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TCM (traditional Chinese medicine) composition for treating coronary heart diseases

A composition and coronary heart disease technology, which is applied in the direction of drug combination, cardiovascular system diseases, and pharmaceutical formulations, can solve the problems of increasing the number of people who accept it, low content of active ingredients, and large dosage, so as to reduce the incidence of coronary heart disease , Stable curative effect, small dose effect

Inactive Publication Date: 2018-02-16
孙志强
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] However, due to the low content of active ingredients in Chinese medicine decoction pieces, large dosage, inconvenient, and bitter taste, it is not easy to be accepted by patients. The content of ingredients is increased, the dosage is reduced, it is convenient to take, and the good medicine is no longer bitter, which increases the number of people who accept it

Method used

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  • TCM (traditional Chinese medicine) composition for treating coronary heart diseases

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Comparison scheme
Effect test

Embodiment 1

[0054] Prescription: Codonopsis total polysaccharides 100g, astragalus total saponins 80g, salvia phenolic acids 120g, toosendan total flavonoids 80g

[0055] Preparation method: Preparation of total polysaccharides of Codonopsis pilosula: Take Codonopsis pilosula, add water 10 times the weight of the herbs, extract 3 times, 2 hours each time, filter, combine the filtrates, concentrate under reduced pressure to 1g crude drug / mL, add ethanol until the alcohol content is 50 %, keep it refrigerated for 12 hours, filter, continue to add ethanol to the filtrate until the alcohol content is 80%, collect the precipitate, repeatedly purify the precipitate, add 15 times the amount of water to fully dissolve, add 4% tannic acid, mix well, and let it stand for 12 hours. Centrifuge, take the supernatant and add 2% activated carbon, heat and decolorize at 80°C for 3 times, 0.5h each time, filter, concentrate the filtrate under reduced pressure, and dry to obtain the total polysaccharides of...

Embodiment 2

[0061] Prescription: Codonopsis total polysaccharides 100g, astragalus total saponins 80g, salvia phenolic acids 120g, toosendan total flavonoids 80g;

[0062] Preparation method: Preparation of total polysaccharides of Codonopsis pilosula: Take Codonopsis pilosula, add water 10 times the weight of the herbs, extract 3 times, 2 hours each time, filter, combine the filtrates, concentrate under reduced pressure to 1g crude drug / mL, add ethanol until the alcohol content is 50 %, keep it refrigerated for 12 hours, filter, continue to add ethanol to the filtrate until the alcohol content is 80%, collect the precipitate, repeatedly purify the precipitate, add 15 times the amount of water to fully dissolve, add 4% tannic acid, mix well, and let it stand for 12 hours. Centrifuge, take the supernatant and add 2% activated carbon, heat and decolorize at 80°C for 3 times, 0.5h each time, filter, concentrate the filtrate under reduced pressure, and dry to obtain the total polysaccharides o...

Embodiment 3

[0068] Prescription: Codonopsis total polysaccharides 100g, astragalus total saponins 80g, salvia phenolic acids 120g, toosendan total flavonoids 80g;

[0069] Preparation method: Preparation of total polysaccharides of Codonopsis pilosula: Take Codonopsis pilosula, add water 10 times the weight of the herbs, extract 3 times, 2 hours each time, filter, combine the filtrates, concentrate under reduced pressure to 1g crude drug / mL, add ethanol until the alcohol content is 50 %, keep it refrigerated for 12 hours, filter, continue to add ethanol to the filtrate until the alcohol content is 80%, collect the precipitate, repeatedly purify the precipitate, add 15 times the amount of water to fully dissolve, add 4% tannic acid, mix well, and let it stand for 12 hours. Centrifuge, take the supernatant and add 2% activated carbon, heat and decolorize at 80°C for 3 times, 0.5h each time, filter, concentrate the filtrate under reduced pressure, and dry to obtain the total polysaccharides o...

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Abstract

The invention discloses TCM (traditional Chinese medicine) effective part composition for treating coronary heart diseases and belongs to the field of TCM. The composition is prepared from radix codonopsis total polysaccharides extracted from radix codonopsis, radix astragali total saponins extracted from radix astragali, total salvianolic acid extracted from radix salviae miltiorrhizae and fructus toosendan total flavone extracted from fructus toosendan in certain proportion, conventional pharmaceutic auxiliary materials are added, various types of dosage forms are prepared, and the composition can be applied to treatment of the coronary heart diseases clinically.

Description

technical field [0001] The invention relates to a composition of effective parts of traditional Chinese medicine with the effect of treating coronary heart disease and a preparation method thereof, in particular to a composition of effective parts of Chinese medicine extracted from Codonopsis radix, Radix Astragali, Salvia miltiorrhiza and Toosendan, and a preparation method thereof, belonging to traditional Chinese medicine field. Background technique [0002] Coronary heart disease is the abbreviation of coronary heart disease, which is the most common heart disease. It refers to myocardial dysfunction or organic disease caused by coronary artery stenosis and insufficient blood supply, so it is also called ischemic cardiomyopathy. The incidence of coronary heart disease is closely related to the degree and number of coronary artery atherosclerotic stenosis. Coronary heart disease is one of the diseases with the highest mortality rate in the world. According to the report o...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/58A61P9/10A61K31/715
CPCA61K31/715A61K36/481A61K36/537A61K36/58A61K2236/33A61K2236/331A61K2236/333A61K2236/35A61K2236/39A61K2236/51A61K2236/53A61K2236/55A61K2300/00
Inventor 孙志强
Owner 孙志强
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