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A Method for Adjusting Staining Components of Pathological Image

A technology of pathological image and adjustment method, which is applied in the field of adjustment of dyeing components of pathological images, and can solve problems such as inability to separate different dye components

Active Publication Date: 2021-08-06
BEIHANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] The purpose of the present invention is to provide a method for adjusting the dyeing components of pathological images, so as to solve the problem that the existing image processing technology cannot separate the components of different dyes in pathological images and realize the independent adjustment of different dyes in pathological images

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  • A Method for Adjusting Staining Components of Pathological Image
  • A Method for Adjusting Staining Components of Pathological Image
  • A Method for Adjusting Staining Components of Pathological Image

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Embodiment 1

[0061] A method for adjusting the dyeing components of pathological images, the specific process is as follows figure 2 shown, including the following steps:

[0062] 1. Collection of pathological slides

[0063] The pathological image is input into the computer through the pathological slice scanning device, and the image is represented in the RGB color space, where the values ​​of the R, G, and B channels whose pixel coordinates are (x, y) are expressed as:

[0064] I(x,y)=[I r (x,y),I g (x,y),I b (x,y)] (3)

[0065] where I r (x,y), I g (x,y), I b (x, y) respectively represent the values ​​of the three color channels of red, green and blue, and I c (x,y)∈[0,1], c=r,g,b.

[0066] 2. Saturation and brightness correction

[0067] When scanning pathological images, due to poor lighting conditions and other reasons, the saturation and brightness of the images will be poor. Therefore, it is necessary to correct the brightness saturation of the pathological image. The...

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Abstract

The invention discloses a method for adjusting the dyeing components of pathological images. First, the brightness and saturation of the pathological slices are corrected in the hue, saturation, and brightness (HSV) space of the collected pathological slices, and the saturation of the pathological slices is corrected. Intensity and brightness, separation of dyeing components, adjustment of dyeing components, synthesis of dyeing components, an algorithm for adjusting the content of a single dyeing component, achieved the effect of independent adjustment of different dyes in pathological images, and effectively completed the task of dyeing separation , to assist the pathologist's diagnosis.

Description

technical field [0001] The invention relates to the field of digital image processing, in particular to a method for adjusting dyeing components of pathological images. Background technique [0002] Digital pathological images are high-resolution digital images obtained by scanning pathological slices through automatic microscopes or optical magnification systems, and have been widely used in pathological clinical diagnosis. The color of the pathological section is obtained by dyeing, and the most commonly used staining method is hematoxylin and eosin (H-E) staining. However, human factors such as manual operation techniques and differences in the ratio of dyeing agents in the staining process will cause differences in the staining quality of pathological sections; at the same time, differences in the lighting environment during the scanning of slices will also make the brightness of the collected digital pathology images There is a large difference in saturation. These di...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G06T7/90G06T5/00
CPCG06T7/90G06T2207/10056G06T2207/30096G06T5/90
Inventor 姜志国郑钰山张浩鹏谢凤英麻义兵
Owner BEIHANG UNIV