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Oral care composition

An oral care and composition technology, which is applied in the fields of oral care compositions, granular pharmaceuticals, and tablets, can solve the problems such as the inability to dramatically increase the amount of saliva secretion, and achieve the purpose of preventing the occurrence and deterioration of caries and improving symptoms. Effect

Inactive Publication Date: 2018-01-02
日模株式会社
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0011] However, according to the above-mentioned prior art, although the secretion of saliva can be surely promoted and the symptoms of xerostomia can be improved, there is a problem that the amount of saliva secretion cannot be increased dramatically.

Method used

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0181] Hereinafter, the present invention will be specifically described with reference to test methods, examples, and comparative examples used in the present invention, but the present invention is not limited to these examples. In addition, when only % is described in the following example, it shows mass %.

[0182] In the present invention, as shown in Tables 1 and 2, the sample tablets obtained for the experimental study were contained in the mouths of five subjects A to E, and the amount of saliva secretion was measured.

[0183] [Table 1]

[0184]

[0185] [Table 2]

[0186]

[0187] Subject A is a man in his 50s, Subject B is a man in his 60s, Subject C is a man in his 40s, Subject D is a woman in his 50s, and Subject E is 50 How old are women. All of the test subjects A to E had symptoms of xerostomia. In particular, subject E was in a state of hardly salivating normally during treatment with an anticancer agent after tongue cancer surgery.

[0188] For eac...

Embodiment 2

[0218] Hereinafter, the present invention will be specifically described with reference to test methods, examples, and comparative examples used in the present invention, but the present invention is not limited to these examples. In addition, when only % is described in the following example, it shows mass %.

[0219] In the present invention, as shown in Tables 3 and 4, the sample tablets obtained for the experimental study were contained in the mouths of five subjects A to E, and the amount of saliva secretion was measured. [table 3]

[0220]

[0221] [Table 4]

[0222]

[0223] Subject A is a man in his 50s, Subject B is a man in his 60s, Subject C is a man in his 40s, Subject D is a woman in his 50s, and Subject E is 50 How old are women. All of the test subjects A to E had symptoms of xerostomia. In particular, subject E was in a state of hardly salivating normally during treatment with an anticancer agent after tongue cancer surgery.

[0224] For each of thes...

Embodiment 3

[0230] The sample tablet obtained for the experimental study of the toothache relieving agent was made to be contained in the mouth of the test subject, and the toothache relieving effect was heard through interviews.

[0231] A sample tablet was prepared by mixing the auxiliary components and main components shown in Table 5 below. The numerical values ​​in Table 5 are represented by mass % relative to the total mass.

[0232] [table 5]

[0233]

[0234] The test subject was a male in his 50s. According to the diagnosis by the dentist, caries in the mandibular first premolar reached the pulp, and the diagnosis was C3. In addition, as a result of interviewing the test subjects before the experiment, it was confirmed that they had subjective symptoms regarding toothache.

[0235] The test subject bit the sample tablet with the carious mandibular first premolar for 10 minutes, and the effect of relieving toothache was evaluated in five stages. The closer the relief effect ...

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Abstract

Provided is an oral care composition capable of completely preventing cavities by inducing the secretion of saliva in large quantities and thereby maintaining and improving the health of the oral cavity. Specifically provided is an oral care composition that is placed in the oral cavity to improve the health of the oral cavity, said oral care composition being characterized by comprising, in termsof mass% relative to the total mass of the composition, 1-30% phosphoryl organosaccharides of calcium, 0.01-10% lactoferrin, and 1-5% magnesium carbonate or 1-5% suicralose.

Description

technical field [0001] The present invention relates to an oral care composition, a tablet, and a granule drug, which are suitable for maintaining the health of the oral cavity by secreting more saliva in the oral cavity that exhibits bactericidal and antibacterial effects. Background technique [0002] Saliva has the functions of keeping the inside of the mouth moist, facilitating the digestion of food, and cleaning the inside of the mouth through physical or biochemical mechanisms. In addition, this saliva keeps the pH in the oral cavity constant by utilizing bicarbonate ions (HCO 3 - ) further maintains the pH in the oral cavity at a neutral level, thereby taking on the role of preventing dental caries (dental caries). That is, saliva plays an important role in food intake and maintenance of oral cavity health. [0003] However, in recent years, the number of people suffering from dry oral tissue due to a decrease in the amount of saliva secretion, that is, so-called d...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/702A61K33/10A61K38/16A61P1/02A61P43/00
CPCA61K45/06A61K33/06A23L2/66A23L33/10A23L33/19C12Y111/01007A61Q5/02A61K8/64A61Q5/12A61Q11/00A61K8/732A61Q19/00A61Q19/10A23L27/00A61P43/00A23L2/52A61K31/702A61K33/00A61K33/10A61K38/40A61K38/44A61K2300/00A23L33/30A23L33/16A23L21/10A23V2002/00A61K47/26
Inventor 川濑太郎川濑龙二川濑明美
Owner 日模株式会社
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