3-butanediol until the filtrate is equal to 0.05g / mL of a crude drug, so as to obtain the peach blossom extracting solution. The whitening composition contains the following components: the peach blossom extracting solution, a tea extracting liquid, a scutellaria baicalensis root extracting solution, an apple extracting solution, alpha-arbutin, glabridin, nicotinamide and VC ethylether. The whitening composition has the beneficial effects that the whitening effect is obvious, and the irritation is low; the cytotoxicity is reduced; the generation of risk substances in arbutin is reduced, and the oxygenolysis of VC ethylether is reduced.

Description

technical field [0001] The invention relates to a preparation method of a peach blossom extract and a whitening composition thereof, belonging to the technical field of cosmetics. Background technique [0002] Skin pigmentation is caused by ultraviolet rays, inflammatory stimuli, etc., which lead to the activation of the melanin production pathway of melanocytes, the expression of tyrosinase is enhanced, the activity is increased, and melanin is continuously produced and transported to the stratum corneum, resulting in excessive melanin in the epidermis calm. [0003] The main whitening agents currently on the market are arbutin, ascorbic acid and its derivatives, kojic acid and its derivatives, licorice flavonoids, etc., but these do not show a perfect whitening effect. For example, arbutin contains the dangerous substance hydroquinone, Ascorbic acid is easily oxidized and deactivated, and high concentrations of kojic acid and licorice flavonoids can cause cytotoxicity, so...

Claims

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Application Information

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IPC IPC(8): A61K8/9789A61Q19/02
CPCA61K8/97A61K2800/782A61Q19/02
Inventor 赵伟高宏旗陈贤
Owner SHANGHAI FOREST CABIN BIOLOGICAL TECH
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