The invention discloses a mask for activating cell re-growth and awakening young state and a preparation method thereof. The mask comprises the following raw materials: polyvinyl alcohol, vegetable hydrolyzed collagen, propylene glycol, sorbitol, tamaric acid, reuben oil, hydrogenated lecithin, xanthan gum, aloe gum, carbomer, sodium trehalose, dipotassium glycyrrhizinate, hydrolyzed silk protein,arginine, platinum powder, beta; dextran, resveratrol, sodium hyaluronate, benzalkonium hyaluronate, inositol hexaphosphate, silver oxide, volcanic rock powder, diatomite, tetrasodium pyrophosphate,pure water, fatty acid polyoxyethylene ether, algal fiber, tea powder, ganoderma lucidum, 4-methyl hydroxybenzoate, vitamin E and antibacterial modifying agent, wherein the mask for activating the cell to grow again and awakening the young state is obtained through the steps of preparing material A, preparing material B, preparing mixture, sterilizing the mixture, and the like. The mask has excellent antibacterial effect.